Dynamic interaction between medial prefrontal cortex and nucleus accumbens as a function of both motivational state and reinforcer magnitude: A c-Fos immunocytochemistry study

Brain Research

Volumn 1169, Issue 1, 2007, Pages 69-76

  Moscarello, Justin M ^a   Ben Shahar, Osnat ^a   Ettenberg, Aaron ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Food deprivation; Food reinforcement; Motivation; Nucleus accumbens; Prefrontal cortex; Rat

Indexed keywords

PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; FOOD DEPRIVATION; IMMUNOCYTOCHEMISTRY; MALE; MOTIVATION; NEUROANATOMY; NEUROCHEMISTRY; NEUROPHYSIOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DETERMINATION; PSYCHOPHYSIOLOGY; RAT; REINFORCEMENT;

ANIMALS; APPETITE; CELL COUNT; CONDITIONING, OPERANT; EATING; FOOD DEPRIVATION; IMMUNOHISTOCHEMISTRY; MALE; MOTIVATION; NEOSTRIATUM; NEURAL PATHWAYS; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT (PSYCHOLOGY); UP-REGULATION;

ANIMALIA; RATTUS;

EID: 34548489128     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.06.064     Document Type: Article

References (46)

1. Baldwin A.E., Sadeghian K., and Kelley A.E. Appetitive instrumental learning requires coincident activation of NMDA and dopamine D1 receptors within the medial prefrontal cortex. J. Neurosci. 22 (2002) 1063-1071
2. Bassareo V., and DiChiara G. Differential influence of associative and nonassociative mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. J. Neurosci. 17 (1997) 851-861
3. Bassareo V., DeLuca M.A., and DiChiara G. Differential expression of motivational stimulus properties by dopamine in nucleus accumbens shell versus core and prefrontal cortex. J. Neurosci. 22 (2002) 4709-4719
4. Ben-Shahar O., Ahmed S.H., Koob G.F., and Ettenberg A. The transition from controlled to compulsive drug use is associated with a loss of sensitization. Brain Res. 995 (2004) 46-54
5. Berendse H.W., Galis-de Graaf Y., and Groenewegen H.J. Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat. J. Comp. Neurol. 316 (1992) 314-347
6. Cagniard B., Balsam P.D., Brunner D., and Zhuang X. Mice with chronically elevated dopamine exhibit enhanced motivation, but not learning, for a food reward. Neuropsychopharmacology 31 (2006) 1362-1370
7. Carlson J.N., Herrick K.F., Baird J.L., and Glick S.D. Selective enhancement of dopamine utilization in the prefrontal cortex by food deprivation. Brain Res. 400 (1987) 200-203
8. Carlson J.N., Glick S.D., Hinds P.A., and Baird J.L. Food deprivation alters dopamine utilization in the rat prefrontal cortex and asymmetrically alters amphetamine-induced rotational behavior. Brain Res. 454 (1988) 373-377
9. Carr D.B., and Sesack S.R. Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with messoaccumbens and mesocortical neurons. J. Neurosci. 20 (2000) 3864-3873
10. Cole D.G., Kobierski L.A., Konradi C., and Hyman S.E. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 9631-9635
11. Corbit L.H., and Balleine B.W. The role of prelimbic cortex in instrumental conditioning. Behav. Brain Res. 146 (2003) 145-157
12. Dalta K.P., Ahier R.G., Young A.M.J., Gray J.A., and Joseph M.H. Conditioned appetitive stimulus increases dopamine in the nucleus accumbens of the rat. Eur. J. Neurosci. 16 (2002) 1987-1993
13. Doherty M.D., and Gratton A. Medial prefrontal cortex D1 receptor modulation of the meso-accumbens response to stress: an electrochemical study in freely behaving rats. Brain Res. 715 (1996) 86-97
14. Duvachelle C.L., Levitin L.A., MacConell M., Lee L.K., and Ettenberg A. Opposite effects of prefrontal cortex and nucleus accumbens infusions of flupenthixol on stimulant-induced locomotion and brain stimulation reward. Brain Res. 576 (1992) 104-110
15. Duvachelle C.L., Fleming S.M., and Kornetsky C. Prefrontal cortex infusions of SCH 23390 cause immediate and delayed effects on ventral tegmental area stimulation reward. Brain Res. 811 (1998) 57-62
16. Gabbott P.L.A., Warner T.A., Jays P.R.L., Salway P., and Busby S.J. Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. J. Comp. Neurol. 492 (2005) 145-177
17. Graybiel A.M., Moratalla R., and Robertson H.A. Amphetamine and cocaine induce drug specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 6912-6916
18. Horvitz J.C. Dopamine gating of glutamatergic sensorimotor and incentive motivational input signals to the striatum. Behav. Brain Res. 137 (2002) 65-74
19. Jackson M.E., Frost A.S., and Moghaddam B. Stimulation of prefrontal cortex at physiologically relevant frequencies inhibits dopamine release in the nucleus accumbens. J. Neurochem. 78 (2001) 920-923
20. Joseph M.H., Dalta K., and Young A.M.J. The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis. Neurosci. Biobehav. Rev. 27 (2003) 527-541
21. Lindvall O., Bjorklund A., Moore R.Y., and Stenevi U. Mesencephalic dopamine neurons projecting to neocortex. Brain Res. 81 (1974) 325-331
22. Ljungberg T., Apicella P., and Schultz W. Responses of monkey dopamine neurons during learning of behavioral reactions. J. Neurophysiol. 67 (1992) 145-163
23. Mitchell J.B., and Gratton A. Partial dopamine depletion of the prefrontal cortex leads to enhanced mesolimbic dopamine release elicited by repeated exposure to naturally reinforcing stimuli. J. Neurosci. 12 (1992) 3609-3618
24. Morgan J.L., and Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu. Rev. Neurosci. 14 (1991) 421-451
25. Moratalla R., Robertson H.A., and Graybiel A.M. Dynamic regulation of NGFI-A (zif 268, egr1) gene expression in the striatum. J. Neurosci. 12 (1992) 2609-2622
26. Nguyen T.V., Kosofsky B., Birnbaum R., Cohen B.M., and Hyman S.E. Differential expression of c-fos and zif 268 in rat striatum after haloperidol, clozapine and amphetamine. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 4270-4274
27. O'Donnell P., and Grace A.A. Synaptic interactions among excitatory afferents to nucleus accumbens neurons: hippocampal gating of prefrontal cortical input. J. Neurosci. 84 (1995) 3622-3639
28. Olausson P., Jentsch J.D., Tronson N., Neve R.L., Nestler E.J., and Taylor J.R. DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. J. Neurosci. 26 (2006) 9196-9204
29. Ostlund S.B., and Balleine B.W. Lesions of medial prefrontal cortex disrupt the acquisition but not the expression of goal-directed learning. J. Neurosci. 25 (2005) 7763-7770
30. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 4th ed. (1998), Academic Press, San Diego
31. Richardson N.R., and Gratton A. Changes in medial prefrontal dopamine levels associated with response-contingent food reward: an electrochemical study in rat. J. Neurosci. 18 (1996) 9130-9138
32. Roitman M.F., Wheeler R.A., and Carelli R.M. Nucleus accumbens neurons are innately tuned for rewarding and aversive taste stimuli, encode their predictors, and are linked to motor output. Neuron 45 (2005) 587-597
33. Room P., Russchen F.T., Goenewegen H.J., and Lohman A.H.M. Efferent connections of the prelimbic (area 32) and the infralimbic (area 25) cortices: an anterograde tracing study in the cat. J. Comp. Neurol. 242 (1985) 40-55
34. Satoh T., Nakai S., Sato T., and Kimura M. Correlated coding of motivation and outcome of decision by dopamine neurons. J. Neurosci. 23 (2003) 9913-9923
35. Sesack S.R., Carr D.B., Omelchenko N., and Pinto A. Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions. Ann. N.Y. Acad. Sci. 1003 (2003) 36-52
36. Schultz W. Responses of midbrain dopamine neurons to behavioral trigger stimuli in the monkey. J. Neurophysiol. 56 (1986) 1439-1461
37. Schultz W. Neural coding of basic reward terms of animal learning theory, game theory, microeconomics and behavioural ecology. Curr. Opin. Neurobiol. 14 (2004) 139-147
38. Schultz W. Behavioral theories and the neurophysiology of reward. Annu. Rev. (2006) 57
39. Schultz W., Apicella P., Scarnati E., and Ljungberg T. Neuronal activity in monkey ventral striatum related to the expectation of reward. J. Neurosci. 18 (1992) 4595-4610
40. Sheng M., and Greenberg M.E. The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4 (1992) 477-485
41. Thompson T.L., and Moss R.L. In vivo stimulated DA release in the nucleus accumbens: modulation by the prefrontal cortex. Brain Res. 686 (1995) 93-98
42. Tolman E.C., and Gleitman H. Studies in spatial learning; place and response learning under different degrees of motivation. J. Exp. Psychol. 39 (1949) 6539
43. Tzschentke T.M. Pharmacology and behavioral pharmacology of the mesocortical dopamine system. Prog. Neurobiol. 63 (2001) 241-320
44. Vanhoutte P., Barnier J.V., Guibert B., Pages C., Besson M.J., Hipskind R.A., and Caboche J. Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices. Mol. Cell. Biol. 19 (1999) 136-146
45. Xia Z., Dudek H., Miranti C.K., and Greenberg M.E. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J. Neurosci. 16 (1996) 5425-5436
46. Yun I.A., Wakabayashi K.T., Fields H.L., and Nicola S.M. The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues. J. Neurosci. 24 (2004) 2923-2933