A pharmacokinetic study on Z-(±)-2-(1-benzylindole-3-yl-methylene) azabicyclo[2.2.2]octane-3-ol; a novel radio-sensitization agent

Cancer Chemotherapy and Pharmacology

Volumn 60, Issue 6, 2007, Pages 915-919

  Al Ghananeem, Abeer M ^a   Albayati, Zaineb F ^a   Malkawi, Ahmad ^a   Sonar, Vijayakumar N ^a   Freeman, Michael L ^b   Crooks, Peter A ^a  

^a University of Kentucky   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Cancer; Pharmacokinetics; Radio sensitization; Radiotherapy; Therapeutic hyperthermia

Indexed keywords

2 (BENZYLINDOLE 3 YL METHYLENE) AZABICYCLO [2.2.2] OCTANE 3 OL; OCTANOL; RADIOSENSITIZING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BICYCLO COMPOUNDS, HETEROCYCLIC; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; RADIATION-SENSITIZING AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TISSUE DISTRIBUTION;

EID: 34548576855     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-007-0425-8     Document Type: Article

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