The probability of identifying a 10/10 HLA allele-matched unrelated donor is highly predictable

Bone Marrow Transplantation

Volumn 40, Issue 6, 2007, Pages 515-522

  Tiercy, J M ^a   Nicoloso, G ^b   Passweg, J ^a   Schanz, U ^c   Seger, R ^d   Chalandon, Y ^a   Heim, D ^e   Gungor T ^d   Schneider, P ^f   Schwabe, R ^b   Gratwohl, A ^e  

^a UNIVERSITY HOSPITAL   (Switzerland)

^b Swiss Blood Stem Cells   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^e UNIVERSITY HOSPITAL BASEL   (Switzerland)

^f Blood Transfusion Center   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CAUCASIAN; DONOR; GENE FREQUENCY; HAPLOTYPE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY GENE; HISTOCOMPATIBILITY TEST; HLA MATCHING; HLA TYPING; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROBABILITY; SURVIVAL RATE;

ALGORITHMS; ALLELES; HAPLOTYPES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HUMANS; KAPLAN-MEIERS ESTIMATE; PREDICTIVE VALUE OF TESTS; PROBABILITY; REGISTRIES; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS;

EID: 34548534393     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705787     Document Type: Article

References (24)

1. Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med 2006; 354: 1813-1826.
2. Gratwohl A, Baldomero H, Frauendorfer K, Urbano-Ispizua A, Niederwieser D. Results of the EBMT activity survey 2005 on hematopoietic stem cell transplantation: Focus on increasing use of unrelated donors. Bone Marrow Transplant 2007; 39: 71-87.
3. Heemskerk MB, van Walraven SM, Cornelissen JJ, Barge RM, Breduis RG, Egeler RM et al. How to improve the search for an unrelated haematopoietic stem cell donor. Faster is better than more!. Bone Marrow Transplant 2005; 35: 645-652.
4. Tiercy JM, Villard J, Roosnek E. Selection of unrelated bone marrow donors by scrology, molecular typing and cellular assays. Transplant Immunol 2002; 10: 215-221.
5. Hurley CK, Wagner JE, Setterholm MI, Confer DL. Advances in HLA: practical implications for selecting adult donors and cord blood units. Biol Blood Marrow Transplant 2006; 12 (1 Suppl 1): 28-33.
6. Tiercy J-M, Bujan-Lose M, Chapuis B, Gratwohl A, Gmur J, Seger R et al. Bone marrow transplantation with unrelated donors: What is the probability of identifying an HLA-A/B/Cw/DRB1/B3/B5/DQB1-matched donor? Bone Marrow Transplant 2000; 26: 437-441.
7. Petersdorf EW, Anasetti C, Martin PJ, Gooley T, Radich J, Malkki M et al. Limits of HLA mismatching in unrelated hematopoietic cell transplantation. Blood 2004; 104: 2976-2980.
8. Souillet G, Rey S, Bertrand Y, Pujol M, Pondarre C, Bourgeot JP et al. Outcome of unrelated bone marrow donor searches in 174 children resulting in 45 patients transplanted in the HLA-matched and -mismatched situation. Bone Marrow Transplant 2000; 26: 31-43.
9. Pedron B, Duval M, Elbou OM, Moskwa M, Jambu M, Vilmer E et al. Common genomic HLA haplotypes contributing to successful donor search in unrelated hematopoietic transplantation. Bone Marrow Transplant 2003; 31: 423-427.
10. Pedron B, Yakouben K, Adjaoud D, Auvrignon A, Landman J, Guerin V et al. Listing of common HLA alleles and haplotypes based on the study of 356 families residing in the Paris, France, area: Implications for unrelated hematopoietic stem cell donor selection. Hum Immunol 2005; 66: 721-731.
11. Tiercy J-M. Analysis of 250 HLA-B44 genotypes in European Caucasoids: high diversity and preferential ABCDRB1 associations in B*4402, B*4403, and B*4405 haplotypes. Tissue Antigens 2005; 65: 429-436.
12. Cao K, Hollenbach J, Shi X, Shi W, Chopek M, Fernandez-Vina MA. Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum Immunol 2001; 62: 1009-1030.
13. Klitz W, Maiers M, Spellman S, Baxter-Lowe LA, Schmeckpeper B, Williams TM et al. New HLA haplotype frequency reference standards: high-resolution and large sample typing of HLA DR-DQ haplotypes in a sample of European Americans. Tissue Antigens 2003; 62: 296-307.
14. Hurley CK, Baxter-Lowe LA, Begovich AB, Fernandez-Vina M, Noreen H, Schmeckpeper B et al. The extent of HLA class II allele level disparity in unrelated bone marrow transplantation: Analysis of 1259 National Marrow Donor Program donor-recipient pairs. Bone Marrow Transplant 2000; 25: 385-393.
15. Schipper RF, D'Amaro J, Bakker JT, Bakker J, van Rood JJ, Oudshoorn M. HLA gene haplotype frequencies in bone marrow donors worldwide, registries. Hum Immunol 1997; 52: 54-71.
16. Williams F, Meenagh A, Darke C, Acosta A, Daar AS, Gorodezky C et al. Analysis of the distribution of HLA-B alleles in populations from five continents. Hum Immunol 2001; 62: 645-650.
17. Grundschober C, Rufer N, Sanchez-Mazas A, Madrigal A, Jeannet M, Roosnek E et al. Molecular characterization of HLA-C incompatibilities in HLA-ABDR-matched unrelated bone marrow donor-recipient pairs. Sequence of two new Cw alleles (Cw*02023 and Cw*0707) and recognition by cytotoxic T lymphocytes. Tissue Antigens 1997; 49: 612-623.
18. Prasad VK, Heller G, Kernan NA, O'Reilly RJ, Yang SY. The probability of HLA-C matching between patient and unrelated donor at the molecular level: Estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles. Transplantation 1999; 68: 1044-1050.
19. Boucher K, Mori M, Milford E, Beatty PG. Estimation of HLA-A, -B, -DR haplotype frequencies in five racial groups represented in the NMDP donor file. In: Gjertson DW, Terasaki PL (eds). HLA 1998. Published by ASHI: Lenexa, KS, USA, pp 57-78.
20. Müller C-H, Ehninger G, Goldmann SF. Gene and haplotype frequencies for the loci HLA-A, HLA-B, and HLA-DR based on over 13 000 German blood donors. Hum Immunol 2003; 64: 137-151.
21. Hurley CK, Fernandez-Vina M, Hildebrand WH, Noreen HJ, Trachtenberg E, Williams TM et al. A high degree of HLA disparity arises from limited allelic diversity: Analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. Hum Immunol 2007; 68: 30-40.
22. Petersdorf EW. Risk assessment in haematopoietic stem cell transplantation: Histocompatibility. Best Pract Res Clin Haematol 2007; 20: 155-170.
23. Tay GK, Witt CS, Christiansen FT, Charron D, Baker D, Herrmann R et al. Matching for MHC haplotypes results in improved survival following unrelated bone marrow transplantation. Bone Marrow Transplant 1995; 15: 381-385.
24. Chalandon Y, Tiercy J-M, Schanz U, Gungor T, Seger R, Halter J et al. Impact of high resolution matching in allogeneic unrelated donor stem cell transplantation in Switzerland. Bone Marrow Transplant 2006; 37: 906-916.