Quality control of routine, experimental and real-time aged diphtheria toxoids by in vitro analytical techniques

Vaccine

Volumn 25, Issue 39-40, 2007, Pages 6863-6871

  Metz, Bernard ^a,b   Jiskoot, Wim ^b,c   Mekkes, Dirk ^a   Kingma, Robert ^a   Hennink, Wim E ^b   Crommelin, Daan J A ^b   Kersten, Gideon F A ^a  

^a NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Biosensor analyses; Diphtheria toxoid; Physicochemical techniques; Potency; Quality control

Indexed keywords

DIPHTHERIA VACCINE;

ACCURACY; ACETYLATION; ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSENSOR; CIRCULAR DICHROISM; CONTROLLED STUDY; DENATURATION; DRUG DETERMINATION; DRUG POTENCY; DRUG QUALITY; DRUG SAFETY; FLUORESCENCE ANALYSIS; IMMUNOHISTOCHEMISTRY; METHYLATION; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SHELF LIFE; VALIDATION PROCESS; VERO CELL;

ANIMALS; BIOSENSING TECHNIQUES; CERCOPITHECUS AETHIOPS; CIRCULAR DICHROISM; DIPHTHERIA TOXOID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MICE; PROTEIN CONFORMATION; QUALITY CONTROL; TIME FACTORS; VERO CELLS;

EID: 34548574820     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.07.009     Document Type: Article

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