-
2
-
-
0028116510
-
Evidence for conformational dynamics and molecular aggregation in cytochrome P450 102 (BM-3)
-
Black, S. D., Martin, S. T. (1994). Evidence for conformational dynamics and molecular aggregation in cytochrome P450 102 (BM-3). Biochemistry 33:12056-12062.
-
(1994)
Biochemistry
, vol.33
, pp. 12056-12062
-
-
Black, S.D.1
Martin, S.T.2
-
3
-
-
0019888386
-
5 to the oxyferrous intermediate of liver microsomal cytochrome P-450 LM2
-
5 to the oxyferrous intermediate of liver microsomal cytochrome P-450 LM2. J. Biol. Chem. 256:9457-9465.
-
(1981)
J. Biol. Chem
, vol.256
, pp. 9457-9465
-
-
Bonfils, C.1
Balny, C.2
Maurel, P.3
-
4
-
-
0032476064
-
5 as a component of the reductive activation of porcine methionine synthase
-
5 as a component of the reductive activation of porcine methionine synthase. J. Biol. Chem. 273:26248-26255.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 26248-26255
-
-
Chen, Z.1
Banerjee, R.2
-
5
-
-
0030666084
-
Redox control of the catalytic cycle of flavocytochrome P450 BM3
-
Daff, S. N., Chapman, S. K., Turner, K. L., Holt, R. A., Govindaraj, S., Poulos, T. L., Munro, A. W. (1997). Redox control of the catalytic cycle of flavocytochrome P450 BM3. Biochemistry 36:13816-13823.
-
(1997)
Biochemistry
, vol.36
, pp. 13816-13823
-
-
Daff, S.N.1
Chapman, S.K.2
Turner, K.L.3
Holt, R.A.4
Govindaraj, S.5
Poulos, T.L.6
Munro, A.W.7
-
6
-
-
0016649146
-
Studies on the substrate specificity of the fatty acid 5-desaturase by the use of methyl branched isomers of eicose-8,11,14-trienoic acid and the metabolism of these acids in rat liver
-
Do, H. D., Sprecher, H. (1975). Studies on the substrate specificity of the fatty acid 5-desaturase by the use of methyl branched isomers of eicose-8,11,14-trienoic acid and the metabolism of these acids in rat liver. Arch. Biochem. Biophys. 171:597-603.
-
(1975)
Arch. Biochem. Biophys
, vol.171
, pp. 597-603
-
-
Do, H.D.1
Sprecher, H.2
-
9
-
-
0025922972
-
P450BM-3 and other inducible bacterial P450 cytochromes: Biochemistry and regulation
-
Fulco, A. J. (1991). P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation. Annu. Rev. Pharmacol. Toxicol. 31:177-203.
-
(1991)
Annu. Rev. Pharmacol. Toxicol
, vol.31
, pp. 177-203
-
-
Fulco, A.J.1
-
10
-
-
0025335197
-
5 oxidation-reduction equilibrium: Involvement of Asparagine-57, Serine-64, and heme propionate-7
-
5 oxidation-reduction equilibrium: Involvement of Asparagine-57, Serine-64, and heme propionate-7. Biochemistry 29:5500-5508.
-
(1990)
Biochemistry
, vol.29
, pp. 5500-5508
-
-
Funk, W.D.1
Lo, T.P.2
Mauk, M.R.3
Brayer, G.D.4
MacGillivray, R.T.A.5
Mauk, A.G.6
-
12
-
-
2542489445
-
Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set
-
Girvan, H. M., Marshall, K. R., Lawson, R. J., Leys, D., Joyce, M. G., Clarkson, J., Smith, W. E., Cheesman, M. R., Munro, A. W. (2004). Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set. J. Biol. Chem. 279:23274-23286.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 23274-23286
-
-
Girvan, H.M.1
Marshall, K.R.2
Lawson, R.J.3
Leys, D.4
Joyce, M.G.5
Clarkson, J.6
Smith, W.E.7
Cheesman, M.R.8
Munro, A.W.9
-
13
-
-
0022577938
-
5 on the formation of products in cytochrome P-450-catalyzed reactions
-
5 on the formation of products in cytochrome P-450-catalyzed reactions. Drug Metab. Dispos. 14:89-96.
-
(1986)
Drug Metab. Dispos
, vol.14
, pp. 89-96
-
-
Gorsky, L.D.1
Coon, M.J.2
-
14
-
-
0030960888
-
The domain architecture of cytochrome P450BM-3
-
Govindaraj, S., Poulos, T. L. (1997). The domain architecture of cytochrome P450BM-3. J. Biol. Chem. 272:7915-7921.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 7915-7921
-
-
Govindaraj, S.1
Poulos, T.L.2
-
16
-
-
2442552990
-
Expression, purification and characterization of Bacillus subtilis cytochromes CYP102A2 and CYP102A3: Flavocytochrome homologues of P450 BM3 from Bacillus megaterium
-
Gustafsson, M. C., Roitel, O., Marshall, K. R., Noble, M. A., Chapman, S. K., Pessegueiro, A., Fulco, A. J., Cheesman, M. R., von Wachenfeldt, C., Munro, A. W. (2004). Expression, purification and characterization of Bacillus subtilis cytochromes CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium. Biochemistry 43:5474-5487.
-
(2004)
Biochemistry
, vol.43
, pp. 5474-5487
-
-
Gustafsson, M.C.1
Roitel, O.2
Marshall, K.R.3
Noble, M.A.4
Chapman, S.K.5
Pessegueiro, A.6
Fulco, A.J.7
Cheesman, M.R.8
von Wachenfeldt, C.9
Munro, A.W.10
-
18
-
-
0035856545
-
Pivotal role of water in the mechanism of P450BM-3
-
Haines, D. C., Tomchick, D. R., Machius, M., Peterson, J. A. (2001). Pivotal role of water in the mechanism of P450BM-3. Biochemistry 40:13456-13465.
-
(2001)
Biochemistry
, vol.40
, pp. 13456-13465
-
-
Haines, D.C.1
Tomchick, D.R.2
Machius, M.3
Peterson, J.A.4
-
22
-
-
0017330428
-
Studies on three microsomal electron transfer systems. Specificity of electron flow pathways
-
Jansson, I., Schenkman, J. B. (1977). Studies on three microsomal electron transfer systems. Specificity of electron flow pathways. Arch Biochem. Biophys. 178:89-107.
-
(1977)
Arch Biochem. Biophys
, vol.178
, pp. 89-107
-
-
Jansson, I.1
Schenkman, J.B.2
-
23
-
-
0023160862
-
5 on the stoichiometry of the different oxidative reactions catalyzed by liver microsomal cytochrome P450
-
5 on the stoichiometry of the different oxidative reactions catalyzed by liver microsomal cytochrome P450. Drug Metab. Dispos. 15:344-348.
-
(1987)
Drug Metab. Dispos
, vol.15
, pp. 344-348
-
-
Jansson, I.1
Schenkman, J.B.2
-
26
-
-
0033544867
-
5
-
5. J. Biol. Chem. 274:35614-35620.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 35614-35620
-
-
Kostanjevečki, V.1
Leys, D.2
Van Driessche, G.3
Meyer, T.E.4
Cusanovich, M.A.5
Fischer, U.6
Guisez, Y.7
Van Beeumen, J.8
-
27
-
-
0021322969
-
Iron sulfur proteins of the purple sulfur bacterium Ectothiorhodospira shaposhnikovii
-
Kusche, W. H., Trüper, H. G. (1984). Iron sulfur proteins of the purple sulfur bacterium Ectothiorhodospira shaposhnikovii. Arch. Microbiol. 137:266-271.
-
(1984)
Arch. Microbiol
, vol.137
, pp. 266-271
-
-
Kusche, W.H.1
Trüper, H.G.2
-
30
-
-
0026452788
-
Domains of the catalytically self-sufficient cytochrome P450 BM-3. Genetic construction, overexpression, purification and spectroscopic characterization
-
Miles, J. S., Munro, A. W., Rospendowski, B. N., Smith, W. E., McKnight, J., Thomson, A. J. (1992). Domains of the catalytically self-sufficient cytochrome P450 BM-3. Genetic construction, overexpression, purification and spectroscopic characterization. Biochem. J. 288:503-509.
-
(1992)
Biochem. J
, vol.288
, pp. 503-509
-
-
Miles, J.S.1
Munro, A.W.2
Rospendowski, B.N.3
Smith, W.E.4
McKnight, J.5
Thomson, A.J.6
-
31
-
-
0030057886
-
Probing electron transfer in flavocytochrome P-450 BM3 and its component domains
-
Munro, A. W., Daff, S., Coggins, J. R., Lindsay, J. G., Chapman, S. K. (1996). Probing electron transfer in flavocytochrome P-450 BM3 and its component domains. Eur. J. Biochem. 239:403-409.
-
(1996)
Eur. J. Biochem
, vol.239
, pp. 403-409
-
-
Munro, A.W.1
Daff, S.2
Coggins, J.R.3
Lindsay, J.G.4
Chapman, S.K.5
-
32
-
-
33846356640
-
Cytochrome P450 - redox partner fusion enzymes
-
Munro, A. W., Girvan, H. M., McLean, K. J. (2007). Cytochrome P450 - redox partner fusion enzymes. Biochim. Biophys. Acta 1770:345-359.
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, pp. 345-359
-
-
Munro, A.W.1
Girvan, H.M.2
McLean, K.J.3
-
33
-
-
0036558027
-
P450 BM3: The very model of a modern flavocytochrome
-
Munro, A. W., Leys, D. G., McLean, K. J., Marshall, K. R., Ost, T. W., Daff, S., Miles, C. S., Chapman, S. K., Lysek, D. A., Moser, C. C., Page, C. C. Dutton, P. L. (2002). P450 BM3: the very model of a modern flavocytochrome. Trends Biochem. Sci. 27:250-257.
-
(2002)
Trends Biochem. Sci
, vol.27
, pp. 250-257
-
-
Munro, A.W.1
Leys, D.G.2
McLean, K.J.3
Marshall, K.R.4
Ost, T.W.5
Daff, S.6
Miles, C.S.7
Chapman, S.K.8
Lysek, D.A.9
Moser, C.C.10
Page, C.C.11
Dutton, P.L.12
-
34
-
-
0030009067
-
Bacterial cytochromes P-450
-
Munro, A. W., Lindsay, J. G. (1996). Bacterial cytochromes P-450. Mol. Microbiol. 20:1115-1125.
-
(1996)
Mol. Microbiol
, vol.20
, pp. 1115-1125
-
-
Munro, A.W.1
Lindsay, J.G.2
-
35
-
-
0029892430
-
Cytochrome P450foxy, a catalytically self-sufficient fatty acid hydroxylase of the fungus Fusarium oxysporum
-
Nakyama, N., Takamae, A., Shoun, H. (1996). Cytochrome P450foxy, a catalytically self-sufficient fatty acid hydroxylase of the fungus Fusarium oxysporum. J. Biochem. 119:435-440.
-
(1996)
J. Biochem
, vol.119
, pp. 435-440
-
-
Nakyama, N.1
Takamae, A.2
Shoun, H.3
-
36
-
-
26844498754
-
The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase
-
Neeli, R., Girvan, H. M., Lawrence, A., Warren, M. J., Leys, D., Scrutton, N. S., Munro, A. W. (2005). The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase. FEBS Lett. 579:5582-5588.
-
(2005)
FEBS Lett
, vol.579
, pp. 5582-5588
-
-
Neeli, R.1
Girvan, H.M.2
Lawrence, A.3
Warren, M.J.4
Leys, D.5
Scrutton, N.S.6
Munro, A.W.7
-
37
-
-
23844434591
-
Switching pyridine nucleotide specificity in P450 BM3: Mechanistic analysis of the W1046H and W1046A enzymes
-
Neeli, R., Roitel, O., Scrutton, N. S., Munro, A. W. (2005). Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes. J. Biol. Chem. 280:17634-17644.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 17634-17644
-
-
Neeli, R.1
Roitel, O.2
Scrutton, N.S.3
Munro, A.W.4
-
38
-
-
0026551035
-
5 or cytochrome P-450 in octyl glucoside micelles
-
5 or cytochrome P-450 in octyl glucoside micelles. Eur. J. Biochem. 204:1075-1082.
-
(1992)
Eur. J. Biochem
, vol.204
, pp. 1075-1082
-
-
Nisimoto, Y.1
Edmondson, D.E.2
-
39
-
-
0033561008
-
Roles of key active-site residues in flavocytochrome P450 BM3
-
Noble, M. A., Miles, C. S., Chapman, S. K., Lysek, D. A., MacKay, A. C., Reid., G. A., Hanzlik, R. P., Munro, A. W. (1999). Roles of key active-site residues in flavocytochrome P450 BM3. Biochem. J. 339:371-379.
-
(1999)
Biochem. J
, vol.339
, pp. 371-379
-
-
Noble, M.A.1
Miles, C.S.2
Chapman, S.K.3
Lysek, D.A.4
MacKay, A.C.5
Reid, G.A.6
Hanzlik, R.P.7
Munro, A.W.8
-
40
-
-
0019516164
-
Purification and partial characterization of lineloyl-CoA desaturase from rat liver microsomes
-
Okayasu, T., Nagao, M., Ishibashi, T., Imai, Y. (1981). Purification and partial characterization of lineloyl-CoA desaturase from rat liver microsomes. Arch. Biochem. Biophys. 206:21-28.
-
(1981)
Arch. Biochem. Biophys
, vol.206
, pp. 21-28
-
-
Okayasu, T.1
Nagao, M.2
Ishibashi, T.3
Imai, Y.4
-
41
-
-
78651165715
-
The carbon monoxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura, T., Sato, R. (1964). The carbon monoxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239:2370-2378.
-
(1964)
J. Biol. Chem
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
42
-
-
0035856564
-
Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3
-
Ost, T. W., Miles, C. S., Munro, A. W., Murdoch, J., Reid, G. A., Chapman, S. K. (2001). Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3. Biochemistry 40:13421-13429.
-
(2001)
Biochemistry
, vol.40
, pp. 13421-13429
-
-
Ost, T.W.1
Miles, C.S.2
Munro, A.W.3
Murdoch, J.4
Reid, G.A.5
Chapman, S.K.6
-
44
-
-
0037390012
-
Neutral thiol as a proximal ligand to ferrous heme iron: Implications for heme proteins that lose cysteine thiolate ligation on reduction
-
Perera, R., Sono, M., Sigman, J. A., Pfister, T. D., Lu, Y., Dawson, J. H. (2003). Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction. Proc. Natl. Acad. Sci. USA 100:3641-3646.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3641-3646
-
-
Perera, R.1
Sono, M.2
Sigman, J.A.3
Pfister, T.D.4
Lu, Y.5
Dawson, J.H.6
-
45
-
-
0032544220
-
Electron shuttle between membrane-bound cytochrome P450 3A4 and b5 rules uncoupling mechanisms
-
Perret, A., Pompon, D. (1998). Electron shuttle between membrane-bound cytochrome P450 3A4 and b5 rules uncoupling mechanisms. Biochemistry 37:11412-11424.
-
(1998)
Biochemistry
, vol.37
, pp. 11412-11424
-
-
Perret, A.1
Pompon, D.2
-
46
-
-
19944373388
-
Interaction of nitric oxide with cytochrome P450 BM3
-
Quaroni, L. G., Seward, H. E., McLean, K. J., Girvan, H. M., Ost, T. W., Noble, M. A., Kelly, S. M., Price, N. C., Cheesman, M. R., Smith, W. E., Munro, A. W. (2004). Interaction of nitric oxide with cytochrome P450 BM3. Biochemistry 43:16416-16431.
-
(2004)
Biochemistry
, vol.43
, pp. 16416-16431
-
-
Quaroni, L.G.1
Seward, H.E.2
McLean, K.J.3
Girvan, H.M.4
Ost, T.W.5
Noble, M.A.6
Kelly, S.M.7
Price, N.C.8
Cheesman, M.R.9
Smith, W.E.10
Munro, A.W.11
-
47
-
-
0001277625
-
Surface electrostatics, reduction potentials, and the internal dielectric constant of proteins
-
Rodgers, K. K., Sligar, S. G. (1991). Surface electrostatics, reduction potentials, and the internal dielectric constant of proteins. J. Am. Chem. Soc. 113:9419-9421.
-
(1991)
J. Am. Chem. Soc
, vol.113
, pp. 9419-9421
-
-
Rodgers, K.K.1
Sligar, S.G.2
-
48
-
-
0042819974
-
Electron transfer in flavocytochrome P450 BM3: Kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase
-
Roitel, O., Scrutton, N. S., Munro, A. W. (2003). Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase. Biochemistry 42:10809-10821.
-
(2003)
Biochemistry
, vol.42
, pp. 10809-10821
-
-
Roitel, O.1
Scrutton, N.S.2
Munro, A.W.3
-
50
-
-
0031106383
-
The function of recombinant cytochrome P450s in intact Escherichia coli cells: The 17-alpha-hydroxylation of progesterone and pregnenolone by P450c17
-
Shet, M. S., Fisher, C. W., Estabrook, R. W. (1997). The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17-alpha-hydroxylation of progesterone and pregnenolone by P450c17. Arch. Biochem. Biophys. 339:218-225.
-
(1997)
Arch. Biochem. Biophys
, vol.339
, pp. 218-225
-
-
Shet, M.S.1
Fisher, C.W.2
Estabrook, R.W.3
-
51
-
-
0027146638
-
Human cytochrome P450 3A4: Enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase
-
Shet, M. S., Fisher, C. W., Holmans, P. L., Estabrook, R. W. (1993). Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase. Proc. Natl. Acad. Sci. USA 90:11748-11752.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11748-11752
-
-
Shet, M.S.1
Fisher, C.W.2
Holmans, P.L.3
Estabrook, R.W.4
-
53
-
-
0024468304
-
5-cytochrome P-450cam association: A proposed molecular model for a cytochrome P-450cam electron-transfer complex
-
5-cytochrome P-450cam association: A proposed molecular model for a cytochrome P-450cam electron-transfer complex. Biochemistry 28:8201-8205.
-
(1989)
Biochemistry
, vol.28
, pp. 8201-8205
-
-
Stayton, P.S.1
Poulos, T.L.2
Sligar, S.G.3
-
54
-
-
0010426032
-
Purification and properties of rat liver microsomal stearyl coenzyme A desaturase
-
Strittmatter, P., Spatz, L., Corcoran, D., Rogers, M. J., Setlow, B., Redline, R. (1974). Purification and properties of rat liver microsomal stearyl coenzyme A desaturase. Proc. Natl. Acad. Sci. USA 71:4565-4569.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 4565-4569
-
-
Strittmatter, P.1
Spatz, L.2
Corcoran, D.3
Rogers, M.J.4
Setlow, B.5
Redline, R.6
-
57
-
-
0026612528
-
5 in yeast and characterization of mutants of the membrane-anchoring domain
-
5 in yeast and characterization of mutants of the membrane-anchoring domain. J. Biol. Chem. 267:12583-12591.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 12583-12591
-
-
Vergeres, G.1
Waskell, L.2
-
58
-
-
0024507717
-
Induction of microsomal NADPH-cytochrome P-450 reductase and cytochrome P-450IVA1 (P-450LA omega) by dehydroepiandrosterone in rats: A possible peroxisomal proliferator
-
Wu, H. Q., Masset-Brown, J., Tweedie, D. J., Milewich, L., Frenkel, R. A., Martin-Wixtrom, C., Estabrook, R. W., Prough, R. A. (1998). Induction of microsomal NADPH-cytochrome P-450 reductase and cytochrome P-450IVA1 (P-450LA omega) by dehydroepiandrosterone in rats: a possible peroxisomal proliferator. Cancer Res. 49:2337-2343.
-
(1998)
Cancer Res
, vol.49
, pp. 2337-2343
-
-
Wu, H.Q.1
Masset-Brown, J.2
Tweedie, D.J.3
Milewich, L.4
Frenkel, R.A.5
Martin-Wixtrom, C.6
Estabrook, R.W.7
Prough, R.A.8
|