-
1
-
-
0037667643
-
Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation
-
Carey R.M., and Siragy H.M. Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation. Endocr Rev 24 (2003) 261-271
-
(2003)
Endocr Rev
, vol.24
, pp. 261-271
-
-
Carey, R.M.1
Siragy, H.M.2
-
2
-
-
33646501526
-
Renin/prorenin receptors
-
Nguyen G. Renin/prorenin receptors. Kidney Int 69 (2006) 1503-1506
-
(2006)
Kidney Int
, vol.69
, pp. 1503-1506
-
-
Nguyen, G.1
-
3
-
-
33846996406
-
The (pro)renin receptor: pathophysiological roles in cardiovascular and renal pathology
-
Nguyen G. The (pro)renin receptor: pathophysiological roles in cardiovascular and renal pathology. Curr Opin Nephrol Hypertens 16 (2007) 129-133
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 129-133
-
-
Nguyen, G.1
-
5
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
-
Nguyen G., Delarue F., Burcklé C., et al. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109 (2002) 1417-1427
-
(2002)
J Clin Invest
, vol.109
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burcklé, C.3
-
6
-
-
0021889169
-
Increased plasma inactive renin in diabetes mellitus a marker of microvascular complications
-
Luetscher J.A., Kraemer F.B., Wilson D.M., et al. Increased plasma inactive renin in diabetes mellitus a marker of microvascular complications. N Engl J Med 312 (1985) 1412-1417
-
(1985)
N Engl J Med
, vol.312
, pp. 1412-1417
-
-
Luetscher, J.A.1
Kraemer, F.B.2
Wilson, D.M.3
-
7
-
-
0029858320
-
Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver
-
Véniant M., Ménard J., Bruneval P., et al. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest 98 (1996) 1966-1970
-
(1996)
J Clin Invest
, vol.98
, pp. 1966-1970
-
-
Véniant, M.1
Ménard, J.2
Bruneval, P.3
-
8
-
-
0033553522
-
In vivo enzymatic assay reveals catalytic activity of the human renin precursor in tissues
-
Methot D., Silversides D.W., and Reudelhuber T.L. In vivo enzymatic assay reveals catalytic activity of the human renin precursor in tissues. Circ Res 84 (1999) 1067-1072
-
(1999)
Circ Res
, vol.84
, pp. 1067-1072
-
-
Methot, D.1
Silversides, D.W.2
Reudelhuber, T.L.3
-
9
-
-
33646121749
-
Prorenin: back into the arena
-
Danser A.H. Prorenin: back into the arena. Hypertension 47 (2006) 824-826
-
(2006)
Hypertension
, vol.47
, pp. 824-826
-
-
Danser, A.H.1
-
10
-
-
33750600468
-
Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system
-
Nabi A.H., Kageshima A., Uddin M.N., et al. Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 18 (2006) 483-488
-
(2006)
Int J Mol Med
, vol.18
, pp. 483-488
-
-
Nabi, A.H.1
Kageshima, A.2
Uddin, M.N.3
-
11
-
-
0024538619
-
Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution
-
Sielecki A.R., Hayakawa K., Fujinaga M., et al. Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. Science 243 (1989) 1346-1351
-
(1989)
Science
, vol.243
, pp. 1346-1351
-
-
Sielecki, A.R.1
Hayakawa, K.2
Fujinaga, M.3
-
12
-
-
0029004117
-
Molecular analysis of human prorenin prosegment variants in vitro and in vivo
-
Mercure C., Thibault G., Lussier-Cacan S., et al. Molecular analysis of human prorenin prosegment variants in vitro and in vivo. J Biol Chem 270 (1995) 16355-16359
-
(1995)
J Biol Chem
, vol.270
, pp. 16355-16359
-
-
Mercure, C.1
Thibault, G.2
Lussier-Cacan, S.3
-
13
-
-
0037591344
-
Human prorenin has "gate and handle" regions for its non-proteolytic activation
-
Suzuki F., Hayakawa M., Nagakawa T., et al. Human prorenin has "gate and handle" regions for its non-proteolytic activation. J Biol Chem 278 (2003) 22217-22222
-
(2003)
J Biol Chem
, vol.278
, pp. 22217-22222
-
-
Suzuki, F.1
Hayakawa, M.2
Nagakawa, T.3
-
14
-
-
9644283069
-
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin
-
Ichihara A., Hayashi M., Kaneshiro Y., et al. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J Clin Invest 114 (2004) 1128-1135
-
(2004)
J Clin Invest
, vol.114
, pp. 1128-1135
-
-
Ichihara, A.1
Hayashi, M.2
Kaneshiro, Y.3
-
15
-
-
33646160993
-
Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
-
Ichihara A., Kaneshiro Y., Takemitsu T., et al. Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 47 (2006) 894-900
-
(2006)
Hypertension
, vol.47
, pp. 894-900
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
-
16
-
-
33748044643
-
Contribution of nonprotelolytically activated prorenin in glomeruli of hypertensive renal damage
-
Ichihara A., Kaneshiro Y., Takemitsu T., et al. Contribution of nonprotelolytically activated prorenin in glomeruli of hypertensive renal damage. J Am Soc Nephrol 17 (2006) 2495-2503
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2495-2503
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
-
17
-
-
33745674108
-
Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting non-proteolytic activation of prorenin
-
Satofuka S., Ichihara A., Nagai N., et al. Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting non-proteolytic activation of prorenin. Invest Ophthalmol Vis Sci 47 (2006) 2686-2692
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 2686-2692
-
-
Satofuka, S.1
Ichihara, A.2
Nagai, N.3
-
18
-
-
33745824649
-
Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
-
Ichihara A., Suzuki F., Nakagawa T., et al. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice. J Am Soc Nephrol 17 (2006) 1950-1961
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1950-1961
-
-
Ichihara, A.1
Suzuki, F.2
Nakagawa, T.3
-
19
-
-
33750274126
-
Prorenin receptor blockers: effects on cardiovascular complications of diabetes and hypertension
-
Ichihara A., Kaneshiro Y., and Suzuki F. Prorenin receptor blockers: effects on cardiovascular complications of diabetes and hypertension. Expert Opin Investig Drugs 15 (2006) 1137-1139
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 1137-1139
-
-
Ichihara, A.1
Kaneshiro, Y.2
Suzuki, F.3
-
20
-
-
33748031509
-
Regulation of the renal renin/(pro)renin receptor by ACE-inhibition and sodium restriction
-
Hamming I., Contrepas A., Nguyen G., et al. Regulation of the renal renin/(pro)renin receptor by ACE-inhibition and sodium restriction. J Am Soc Nephrol 16 (2005) 120
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 120
-
-
Hamming, I.1
Contrepas, A.2
Nguyen, G.3
-
21
-
-
33845608395
-
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
-
Schefe J.H., Menk M., Reinemund J., et al. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 99 (2006) 1355-1366
-
(2006)
Circ Res
, vol.99
, pp. 1355-1366
-
-
Schefe, J.H.1
Menk, M.2
Reinemund, J.3
-
22
-
-
34447287846
-
Renin and its putative receptor remain enigmas
-
Luft F.C. Renin and its putative receptor remain enigmas. J Am Soc Nephrol 18 (2007) 1989-1992
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1989-1992
-
-
Luft, F.C.1
-
23
-
-
0029853814
-
Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen
-
Nguyen G., Delarue F., Berrou J., et al. Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int 50 (1996) 1897-1903
-
(1996)
Kidney Int
, vol.50
, pp. 1897-1903
-
-
Nguyen, G.1
Delarue, F.2
Berrou, J.3
-
24
-
-
30944469631
-
Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
-
Huang Y., Wongamorntham S., Kasting J., et al. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 69 (2006) 105-113
-
(2006)
Kidney Int
, vol.69
, pp. 105-113
-
-
Huang, Y.1
Wongamorntham, S.2
Kasting, J.3
-
25
-
-
34347350179
-
Renin stimulated TGF-β1 expression is regulated by a mitogen-activated protein kinase in mesangial cells
-
Huang Y., Noble N., Zhang J., et al. Renin stimulated TGF-β1 expression is regulated by a mitogen-activated protein kinase in mesangial cells. Kidney Int 72 (2007) 45-52
-
(2007)
Kidney Int
, vol.72
, pp. 45-52
-
-
Huang, Y.1
Noble, N.2
Zhang, J.3
-
26
-
-
33750266798
-
Prorenin induces intracellular signalling in cardiomyocytes independently of angiotensin II
-
Saris J.J., 't Hoen P.A.C., Garrelds I.M., et al. Prorenin induces intracellular signalling in cardiomyocytes independently of angiotensin II. Hypertension 48 (2006) 1-8
-
(2006)
Hypertension
, vol.48
, pp. 1-8
-
-
Saris, J.J.1
't Hoen, P.A.C.2
Garrelds, I.M.3
-
27
-
-
33644983896
-
Elevated blood pressure and heart rate in human renin receptor transgenic rats
-
Burcklé C.A., Danser A.H.J., Müller D.N., et al. Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 47 (2006) 552-556
-
(2006)
Hypertension
, vol.47
, pp. 552-556
-
-
Burcklé, C.A.1
Danser, A.H.J.2
Müller, D.N.3
-
28
-
-
33747060126
-
Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
-
Kaneshiro Y., Ichihara A., Takemitsu T., et al. Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 70 (2006) 641-646
-
(2006)
Kidney Int
, vol.70
, pp. 641-646
-
-
Kaneshiro, Y.1
Ichihara, A.2
Takemitsu, T.3
-
29
-
-
4444220604
-
Identification of 315 genes essential for early zebrafish development
-
Amsterdam A., Nissen R.M., Sun Z., et al. Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci U S A 101 (2004) 12792-12797
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12792-12797
-
-
Amsterdam, A.1
Nissen, R.M.2
Sun, Z.3
-
30
-
-
20244369597
-
A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor
-
Ramser J., Abidi F.E., Burckle C.A., et al. A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor. Hum Mol Genet 14 (2005) 1019-1027
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1019-1027
-
-
Ramser, J.1
Abidi, F.E.2
Burckle, C.A.3
-
31
-
-
33750273175
-
On the relationship between the renin receptor and the vacuolar proton ATPase membrane sector-associated protein (M8.9)
-
Frohlich E.D., and Re R.N. (Eds), Springer Science + Business Media, New York, NY
-
L'Huillier N., Sharp M.G.F., Dunbar D.R., and Mullins J.J. On the relationship between the renin receptor and the vacuolar proton ATPase membrane sector-associated protein (M8.9). In: Frohlich E.D., and Re R.N. (Eds). The Local Cardiac Renin-Angiotensin-Aldosterone System (2006), Springer Science + Business Media, New York, NY 17-34
-
(2006)
The Local Cardiac Renin-Angiotensin-Aldosterone System
, pp. 17-34
-
-
L'Huillier, N.1
Sharp, M.G.F.2
Dunbar, D.R.3
Mullins, J.J.4
-
32
-
-
0032079560
-
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules
-
Ludwig J., Kerscher S., Brandt U., et al. Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. J Biol Chem 273 (1998) 10939-10947
-
(1998)
J Biol Chem
, vol.273
, pp. 10939-10947
-
-
Ludwig, J.1
Kerscher, S.2
Brandt, U.3
-
33
-
-
33750592956
-
Prorenin and its ancient receptor
-
Burckle C., and Bader M. Prorenin and its ancient receptor. Hypertension 48 (2006) 549-551
-
(2006)
Hypertension
, vol.48
, pp. 549-551
-
-
Burckle, C.1
Bader, M.2
-
34
-
-
0033577692
-
Substituted piperidines-highly potent renin inhibitors due to induced fit adaptation of the active site
-
Vieira E., Binggeli A., Breu V., Bur D., Fischli W., Guller R., et al. Substituted piperidines-highly potent renin inhibitors due to induced fit adaptation of the active site. Bioorg Med Chem Lett 9 (1999) 1397-1402
-
(1999)
Bioorg Med Chem Lett
, vol.9
, pp. 1397-1402
-
-
Vieira, E.1
Binggeli, A.2
Breu, V.3
Bur, D.4
Fischli, W.5
Guller, R.6
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