메뉴 건너뛰기




Volumn 28, Issue 11, 2007, Pages 1637-1643

Genetic risk profiles for Alzheimer's disease: Integration of APOE genotype and variants that up-regulate inflammation

Author keywords

Alzheimer's disease; Cognitive deterioration; Gene polymorphism; GoM analysis; Inflammation

Indexed keywords

AGE DISTRIBUTION; AGED; ALLELE; ALZHEIMER DISEASE; APOE GENE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; FUZZY SYSTEM; GENE; GENE CONTROL; GENE FUNCTION; GENE LOCUS; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; INFLAMMATION; INNATE IMMUNITY; ITALY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; UPREGULATION;

EID: 34548532090     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2006.07.007     Document Type: Article
Times cited : (68)

References (39)
  • 1
    • 0034620538 scopus 로고    scopus 로고
    • A randomized controlled trial of prednisone in Alzheimer's disease, Alzheimer disease cooperative study
    • Aisen P.S., Davis K.L., Berg J.D., Schafer K., Campbell K., Thomas R.G., et al. A randomized controlled trial of prednisone in Alzheimer's disease, Alzheimer disease cooperative study. Neurology 54 3 (2000) 588-593
    • (2000) Neurology , vol.54 , Issue.3 , pp. 588-593
    • Aisen, P.S.1    Davis, K.L.2    Berg, J.D.3    Schafer, K.4    Campbell, K.5    Thomas, R.G.6
  • 2
    • 0037638809 scopus 로고    scopus 로고
    • Effects of refecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial
    • Aisen P.S., Shafer K.A., Grundman M., Pfeiffer E., Sano M., Davis K.L., et al. Effects of refecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial. JAMA 289 (2003) 2865-2867
    • (2003) JAMA , vol.289 , pp. 2865-2867
    • Aisen, P.S.1    Shafer, K.A.2    Grundman, M.3    Pfeiffer, E.4    Sano, M.5    Davis, K.L.6
  • 3
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261 (1993) 921-923
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3    Schmechel, D.E.4    Gaskell, P.C.5    Small, G.W.6
  • 4
    • 0033789445 scopus 로고    scopus 로고
    • Density profiles of Alzheimer disease regional brain pathology for the Huddinge Brain Bank: pattern recognition emulates and expands upon Braak staging
    • Corder E.H., Woodbury M.A., Volkmann I., Madsen D.K., Bogdanovic N., and Winblad B. Density profiles of Alzheimer disease regional brain pathology for the Huddinge Brain Bank: pattern recognition emulates and expands upon Braak staging. Exp Gerontol 35 (2000) 851-864
    • (2000) Exp Gerontol , vol.35 , pp. 851-864
    • Corder, E.H.1    Woodbury, M.A.2    Volkmann, I.3    Madsen, D.K.4    Bogdanovic, N.5    Winblad, B.6
  • 7
    • 33746825841 scopus 로고    scopus 로고
    • Corder EH, Mellcok GD. Parkinson's disease in relation to toxin exposure and mitochondrial complex I gene variants. J Biomed Biotechnol; 2006 Article ID 27601, 8 pages, 2006, in press.
  • 8
    • 33646068714 scopus 로고    scopus 로고
    • Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma
    • Corder E.H., and Hefler L.A. Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma. Rejuvenation Res 9 (2006) 56-60
    • (2006) Rejuvenation Res , vol.9 , pp. 56-60
    • Corder, E.H.1    Hefler, L.A.2
  • 9
    • 0016823810 scopus 로고
    • "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., and McHugh P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12 3 (1975) 189-198
    • (1975) J Psychiatr Res , vol.12 , Issue.3 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 10
    • 0034962808 scopus 로고    scopus 로고
    • Neuroinflammation and the genetics of Alzheimer's disease: the search for a pro-inflammatory phenotype
    • Franceschi C., Valensin S., Lescai F., Olivieri F., Licastro F., Grimaldi L.M., et al. Neuroinflammation and the genetics of Alzheimer's disease: the search for a pro-inflammatory phenotype. Aging (Milano) 13 (2001) 163-170
    • (2001) Aging (Milano) , vol.13 , pp. 163-170
    • Franceschi, C.1    Valensin, S.2    Lescai, F.3    Olivieri, F.4    Licastro, F.5    Grimaldi, L.M.6
  • 11
    • 17644438751 scopus 로고    scopus 로고
    • Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism
    • Grimaldi L.M., Casadei V.M., Ferri C., Veglia F., Licastro F., Annoni G., et al. Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism. Ann Neurol 47 (2000) 361-365
    • (2000) Ann Neurol , vol.47 , pp. 361-365
    • Grimaldi, L.M.1    Casadei, V.M.2    Ferri, C.3    Veglia, F.4    Licastro, F.5    Annoni, G.6
  • 12
    • 28644451007 scopus 로고    scopus 로고
    • Grimm MO, Grimm HS, Patzold AJ, Zinser EG, Halonen R, Duering M, et al. Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin. Nat Cell Biol; 2005.
  • 14
    • 31844451010 scopus 로고    scopus 로고
    • Anti-inflammatory effects of statins: clinical evidence and basic mechanisms
    • Jain M.K., and Ridker P.M. Anti-inflammatory effects of statins: clinical evidence and basic mechanisms. Nat Rev Drug Discov 4 (2005) 977-987
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 977-987
    • Jain, M.K.1    Ridker, P.M.2
  • 15
    • 27744532144 scopus 로고    scopus 로고
    • Pharmacogenomics of statin responsiveness
    • [Discussion 34K-35K. Epub October 21, 2005]
    • Kajinami K., Akao H., Polisecki E., and Schaefer E.J. Pharmacogenomics of statin responsiveness. Am J Cardiol 96 (2005) 65K-70K [Discussion 34K-35K. Epub October 21, 2005]
    • (2005) Am J Cardiol , vol.96
    • Kajinami, K.1    Akao, H.2    Polisecki, E.3    Schaefer, E.J.4
  • 16
    • 0036644961 scopus 로고    scopus 로고
    • Cytokines, chemokines, and cytokine receptors in human microglia
    • Lee Y.B., Nagai A., and Kim S.U. Cytokines, chemokines, and cytokine receptors in human microglia. J Neurosci Res 69 (2002) 94-103
    • (2002) J Neurosci Res , vol.69 , pp. 94-103
    • Lee, Y.B.1    Nagai, A.2    Kim, S.U.3
  • 17
    • 0037396305 scopus 로고    scopus 로고
    • Brain immune responses cognitive decline and dementia: relationship with phenotype expression and genetic background
    • Licastro F., and Chiappelli M. Brain immune responses cognitive decline and dementia: relationship with phenotype expression and genetic background. Mech Ageing Dev 124 (2003) 539-548
    • (2003) Mech Ageing Dev , vol.124 , pp. 539-548
    • Licastro, F.1    Chiappelli, M.2
  • 19
    • 0033966340 scopus 로고    scopus 로고
    • Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?
    • Licastro F., Pedrini S., Caputo L., Annoni G., Davis L.J., Ferri C., et al. Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?. J Neuroimmunol 103 (2000) 97-102
    • (2000) J Neuroimmunol , vol.103 , pp. 97-102
    • Licastro, F.1    Pedrini, S.2    Caputo, L.3    Annoni, G.4    Davis, L.J.5    Ferri, C.6
  • 20
    • 0033848463 scopus 로고    scopus 로고
    • Gene polymorphism affecting alpha1-antichymotrypsin and interleukin-1 plasma levels increases Alzheimer's disease risk
    • Licastro F., Pedrini S., Ferri C., Casadei V., Govoni M., Pession A., et al. Gene polymorphism affecting alpha1-antichymotrypsin and interleukin-1 plasma levels increases Alzheimer's disease risk. Ann Neurol 48 (2000) 388-391
    • (2000) Ann Neurol , vol.48 , pp. 388-391
    • Licastro, F.1    Pedrini, S.2    Ferri, C.3    Casadei, V.4    Govoni, M.5    Pession, A.6
  • 21
    • 0032146242 scopus 로고    scopus 로고
    • Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype
    • Licastro F., Mallory M., Hansen L.A., and Masliah E. Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype. J Neuroimmunol 88 (1998) 105-110
    • (1998) J Neuroimmunol , vol.88 , pp. 105-110
    • Licastro, F.1    Mallory, M.2    Hansen, L.A.3    Masliah, E.4
  • 22
    • 0043092123 scopus 로고    scopus 로고
    • Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain
    • Licastro F., Grimaldi L.M., Bonafe M., Martina C., Olivieri F., Cavallone L., et al. Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain. Neurobiol Aging 24 (2003) 921-926
    • (2003) Neurobiol Aging , vol.24 , pp. 921-926
    • Licastro, F.1    Grimaldi, L.M.2    Bonafe, M.3    Martina, C.4    Olivieri, F.5    Cavallone, L.6
  • 23
    • 0034898296 scopus 로고    scopus 로고
    • Genetic background of inflammatory molecules affects protein expression, the risk of developing Alzheimer's disease and cognitive decline
    • Licastro F. Genetic background of inflammatory molecules affects protein expression, the risk of developing Alzheimer's disease and cognitive decline. Arch Gerontol Geriatr Suppl 7 (2001) 227-234
    • (2001) Arch Gerontol Geriatr Suppl , vol.7 , pp. 227-234
    • Licastro, F.1
  • 24
    • 19944429724 scopus 로고    scopus 로고
    • A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease
    • Licastro F., Chiappelli M., Grimaldi L.M., Morgan K., Kalsheker N., Calabrese E., et al. A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease. Neurobiol Aging 26 (2005) 449-453
    • (2005) Neurobiol Aging , vol.26 , pp. 449-453
    • Licastro, F.1    Chiappelli, M.2    Grimaldi, L.M.3    Morgan, K.4    Kalsheker, N.5    Calabrese, E.6
  • 25
    • 0033529913 scopus 로고    scopus 로고
    • Apolipoprotein E and alpha-1-antichymotrypsin allele polymorphism in sporadic and familial Alzheimer's disease
    • Licastro F., Pedrini S., Govoni M., Pession A., Ferri C., Annoni G., et al. Apolipoprotein E and alpha-1-antichymotrypsin allele polymorphism in sporadic and familial Alzheimer's disease. Neurosci Lett 270 (1999) 129-132
    • (1999) Neurosci Lett , vol.270 , pp. 129-132
    • Licastro, F.1    Pedrini, S.2    Govoni, M.3    Pession, A.4    Ferri, C.5    Annoni, G.6
  • 26
    • 8644239495 scopus 로고    scopus 로고
    • Statin therapy and risk of dementia in the elderly: a community-based prospective cohort study
    • Li G., Higdon R., Kukull W.A., Peskind E., Van Valen Moore K., Tsuang D., et al. Statin therapy and risk of dementia in the elderly: a community-based prospective cohort study. Neurology 63 (2004) 1624-1628
    • (2004) Neurology , vol.63 , pp. 1624-1628
    • Li, G.1    Higdon, R.2    Kukull, W.A.3    Peskind, E.4    Van Valen Moore, K.5    Tsuang, D.6
  • 28
    • 0032146978 scopus 로고    scopus 로고
    • The importance of inflammatory mechanisms in Alzheimer disease
    • McGeer E.G., and McGeer P.L. The importance of inflammatory mechanisms in Alzheimer disease. Exp Gerontol 33 (1998) 371-378
    • (1998) Exp Gerontol , vol.33 , pp. 371-378
    • McGeer, E.G.1    McGeer, P.L.2
  • 29
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G., Drachman D., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34 7 (1984) 939-944
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 30
    • 19344361883 scopus 로고    scopus 로고
    • Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models
    • Morihara T., Teter B., Yang F., Lim G.P., Boudinot S., Boudinot F.D., et al. Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models. Neuropsychopharmacology 30 (2005) 1111-1120
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1111-1120
    • Morihara, T.1    Teter, B.2    Yang, F.3    Lim, G.P.4    Boudinot, S.5    Boudinot, F.D.6
  • 31
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: the cholesterol connection
    • Puglielli L., Tanzi R.E., and Kovacs D.M. Alzheimer's disease: the cholesterol connection. Nat Neurosci 6 (2003) 345-351
    • (2003) Nat Neurosci , vol.6 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 32
    • 0345830739 scopus 로고    scopus 로고
    • Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study
    • Rofecoxib Protocol 091 Study Group
    • Reines S.A., Block G.A., Morris J.C., Liu G., Nessly M.L., Lines C.R., et al., Rofecoxib Protocol 091 Study Group. Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study. Neurology 62 (2004) 66-71
    • (2004) Neurology , vol.62 , pp. 66-71
    • Reines, S.A.1    Block, G.A.2    Morris, J.C.3    Liu, G.4    Nessly, M.L.5    Lines, C.R.6
  • 33
    • 0036321773 scopus 로고    scopus 로고
    • Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study
    • Schmidt R., Schmidt H., Curb J.D., Masaki K., White L.R., and Launer L.J. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann Neurol 52 (2002) 168-174
    • (2002) Ann Neurol , vol.52 , pp. 168-174
    • Schmidt, R.1    Schmidt, H.2    Curb, J.D.3    Masaki, K.4    White, L.R.5    Launer, L.J.6
  • 34
    • 20844440894 scopus 로고    scopus 로고
    • Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results
    • Sparks D.L., Sabbagh M.N., Connor D.J., Lopez J., Launer L.J., Browne P., et al. Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results. Arch Neurol 62 (2005) 753-757
    • (2005) Arch Neurol , vol.62 , pp. 753-757
    • Sparks, D.L.1    Sabbagh, M.N.2    Connor, D.J.3    Lopez, J.4    Launer, L.J.5    Browne, P.6
  • 35
    • 9644275598 scopus 로고    scopus 로고
    • Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease
    • Sung S., Yang H., Uryu K., Lee E.B., Zhao L., Shineman D., et al. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol 165 (2004) 2197-2206
    • (2004) Am J Pathol , vol.165 , pp. 2197-2206
    • Sung, S.1    Yang, H.2    Uryu, K.3    Lee, E.B.4    Zhao, L.5    Shineman, D.6
  • 36
    • 0033772113 scopus 로고    scopus 로고
    • Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
    • Wolozin B., Kellman W., Ruosseau P., Celesia G.G., and Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57 (2000) 1439-1443
    • (2000) Arch Neurol , vol.57 , pp. 1439-1443
    • Wolozin, B.1    Kellman, W.2    Ruosseau, P.3    Celesia, G.G.4    Siegel, G.5
  • 37
    • 0016079303 scopus 로고
    • Clinical pure types as a fuzzy partition
    • Woodbury M.A., and Clive J. Clinical pure types as a fuzzy partition. J Cybernetics 4 (1974) 111-121
    • (1974) J Cybernetics , vol.4 , pp. 111-121
    • Woodbury, M.A.1    Clive, J.2
  • 38
    • 13244295723 scopus 로고    scopus 로고
    • Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study
    • Cache County Study Investigators
    • Zandi P.P., Sparks D.L., Khachaturian A.S., Tschanz J., Norton M., Steinberg M., et al., Cache County Study Investigators. Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study. Arch Gen Psychiatr 62 (2005) 217-224
    • (2005) Arch Gen Psychiatr , vol.62 , pp. 217-224
    • Zandi, P.P.1    Sparks, D.L.2    Khachaturian, A.S.3    Tschanz, J.4    Norton, M.5    Steinberg, M.6
  • 39
    • 14544306103 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study
    • MIRAGE Study Group
    • Yip A.G., Green R.C., Huyck M., Cupples L.A., Farrer L.A., and MIRAGE Study Group. Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study. BMC Geriatr 5 (2005) 2
    • (2005) BMC Geriatr , vol.5 , pp. 2
    • Yip, A.G.1    Green, R.C.2    Huyck, M.3    Cupples, L.A.4    Farrer, L.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.