Optimization and validation of an HPLC-UV method for determination of tranexamic acid in a dosage form and in human urine

Chromatographia

Volumn 66, Issue 5-6, 2007, Pages 311-317

  Hadad, Ghada M ^a   El Gindy, Alaa ^a   Mahmoud, Waleed M M ^a  

^a Suez Canal University   (Egypt)

Author keywords

Column liquid chromatography; Phenyl isothiocyanate; Tranexamic acid; Urinary excretion

Indexed keywords

ACETONITRILE; BUFFER; CARBON; HEPTAMINOL; PHENYL ISOTHIOCYANATE; POLICAPRAM; TRANEXAMIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; METHODOLOGY; NORMAL HUMAN; PH MEASUREMENT; PRIORITY JOURNAL; REACTION ANALYSIS; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; TEMPERATURE DEPENDENCE; URINALYSIS;

EID: 34548475800     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-007-0323-6     Document Type: Article

References (25)

1. Sweetman SC (2002) Martindale-the complete drug reference, 33rd edn. Pharmaceutical Press, London
2. Chang Q, Yin OQP, Chow MSS (2004) J Chromatogr B 805(2):275-280
3. Khuhawar MY, Rind FMA (2001) Chromatographia 53:709-711
4. Sato K, Tobita Y, Iwabuchi K, Tanaka S (1997) Anal Sci 13:471-474
5. Matsubayashi K, Kojima C, Tachizawa H (1988) J Chromatogr B 433:225-234
6. Diaz-Marot A, Monfort-Tort E, Comellas-Riera L, Gassiot-Matas M (1988) Afinidad 45:401-406
7. Uehara S, Hagiwara T, Takahashi M, Kamata K, Nakayama K, Akiyama K, Nishigaki S (1988) Iyakuhin-Kenkyu 19:98-102
8. Elworthy PM, Tsementzis SA, Westhead D, Hitchcock ER (1985) J Chromatogr B 343:109-117
9. Lacroix C, Levert P, Laine G, Goulle JP (1984) J Chromatogr B 309:183-186
10. Lin FM, Kou HS, Wu SM, Chen SH, Kwan AL, Wu HL (2005) Electrophoresis 26:621-626
11. Tampubolon HB, Sumarlik E, Yuwono M, Indrayanto G (2005) J Liq Chromatogr Related Technol 28:3243-3254
12. Ansari TM, Raza A, Rehman A (2005) Anal Sci 21:1133-1135
13. Rizk MS, Toubar SS, Sultan MA, Assaad SH (2003) Microchim Acta 143:281-285
14. Atmaca S (1989) Acta Pharm Turc 31:115-118
15. Takeuchi T, Kabasawa Y, Horikawa R, Tanimura T (1988) Analyst 113:1673-1675
16. Buyuktimkin N, Buyuktimkin S (1985) Acta Pharm Turc 27:78-81
17. Mohamed ME, Aboul-Enein HY (1984) Int J Environ Anal Chem 19:19-25
18. Wahbi AAM, Lotfi EA, Aboul-Enein HY (1984) Talanta 31:77-78
19. Iskender G, Atmaca S (1988) Pharmazie 43:290
20. Metrohm Application Note (2001) T-35:1
21. British Pharmacopoeia (2001) The Stationery Office, London
22. Zaitsu K, Kai M, Hamase K (1999) Reagent for UV-VIS detection. In: Toyo'oka T (ed) Modern derivatization methods for separation sciences. Wiley, New York, pp 68-70
23. Juan JBN, Carmen GC, Maria JVL, Virginia RR (2005) J Chromatogr A 1072:249-257
24. Draper NR, Smith H (1981) Fitting a straight line by least squares. In: Applied regression analysis. Wiley, New York, pp 22-40
25. European Agency for the Evaluation of Medical Products (1996) ICH topic Q2B, Note for guidance on validation of analytical procedures: methodology, GPMP/ICH/281/95