Nephrogenesis and the renal renin-angiotensin system in fetal sheep: Effects of intrauterine growth restriction during late gestation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 293, Issue 3, 2007, Pages

  Zohdi, Vladislava ^a   Moritz, Karen M ^a   Bubb, Kristen J ^a   Cock, Megan L ^a   Wreford, Nigel ^a   Harding, Richard ^a   Black, M Jane ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Kidney; Macula densa; Nephron endowment; Stereology

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSINOGEN;

ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GESTATION PERIOD; KIDNEY CORTEX; KIDNEY DEVELOPMENT; KIDNEY MASS; KIDNEY PERFUSION; MACULA DENSA; MALE; NEPHRON; NONHUMAN; PRENATAL GROWTH; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SHEEP; THIRD TRIMESTER PREGNANCY;

ANGIOTENSIN II; ANGIOTENSINOGEN; ANIMALS; BODY WEIGHT; ERYTHROCYTE INDICES; FEMALE; FETAL GROWTH RETARDATION; FETAL WEIGHT; FETUS; GENE EXPRESSION; GESTATIONAL AGE; KIDNEY; NEPHRONS; ORGAN SIZE; PREGNANCY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RENIN; RENIN-ANGIOTENSIN SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SHEEP;

EID: 34548445397     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00119.2007     Document Type: Article

References (45)

1. Albertsson-Wikland K, Wennergren G, Wennergren M, Vilbergsson G, Rosberg S. Longitudinal follow-up of growth in children born small for gestational age. Acta Paediatr 82: 438-443, 1993.
2. Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life and mortality from cardiovascular disease. BMJ 298: 564-567, 1989.
3. Bassan H, Trejo LL, Kariv N, Bassan M, Berger E, Fattal A, Gozes I, Harel S. Experimental intrauterine growth retardation alters renal development. Pediatr Nephrol 15: 192-195, 2000.
4. Bell PD, Lapointe JY. Characteristics of membrane transport processes of macula densa cells. Clin Exp Pharmacol Physiol 24: 541-547, 1997.
5. Bertram JF. Analyzing renal glomeruli with the new stereology. Int Rev Cytol 161: 111-172, 1995.
6. Black MJ, Briscoe TA, Constantinou M, Kett MM, Bertram JF. Is there an association between level of adult blood pressure and nephron number or renal filtration surface area? Kidney Int 65: 582-588, 2004.
7. Bubb KJ, Cock ML, Black MJ, Dodic M, Boon WM, Parkington HC, Harding R, Tare M. Intrauterine growth restriction delays cardiomyocyte maturation and alters coronary artery function in the fetal sheep. J Physiol 578: 871-881, 2007.
8. Butkus A, Albiston A, Alcorn D, Giles M, McCausland J, Moritz K, Zhuo J, Wintour EM. Ontogeny of angiotensin II receptors, types 1 and 2, in ovine mesonephros and metanephros. Kidney Int 52: 628-636, 1997.
9. Cock ML, Harding R. Renal and amniotic fluid responses to umbilicoplacental embolization for 20 days in fetal sheep. Am J Physiol Regul Integr Comp Physiol 273: R1094-R1102, 1997.
10. Gimonet V, Bussieres L, Medjebeur AA, Gasser B, Lelongt B, Laborde K. Nephrogenesis and angiotensin II receptor subtypes gene expression in the fetal lamb. Am J Physiol Renal Physiol 274: F1062-F1069, 1998.
11. Gomez RA. Role of angiotensin in renal vascular development. Kidney Int Suppl 67: S12-S16, 1998.
12. Gubhaju L, Black MJ. The baboon is a good model for studies of human kidney development. Pediatr Res 58: 505-509, 2005.
13. Gundersen HJ, Bendsten TF, Korbo L, Marcussen N, Moller A, Nielsen K. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96: 379-394, 1988.
14. Guron G, Friberg P. An intact renin-angiotensin system is a prerequisite for normal development. J Hypertens 18: 123-137, 2000.
15. Hinchliffe SA, Lynch MR, Sargent PH, Howard CV, VanVelzen D. The effect of intrauterine growth retardation on the development of renal nephrons. Br J Obstet Gynaecol 99: 296-301, 1992.
16. Hostetter TH. Hyperfiltration and glomerulosclerosis. Semin Nephrol 23: 194-199, 2003.
17. Howard CV, Reed MG. Unbiased Stereology Three-Dimensional Measurement in Microscopy. New York: Bios Scientific, 1998.
18. Hoy WE, Rees M, Kile E, Mathews JD, Wang Z. A new dimension to the Barker hypothesis: low birthweight and susceptibility to renal disease. Kidney Int 56: 1072-1077, 1999.
19. Hoy WE, Hughson MD, Singh GR, Douglas-Denton R, Bertram JF. Reduced nephron number and glomerulomegaly in Australian Aborigines: a group at high risk for renal disease and hypertension. Kidney Int 70: 104-110, 2006.
20. Hughson M, Farris AB 3rd, Douglas-Denton R, Hoy WE, Bertram JF. Glomerular number and size in autopsy kidneys: the relationship to birth weight. Kidney Int 63: 2113-2122, 2003.
21. Hughson MD, Douglas-Denton R, Bertram JF, Hoy WE. Hypertension, glomerular number and birth weight in African Americans and white subjects in the southeastern United States. Kidney Int 69: 671-678, 2006.
22. Langley-Evans SC, Welham SJ, Jackson AA. Fetal exposure to a maternal low protein diet impairs nephrogenesis and promotes hypertension in the rat. Life Sci 64: 965-974, 1999.
23. Louey S, Cock ML, Stevenson KM, Harding R. Placental insufficiency and fetal growth restriction lead to postnatal hypotension and altered postnatal growth in sheep. Pediatr Res 48: 808-814, 2000.
24. Luyckx VA, Brenner BM. Low birth weight, nephron number and kidney disease. Kidney Int Suppl 97: S68-S77, 2005.
25. Merlet-Benichou C, Gilbert T, Muffat-Joly M, Lelievre-Pegorier M, Leroy B. Intrauterine growth retardation leads to a permanent nephron deficit in the rat. Pediatr Nephrol 8: 175-180, 1994.
26. Mitchell EKL, Louey S, Cock ML, Harding R, Black MJ. Nephron endowment and filtration surface area in the kidney after growth restriction of fetal sheep. Pediatr Res 55: 769-773, 2004.
27. Moritz KM, Wintour EM. Functional development of the meso- and metanephros. Pediatr Nephrol 13: 171-178, 1999.
28. Moritz KM, Koukoulas I, Albiston A, Wintour EM. Angiotensin II infusion to the midgestation ovine fetus: effects on the fetal kidney. Am J Physiol Regul Integr Comp Physiol 279: R1290-R1297, 2000.
29. Nagata M, Scharer K, Kriz W. Glomerular damage after uninephrectomy in young rats. I. Hypertrophy and distortion of capillary architecture. Kidney Int 42: 136-147, 1992.
30. Nenov VD, Taal MW, Sakharova OV, Brenner BM. Multi-hit nature of chronic renal disease. Curr Opin Nephrol Hypertens 9: 85-97, 2000.
31. Nyengaard JR. Number and dimensions of rat glomerular capillaries in normal development and after nephrectomy. Kidney Int 43: 1049-1057, 1993.
32. Persson AE, Ollerstam A, Liu R, Brown R. Mechanisms for macula densa cells release of renin. Acta Physiol Scand 181: 471-475, 2003.
33. Plank C, Ostreicher I, Hartner A, Markek I, Struwe FG, Amann K, Hilgers KF, Rascher W, Dotsch J. Intrauterine growth retardation aggravates the course of acute mesangioproliferative glomerulonephritis in the rat. Kidney Int 70: 1974-1982, 2006.
34. Reed GF, Lynn F, Meade BD. Use of coefficient of variation in assessing variability of quantitative assays. Clin Diagn Lab Immunol 9: 1235-1239, 2002.
35. Rich-Edwards J, Stampfer M, Manson J, Colditz G, Willett W, Hennekens C. Birth weight and risk of cardiovascular disease in a cohort of women followed up since 1976. BMJ 315: 396-400, 1997.
36. Robillard JE, Page WV, Mathews MS, Schutte BC, Nuyt AM, Segar JL. Differential gene expression and regulation of renal angiotensin II receptor subtypes (AT1 and AT2) during fetal life in sheep. Pediatr Res 38: 896-904, 1995.
37. Rossing P, Tarnow L, Nielsen FS, Hansen BV, Brenner BM, Parving HH. Low birth weight. A risk factor for development of diabetic nephropathy? Diabetes 44: 1405-1407, 1996.
38. Ruster M, Sommer M, Stein G, Bauer K, Walter B, Wolf G, Bauer R. Renal angiotensin receptor type 1 and 2 upregulation in intrauterine growth restriction of newborn piglets. Cells Tissues Organs 182: 106-114, 2006.
39. Saxen L. Organogenesis of the Kidney. Cambridge, UK: Cambridge Univ. Press, 1987, p. 1-34.
40. Schutz S, LeMoullec JM, Corvol P, Gasc JM. Early expression of all the components of the renin-angiotensin-system in human development. Am J Pathol 149: 2067-2079, 1996.
41. Vehaskari VM, Stewart T, Lafont D, Soyez C, Seth D, Manning J. Kidney angiotensin and angiotensin receptor expression in prenatally programmed hypertension. Am J Physiol Renal Physiol 287: F262-F267, 2004.
42. Welham SJM, Wade A, Woolf AS. Protein restriction in pregnancy is associated with increased apoptosis of mesenchymal cells at the start of rat metanephrogenesis. Kidney Int 61: 1231-1242, 2002.
43. Woods LL, Ingelfinger JR, Nyengaard JR, Rasch R. Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediatr Res 49: 460-467, 2001.
44. Zhang DY, Lumbers ER, Simonetta G, Wu JJ, Owens JA, Robinson JS, McMillen IC. Effects of placental insufficiency on the ovine fetal renin-angiotensin system. Exp Physiol 85: 79-84, 2000.
45. Zimanyi MA, Denton KM, Forbes JM, Thallas-Bonke V, Thomas MC, Poon F, Black MJ. A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products. Diabetologia 49: 801-810, 2006.