Drug-induced liver injury: Review article

Digestive Diseases and Sciences

Volumn 52, Issue 10, 2007, Pages 2463-2471

  Bleibel, Wissam ^a   Kim, Stephen ^b   D'Silva, Karl ^a   Lemmer, Eric R ^c  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Drug induced liver injury; Hepatotoxicity

Indexed keywords

ACETYLCYSTEINE; ALKALINE PHOSPHATASE; ALLOPURINOL; AMIODARONE; AMOXICILLIN PLUS CLAVULANIC ACID; AZATHIOPRINE; BUSULFAN; CARBAMAZEPINE; CHLORPROMAZINE; CYCLOPHOSPHAMIDE; DICLOFENAC; DILTIAZEM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROMYCIN; ESTROGEN; ISONIAZID; METHOTREXATE; METHYLDOPA; MINOCYCLINE; NITROFURANTOIN; PARACETAMOL; PHENYTOIN; PROCAINAMIDE; PROPYLTHIOURACIL; QUINIDINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TAMOXIFEN; TRAZODONE; UNINDEXED DRUG; VALPROIC ACID;

ACUTE HEPATITIS; CHOLESTASIS; CHRONIC HEPATITIS; DIET THERAPY; DRUG INDUCED DISEASE; DRUG MECHANISM; DRUG OVERDOSE; FATTY LIVER; GRANULOMATOUS HEPATITIS; HISTOPATHOLOGY; HUMAN; INCIDENCE; LIVER CIRRHOSIS; LIVER FAILURE; LIVER FIBROSIS; LIVER FUNCTION TEST; LIVER INJURY; LIVER TOXICITY; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PRURITUS; REVIEW; VITAMIN K DEFICIENCY;

HUMANS; INCIDENCE; LIVER; LIVER DISEASES; LIVER FUNCTION TESTS; PHARMACEUTICAL PREPARATIONS; SURVIVAL RATE; UNITED STATES;

EID: 34548484797     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9472-y     Document Type: Review

References (33)

1. Velayudham LS, Farrell GC (2003) Drug-induced cholestasis. Expert Opin Drug Saf 2:287-304
2. Benichou C (1990) Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol 11:272-276
3. Lazerow SK, Abdi MS, Lewis JH (2005) Drug-induced liver disease 2004. Curr Opin Gastroenterol 21:283-292
4. Lee WM, Senior JR (2005) Recognizing drug-induced liver injury: current problems, possible solutions. Toxicol Pathol 33:155- 164
5. Lazarou J, Pomeranz BH, Corey PN (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279:1200-1205
6. Hartleb M, Biernat L, Kochel A (2002) Drug-induced liver damage: a three-year study of patients from one gastroenterological department. Med Sci Monit 8:CR292-CR296
7. Lee WM (2003) Drug-induced hepatotoxicity (review). N Engl J Med 349:474-485
8. Bussieres JF, Habra M (1995) Application of International Consensus Meeting Criteria for classifying drug-induced liver disorders. Ann Pharmacother 29:875-878
9. Park BK, Kitteringham NR, Maggs JL, Pirmohamed M, Williams DP (2005) The role of metabolic activation in drug-induced hepatotoxicity. Annu Rev Pharmacol Toxicol 45:177-202
10. Gunawan B, Kaplowitz N (2004) Clinical perspectives on xenobiotic-induced hepatotoxicity. Drug Metab Rev 36:301-312
11. Galan MV, Potts JA, Silverman AL, Gordon SC (2005) Hepatitis in a United States tertiary referral center. J Clin Gastroenterol 39:64-67
12. Duh MS, Walker AM, Kronlund KH, Jr. (1999) Descriptive epidemiology of acute liver enzyme abnormalities in the general population of central Massachusetts. Pharmacoepidemiol Drug Saf. 8:275-283
13. Sgro C, Clinard F, Ouazir K, Chanay H, Allard C, Guilleminet C, Lenoir C, Lemoine A, Hillon P (2002) Incidence of drug-induced hepatic injuries: a French population-based study. Hepatology 36:451-455
14. Lewis JH (2002) The rational use of potentially hepatotoxic medications in patients with underlying liver disease. Expert Opin Drug Saf 1:159-172
15. Aithal PG, Day CP (1999) The natural history of histologically proved drug induced liver disease. Gut 44:731-735
16. Rashid M, Goldin R, Wright M (2004) Drugs and the liver. Hosp Med 65:456-461
17. Russo MW, Galanko JA, Shrestha R, Fried MW, Watkins P (2004) Liver transplantation for acute liver failure from drug induced liver injury in the United States. Liver Transpl 10:1018-1023
18. Li AP (2002) A review of the common properties of drugs with idiosyncratic hepatotoxicity and the "multiple determinant hypothesis" for the manifestation of idiosyncratic drug toxicity. Chem Biol Interact 142:7-23
19. Ju C (2005) Immunological mechanisms of drug-induced liver injury. Curr Opin Drug Discov Devel 8:38-43
20. Cullen JM (2005) Mechanistic classification of liver injury. Toxicol Pathol 33:6-8
21. Mackay IR (1999) Immunological perspectives on chronic hepatitis: virus infection, autoimmunity and xenobiotics. Hepatogastroenterology 46:3021-3033
22. Kaplowitz N (2002) Biochemical and cellular mechanisms of toxic liver injury. Semin Liver Dis 22:137-144
23. Holt MP, Ju C (2006) Mechanisms of drug-induced liver injury. AAPS J 8:E48-E54
24. Kaplowitz N (2004) Drug-induced liver injury. Clin Infect Dis 38(Suppl 2):S44-S48
25. Maddrey WC (2005) Drug-induced hepatotoxicity: 2005. J Clin Gastroenterol 39(4 Suppl 2):S83-S89
26. Aithal GP (2004) Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity. Expert Opin Drug Saf 3:519-523
27. Russo MW, Watkins PB (2004) Are patients with elevated liver tests at increased risk of drug-induced liver injury? Gastroenterology 126:1477-1480
28. Watkins PB (2005) Idiosyncratic liver injury: challenges and approaches. Toxicol Pathol 33:1-5
29. Hoofnagle JH, Carithers RL Jr, Shapiro C, Ascher N (1995) Fulminant hepatic failure: summary of a workshop. Hepatology 21:240-252
30. Amacher DE (2002) A toxicologist's guide to biomarkers of hepatic response. Hum Exp Toxicol 21:253-262
31. Hoofnagle JH (2004) Drug-induced liver injury network (DILIN). Hepatology 40:773
32. Ostapowicz G, Fontana RJ, Schiodt FV, Larson A, Davern TJ, Han SH, McCashland TM, Shakil AO, Hay JE, Hynan L, Crippin JS, Blei AT, Samuel G, Reisch J, Lee WM; U.S. Acute Liver Failure Study Group (2002) Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 137:947-954
33. Sniderman AD (2004) Is there value in liver function test and creatine phosphokinase monitoring with statin use? Am J Cardiol 94:30F-33F