Genetics of suicide: A systematic review of twin studies

Wiener Klinische Wochenschrift

Volumn 119, Issue 15-16, 2007, Pages 463-475

  Voracek, Martin ^a   Loibl, Lisa Mariella ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Genetics; Heritability; Meta analysis; Suicide; Systematic review; Twins

Indexed keywords

ARTICLE; CLINICAL TRIAL; DIZYGOTIC TWINS; GENETIC ANALYSIS; HEREDITY; HUMAN; MENTAL DISEASE; META ANALYSIS; MONOZYGOTIC TWINS; PERSONAL EXPERIENCE; RISK FACTOR; SOCIAL PSYCHOLOGY; SUICIDAL BEHAVIOR; SUICIDAL IDEATION; SUICIDE; SUICIDE ATTEMPT; SYSTEMATIC REVIEW;

CAUSE OF DEATH; DISEASES IN TWINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MENTAL DISORDERS; PHENOTYPE; POPULATION SURVEILLANCE; RISK FACTORS; SOCIAL ENVIRONMENT; SUICIDE; SUICIDE, ATTEMPTED; TWIN STUDIES AS TOPIC; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 34548522702     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00508-007-0823-2     Document Type: Article

References (118)

1. Voracek M, Sonneck G (2006) Medical and psychology students' disbelief in the inheritance of risk factors for suicide. Psychol Rep 99: 599-602
2. Kõlves K, Tran US, Voracek M (2007) Knowledge about suicide and local suicide prevalence: a comparison of Estonia and Austria. Percept Mot Skills 105: 3-7
3. Turecki G (2001) Suicidal behavior: is there a genetic predisposition? Bipolar Disord 3: 335-349
4. Baldessarini RJ, Hennen J (2004) Genetics of suicide: an overview. Harv Rev Psychiatry 12: 1-13
5. Brent DA, Mann JJ (2005) Family genetic studies, suicide, and suicidal behavior. Am J Med Genet C: Semin Med Genet 133C: 13-24
6. Joiner TE, Brown JS, Wingate LR (2005) The psychology and neurobiology of suicidal behavior. Annu Rev Psychol 56: 287-314
7. Bondy B, Buettner A, Zill P (2006) Genetics of suicide. Mol Psychiatry 11: 336-351
8. Li D, He L (2006) Further clarification of the contribution of the tryptophan hydroxylase (TPH) gene to suicidal behavior using systematic allelic and genotypic meta-analyses. Hum Genet 119: 233-240
9. Hesselbrock V, Dick D, Hesselbrock M, Foroud T, Schuckit M, Edenberg H, et al (2004) The search for genetic risk factors associated with suicidal behavior. Alcohol Clin Exp Res 28 [Suppl]: 70S-76S
10. Cheng R, Juo SH, Loth JE, Nee J, Iossifov I, Blumenthal R, et al (2006) Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder. Mol Psychiatry 11: 252-260
11. Marušič A, Farmer A (2001) Genetic risk factors as possible causes of the variation in European suicide rates [editorial]. Br J Psychiatry 179: 194-196
12. Voracek M, Fisher ML, Marušič A (2003) The Finno-Ugrian suicide hypothesis: variation in European suicide rates by latitude and longitude. Percept Mot Skills 97: 401-406
13. Voracek M, Formann AK (2004) Variation in European suicide rates is better accounted for by latitude and longitude than by national percentage of Finno-Ugrians and type 0 blood: a rebuttal of Lester and Kondrichin (2004). Percept Mot Skills 99: 1243-1250
14. Marušič A (2005) History and geography of suicide: could genetic risk factors account for the variation in suicide rates? [editorial] Am J Med Genet C: Semin Med Genet 133C: 43-47
15. Voracek M (2006) Ancestry, genes, and suicide: a test of the Finno-Ugrian Suicide Hypothesis in the United States. Percept Mot Skills 103: 543-550
16. Voracek M, Loibl LM, Kandrychyn S (2007) Testing the Finno-Ugrian Suicide Hypothesis: replication and refinement with regional suicide data from Eastern Europe. Percept Mot Skills 104: 985-994
17. Voracek M, Marušič A (2006) Testing the Finno-Ugrian Suicide Hypothesis: geographical variation of elderly suicide rates across Europe. [Ms. submitted for publication]
18. Ferrada-Noli M (1997) A cross-cultural breakdown of Swedish suicide. Acta Psychiatr Scand 96: 108-116
19. Hjern A, Allebeck P (2002) Suicide in first- and secondgeneration immigrants in Sweden: a comparative study. Soc Psychiatry Psychiatr Epidemiol 37: 423-429
20. Marušič A, Perman M, Zorko M, Kravanja M (2006) Investigating surnames of males who committed suicide in a patrilineal society [abstract]. Psychiatr Danub 18 [Suppl 1]: 140
21. Voracek M, Sonneck G (2007) Surname study of suicide in Austria: differences in regional suicide rates correspond to the genetic structure of the population. Wien Klin Wochenschr 119: 355-360
22. Tsuang MT (1977) Genetic factors in suicide. Dis Nerv Syst 38: 498-501
23. Lester D (1986) Genetics, twin studies and suicide. Suicide Life Threat Behav 16: 274-285
24. Roy A (1992) Are there genetic factors in suicide? Int Rev Psychiatry 4: 169-175
25. Roy A (1993) Genetic and biologic risk factors for suicide in depressive disorders. Psychiatric Q 64: 345-358
26. Roy A, Rylander G, Sarchiapone M (1997) Genetics of suicide: family studies and molecular genetics. Ann NY Acad Sci 836: 135-157
27. Roy A, Nielsen D, Rylander G, Sarchiapone M, Segal N (1999) Genetics of suicide in depression. J Clin Psychiatry 60 [Suppl 2]: 12-17
28. Roy A, Nielsen D, Rylander G, Sarchiapone M (2000) The genetics of suicidal behaviour. In: Hawton K, van Heeringen K (eds) The international handbook of suicide and attempted suicide. John Wiley, Chichester, pp 209-221
29. Zalsman G, Frisch A, Apter A, Weizman A (2002) Genetics of suicidal behavior: candidate association genetic approach. Isr J Psychiatry Relat Sci 39: 252-261
30. Haberlandt W (1965) Der Suizid als genetisches Problem (Zwillings- und Familienanalyse) [Suicide from the view of genetics: twin and family analyses]. Anthropolog Anz 29: 65-89
31. Haberlandt WF (1967) Aportación a la genética del suicidio: datos en gemelos y hallazgos familiares [Contribution to the genetics of suicide: data in twins and familial findings]. Folia Clin Int Barc 17: 319-322
32. Lester D (2002) Twin studies of suicidal behavior. Arch Suicide Res 6: 383-389
33. Voracek M, Formann AK, Fülöp G, Sonneck G (2003) Suicide and general elections in Austria: do preceding regional suicide rate differentials foreshadow subsequent voting behavior swings? J Affect Disord 74: 257-266
34. Voracek M (2004) National intelligence and suicide rate: an ecological study of 85 countries. Pers Individ Dif 37: 543-553
35. Voracek M (2006) Smart and suicidal? The social ecology of intelligence and suicide in Austria. Death Stud 30: 471-485
36. Dervic K, Friedrich E, Oquendo MA, Voracek M, Friedrich MH, Sonneck G (2006) Suicide in Austrian children and young adolescents ages 14 and younger. Eur Child Adolesc Psychiatry 15: 427-434
37. Dervic K, Friedrich E, Prosquill D, Kapusta ND, Lenz G, Sonneck G, Friedrich MH (2006) Suicide among Viennese minors, 1946-2002. Wien Klin Wochenschr 118: 152-159
38. Etzersdorfer E, Kapusta ND, Sonneck G (2006) Suicide by shooting is correlated to rate of gun licenses in Austrian counties. Wien Klin Wochenschr 118: 464-468
39. Etzersdorfer E, Voracek M, Kapusta N, Sonneck G (2005) Epidemiology of suicide in Austria 1990-2000: general decrease, but increased suicide risk for old men. Wien Klin Wochenschr 117: 31-35
40. Friedrich MH (2006) Suizid im Kindes- und Jugendalter [Suicide in children and adolescents]. Wien Klin Wochenschr 118: 131-133
41. Leenaars AA (2006) Suicide by shooting and gun ownership (licenses) in Austria: would gun restriction help? Wien Klin Wochenschr 118: 439-441
42. Ritter K, Stompe T, Voracek M, Etzersdorfer E (2002) Suicide risk-related knowledge and attitudes of general practitioners. Wien Klin Wochenschr 114: 685-690
43. Allen G, Harvald B, Shields J (1967) Measures of twin concordance. Acta Genet Stat Med 17: 475-481
44. Smith C (1974) Concordance in twins: methods and interpretation. Am J Hum Genet 26: 454-466
45. Mellon CD (1996) Hereditary madness: the evolution of psychiatric genetic thought. Genetics Heritage Press, Placitas (NM), pp 48-49, 96, 120-121
46. Cho H, Guo G, Iritani BJ, Hallfors DD (2006) Genetic contribution to suicidal behaviors and associated risk factors among adolescents in the U.S. Prev Sci 7: 303-311
47. Holzinger KJ (1929) The relative effect of nature and nurture influences on twin differences. J Educ Psychol 20: 241-248
48. Borenstein M, Hedges L, Higgins J, Rothstein H (2005) Comprehensive Meta-Analysis, Version 2 [computer software]. Biostat, Englewood (NJ)
49. Rush B (1812) Medical inquiries and observations, upon the diseases of the mind. Kimber, Philadelphia
50. Loewenberg RD (1941) Suicide in twins: a historical note. J Nerv Ment Dis 93: 182-184
51. Baume (1863) Singulier cas de folie suicide chez deux frères jumeaux: coïncidence bizarre [A unique case of suicidal insanity among two twin brothers: a bizarre coincidence]. Ann Med Psychol Paris: 312-313
52. Smith P (1912) Psychoses occurring in twins. NY Med J 12: 1268-1272
53. Soukhanoff S (1912) De la soi-disant folie gémellaire [About the so-called twin insanity]. Revue de Psychiatrie et de Psychologie Expérimentale 16: 486-492
54. Soukhanoff S (1900) Sur la folie gémellaire [About twin insanity]. Ann Med Psychol 2: 214-231
55. Le Gras AM (1932) Psychose en criminaliteit bij tweelingen [Psychosis and criminality in twins]. Kemink, Utrecht (The Netherlands)
56. Le Gras AM (1933) Psychose und Kriminalität bei Zwillingen [Psychosis and criminality in twins]. Zeitschrift für die gesamte Neurologie und Psychiatrie 144: 198-221
57. Menninger KA (1938) Man against himself. George G. Harrap, London
58. Hanhart E (1968/69) Zur Frage der Beteiligung genetischer Faktoren bei Selbstmorden anhand von temporären Häufungen familiärer Suizide in Schweizer Isolaten [On the question of a contribution of genetic factors in suicide based on temporary increases in the rate of familial suicides in Swiss isolates]. Arch Julius Klaus Stift Vererbungsforsch Sozialanthropol Rassenhyg 43-44: 305-376
59. Gedda L (1951) Studio dei gemelli [Twin studies]. Edizioni Orizzonte Medico, Roma
60. Vogt A, Wagner H, Richner H, Meyer G (1939) Das Senium bei eineiigen und zweieiigen Zwillingen: Die Erbentstehung bisher exogen und durch "Abnützung" erklärter Altersleiden [Old age in monozygotic and dizygotic twins: on the inheritance of late-onset diseases previously explained environmentally and through depletion]. Arch Julius Klaus Stift Vererbungsforsch Sozialanthropol Rassenhyg 14: 475-597
61. von Verschuer O (1954) Wirksame Faktoren im Leben des Menschen: Beobachtungen an ein- und zweieiigen Zwillingen durch 25 Jahre [Influential factors over the human life cycle: observations on monozygotic and dizygotic twins over 25 years]. Franz Steiner, Wiesbaden (Germany)
62. Koch G (1957) Ergebnisse aus der Nachuntersuchung der Berliner Zwillingsserie nach 20-25 Jahren (vorläufige Ergebnisse) [Follow-up results from the Berlin twin series after 20-25 years (preliminary findings)]. Acta Genet 7: 47-52
63. Swanson DW (1960) Suicide in identical twins. Am J Psychiatry 115: 934-935
64. Wilson IC, Reece JC (1964) Simultaneous death in schizophrenic twins. Arch Gen Psychiatry 11: 377-384
65. Berger H (1964) Manisch-depressive Psychosen bei eineiigen Zwillingen [Manic-depressive psychoses in monozygotic twins]. Medical dissertation, University of Munich (Germany)
66. Blath R, McClure J, Wetzel R (1973) Familial factors in suicide. Dis Nerv Syst 34: 90-93
67. Zaw KM (1981) A suicidal family. Br J Psychiatry 139: 68-69
68. Kallmann FJ, Anastasio M (1946) Twin studies on the psychopathology of suicide. J Hered 37: 171-180
69. Kallmann FJ, Anastasio MM (1947) Twin studies on the psychopathology of suicide. J Nerv Ment Dis 105: 40-55
70. Kallmann FJ, De Porte J, De Porte E, Feingold L (1949) Suicide in twins and only children. Am J Hum Genet 1: 113-126
71. Kallmann FJ (1953) Heredity in health and mental disease: principles of psychiatric genetics in the light of comparative twin studies. Norton, New York
72. Lester D (1968) Note on the inheritance of suicide. Psychol Rep 22: 320
73. Bertelsen A, Harvald B, Hauge M (1977) A Danish twin study of manic-depressive disorders. Br J Psychiatry 130: 330-351
74. Harvald B, Hauge M (1965) Hereditary factors elucidated by twin studies. In: Neel JV, Shaw MW, Schull WJ (eds) Genetics and the epidemiology of chronic disease. U.S. Department of Health, Education, and Welfare, Washington (DC), pp 61-76
75. Hauge M, Harvald B, Fischer M, Gotlieb-Jensen K, Juel-Nielsen N, Raebild I, et al (1968) The Danish twin register. Acta Genet Med Gemellol Roma 17: 315-331
76. Juel-Nielsen N, Videbech T (1970) A twin study of suicide. Acta Genet Med Gemellol Roma 19: 307-310
77. Juel-Nielsen N (1979) Suicide risk in manic-depressive disorders. In: Schou M, Strömgren E (eds) Origin, prevention and treatment of affective disorders. Academic Press, London, pp 269-276
78. Roy A, Segal NL, Centerwall BS, Robinette CD (1991) Suicide in twins. Arch Gen Psychiatry 48: 29-32
79. Segal NL, Bouchard TJ (1993) Grief intensity following the loss of a twin and other relatives: test of kinship genetic hypotheses. Hum Biol 65: 87-105
80. Segal NL, Wilson SM, Bouchard TJ, Gitlin D (1995) Comparative grief experiences of bereaved twins and other bereaved relatives. Pers Individ Dif 18: 511-524
81. McGuffin P, Marušič A, Farmer A (2001) What can psychiatric genetics offer suicidology? Crisis 22: 61-65
82. Roy A, Segal NL (2001) Suicidal behavior in twins: a replication. J Affect Disord 66: 71-74
83. Kaprio J, Romanov K, Lönnqvist J, Koskenvuo M (1995) Suicide in twins: the Finnish twin cohort study [abstract]. Psychiatr Genet 5: S102
84. Statham DJ, Heath AC, Madden PAF, Bucholz KK, Bierut L, Dinwiddie SH, et al (1998) Suicidal behavior: an epidemiological and genetic study. Psychol Med 28: 839-855
85. Fu Q, Heath AC, Bucholz KK, Nelson EC, Glowinski AL, Goldberg J, et al (2002) A twin study of genetic and environmental influences on suicidality in men. Psychol Med 32: 11-24
86. Glowinski AL, Bucholz KK, Nelson EC, Fu Q, Madden PA, Reich W, Health AC (2001) Suicide attempts in an adolescent female twin sample. J Am Acad Child Adolesc Psychiatry 40: 1300-1307
87. Roy A, Segal NL, Sarchiapone M (1995) Attempted suicide among living co-twins of twin suicide victims. Am J Psychiatry 152: 1075-1076
88. Roy A, Rylander G, Forslund K, Asberg M, Mazzanti CM, Goldman D, Nielsen DA (2001) Excess tryptophan hydroxylase 17 779C allele in surviving cotwins of monozygotic twin suicide victims. Neuropsychobiology 43: 233-236
89. Voracek M, Tran US (2007) Dietary tryptophan intake and suicide rate in industrialized nations. J Affect Disord 98: 259-262
90. Segal NL, Roy A (1995) Suicide attempts in twins whose co-twins deaths were non-suicides. Pers Individ Dif 19: 937-940
91. Pompili M, Galeandro PM, Lester D, Tatarelli R (2006) Suicidal behavior in surviving co-twins. Twin Res Hum Genet 9: 642-645
92. Segal N, Roy A (2001) Suicidal attempts and ideation in twins whose co-twin deaths were non-suicides: replication and extension. Pers Individ Dif 31: 445-452
93. Newman HH, Freeman FH, Holzinger KJ (1937) Twins: a study of heredity and environment. University of Chicago Press, Chicago
94. Bouchard TJ, Lykken DT, McGue M, Segal NL, Tellegen A (1990) Sources of human psychological differences: the Minnesota Study of Twins Reared Apart. Science 250: 223-228
95. Shields J (1962) Monozygotic twins, brought up apart and brought up together: an investigation into the genetic and environmental causes of variation in personality. Oxford University Press, London
96. Juel-Nielsen N (1965) Individual and environment: a psychiatric- psychological investigation of monozygotic twins reared apart. Acta Psychiatr Scand [Suppl 183]: 1-158, 1-292
97. Pedersen NL, Plomin R, Nesselroade JR, McClearn GE (1992) A quantitative genetic analysis of cognitive abilities during the second half of the life span. Psychol Sci 3: 346-353
98. Langinvainio H, Koskenvuo M, Kaprio J, Sistonen P (1984) Finnish twins reared apart. II: validation of zygosity, environmental dissimilarity and weight and height. Acta Genet Med Gemellol Roma 33: 251-258
99. Burt C (1966) Genetic determination of differences in intelligence: a study of monozygotic twins reared together and apart. Br J Psychol 57: 137-153
100. Hearnshaw LS (1979) Cyril Burt: psychologist. Cornell University Press, Ithaca (NY)
101. Joynson RB (1989) The Burt affair. Routledge, London
102. Fletcher R (1991) Science, ideology, and the media: the Cyril Burt scandal. Transaction Publishers, New Brunswick (NJ)
103. Rushton JP (2002) New evidence on Sir Cyril Burt: his 1964 speech to the Association of Educational Psychologists. Intelligence 30: 555-567
104. Burbridge D (2006) Burt's twins: a question of numbers. J Hist Behav Sci 42: 335-352
105. Spaeth J (1860) Studien über Zwillinge [Twin studies]. Zeitschrift der Wiener Gesellschaft der Ärzte 16: 225-231, 241-244
106. Spaeth J (1862) Studies regarding twins. Edinburgh Med J 7: 841-849
107. Kleinwächter L (1871) Die Lehre von den Zwillingen [Twin studies]. Haerpfer, Prague
108. Galton F (1875) The history of twins, as a criterion of the relative powers of nature and nurture. J Anthropol Inst 5: 391-406
109. Siemens HW (1924) Die Zwillingspathologie: ihre Bedeutung, ihre Methodik, ihre bisherigen Ergebnisse [The twin pathology: its relevance, method, and results so far]. Springer, Berlin
110. Holland T, Gosden C (1990) A balanced chromosomal translocation partially co-segregating with psychotic illness in a family. Psychiatry Res 32: 1-8
111. Weinberg W (1927) Mathematische Grundlagen der Probandenmethode [Mathematical foundations of the proband method]. Z Indukt Abstamm Vererbungsl 48: 179-228
112. Strömgren E (1935) Zum Ersatz des Weinbergschen "abgekü rzten Verfahrens": zugleich ein Beitrag zur Frage von der Erblichkeit des Erkrankungsalters bei der Schizophrenie [On the substitution of Weinberg's abbreviated procedure: concomitantly a contribution to the question of age-of-onset heritability in schizophrenia]. Zeitschrift für die gesamte Neurologie und Psychiatrie 153: 784-797
113. Slater E (1953) Psychotic and neurotic illnesses in twins. Her Majesty's Stationary Office, London
114. Tomassini C, Juel K, Holm NV, Skytthe A, Christensen K (2003) Risk of suicide in twins: 51 year follow up study. Br Med J 327: 373-374
115. Voracek M (2003) Risk of suicide in twins: intelligence of twins and singletons may explain risk [letter]. Br Med J 327: 1168
116. Bostwick JM, Pankratz VS (2000) Affective disorders and suicide risk: a reexamination. Am J Psychiatry 157: 1925-1932
117. Tariverdian G, Buselmaier W (2004) Humangenetik [Human genetics], 3rd, rev. edn. Springer, Berlin, p 371
118. Haberlandt WF (2003) Rückblick eines Wissenschaftlers - Bekenntnis eines Zeitzeugen: 1921-2001 [Memoirs of a scientist - confessions of a contemporary witness: 1921-2001]. VGB-Verlagsgesellschaft, Inning am Ammersee (Germany)