Polymeric drug based on sulfanilamide: Synthesis, antimicrobial and drug releasing studies

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 9, 2007, Pages 1207-1213

  Umamaheswara Reddy, C ^a   Arun, A ^b,c   Amalraj, A ^a   Reddy, B S R ^b  

^a SRI RAMACHANDRA UNIVERSITY   (India)

^b CENTRAL LEATHER RESEARCH INSTITUTE   (India)

^c GOVERNMENT ARTS COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTANONE; 2 HYDROXYETHYLACETATE; ACETIC ACID DERIVATIVE; ACRYLIC ACID; BENZOYL PEROXIDE; FREE RADICAL; MONOMER; N [(4 AMINO SULFONYL)PHENYL]ACRYLAMIDE; POLYMER; SOLVENT; SULFANILAMIDE; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG ABSORPTION; DRUG MONITORING; DRUG RELEASE; DRUG SYNTHESIS; ESCHERICHIA COLI; FILM; GRAM POSITIVE BACTERIUM; INFRARED SPECTROSCOPY; KLEBSIELLA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH; POLYMERIZATION; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHI; SPECTROPHOTOMETER; STAPHYLOCOCCUS AUREUS; TEMPERATURE; ULTRAVIOLET SPECTROPHOTOMETRY;

ACRYLATES; ANTI-BACTERIAL AGENTS; BACTERIA; BENZOYL PEROXIDE; BUTANONES; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; GRAM-POSITIVE BACTERIA; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; POLYMERS; SOLVENTS; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFANILAMIDES; TEMPERATURE;

EID: 34548443459     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.9.0004     Document Type: Article

References (34)

1. Arshady, R. (1993) Polymer synthesis via activated esters. Adv. Polym. Sci. 111: 1-41
2. Arun, A., Reddy, B. S. R. (2005) In vitro drug release studies from the polymeric hydrogels based on HEA and HPMA using 4-{(E)-[(3Z)-3-(4-(acryloyloxy) benzylidene)-2-hexylidene]methyl}pheyl acrylate as a crosslinker. Biomaterials 26: 1185-1193
3. Arun, A., Reddy, B. S. R., Rajkumar, M. (2003) Polymeric drug for antimicrobial activity studies: synthesis and characterization. J. Bio Active Compatible Polymers 18: 219-228
4. Attwood, D., Florence, A. T., Gillian, J. M. N. (1974) Micellar properties of drugs. Properties of micellar aggregates of phenothiazines and their aqueous solutions. J. Pharm. Sci. 63: 988-993
5. Bissonnette, L., Roy, P. H. (1992) Characterization of InO pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of gram-negative bacteria. J. Bacteriol. 174: 1248-1257
6. Bolard, J., Legrand, P., Heitz, F., Cybulska, B. (1991) One sided action of amphotericin B on cholesterol-containing membrane is determined by its self-association in the medium. Biochemistry 30: 5707-5715
7. Boudreaux, C. J., Bunyard, W. C., McCormick, C. L. (1996) Controlled activity polymers. VIII. Copolymers of acrylic acid and isomeric N-alkylacrylamide with pendent β3-naphthol esters moieties: Synthesis and characterization. J. Control. Release 40: 223-233
8. Davaran, S., Entezami, A. A. (1997) Acrylic type polymers containing ibuprofen and indomethacin with difunctional spacer group: synthesis and hydrolysis. J. Control. Release 47: 41-49
9. Davaran, S., Entezami, A. A. (1998) Hydrophilic copolymers prepared from acrylic type derivatives of ibuprofen containing hydrolysable thioester bond. Eur. Polym. J. 34: 187-192
10. Davaran, S., Hanace, J., Khosravi, A. (1999) Release of 5-amino salicylic acid from acrylic type polymeric prodrugs designed for colon-specific drug delivery. J. Control. Release 58: 279-287
11. Elvira, C., Gallardo, A., Lacroix, N., Schacht, E., Sanroman, J. (2001) Incorporation of acrylic salicylic derivatives to hydrophilic copolymer systems with biomedical applications. J. Mater. Sci. Mater. Med. 12: 535-542
12. Foolandi, M. M. (1979) PhD dissertation. University of Southern Mississippi. Hattiesburg
13. Ford, C., Hamel, J., Stapert, D., Moerman, J., Hutchinson, D., Barbachyn, M., Zurenko, G., 1999 Oxazolidinones: a new class of antimicrobials. Infect. Med. 16: 435-445
14. Gallardo, A., Sanroman, J. (1993) Synthesis and characterization of new poly (methacrylamide) bearing side groups of biomedical interest. Polymer 34: 394-400
15. Gallardo, A., Pavejo, C., Sanroman, J. (2001) NSAIDs bound to methacrylic carriers. Micro structural characterization and in vitro release analysis. J. Control. Release 71: 127-140
16. Harris, F. W. (1984) Controlled release from polymers containing pendent bio active substituents. In: Langer, R. S., Wise, D. L. (eds) Medical applications of controlled release. CRC press, Boca Raton, FL
17. Ibrahim Erol (2004) Synthesis, characterization and biological activity of [2-oxo-2-(4-acetyl)phenyl amino] ethylene methacrylate and its derivatives. J. Polym. Sci. Part A: Polym. Chem. 42: 3157-3169
18. Liso, P. A., Rebulta, M., San Roman, J., Gallardo, A., Villar, A. M. (1995) Antinociceptive and antipyretic properties of a new conjugated ibuprofen-methacrylic polymeric controlled delivery system. J. Control. Release 33: 429-436
19. McCormick, C. L. (1985) Controlled activity polymers with pendent metribuzin: effect of structure on hydrolytic release. Ann. NY Acad. Sci. 446: 76-92
20. Mikes, F., Strop, P., Seyebk, O., Roda, J., Kalal, J. (1974) Co-polymerization of 2-hydroxyethyl methacrylate with vinyl pyridine and with N-substituted methacrylamides. Eur. Polym. J. 10: 1029-1032
21. Mouritsen, O. G., Jorgensen, K. (1994) Dynamical order and disorder in lipid bilayers. Chem. Phys. Lipids 73: 3-25
22. Nikaido, H. (2000) Crossing the envelope: how cephalosporins reach their targets. Clin. Microbiol. Infect. 6: 22-26
23. Nikaido, H. (2001) Preventing drug access to targets: cell surface permeability barriers and active efflux in bacteria. Semin. Cell Dev. Biol. 12: 215-223
24. Normark, B. H., Normark, S. (2002) Evolution and spread of antibiotic resistance. J. Int. Med. 252: 91-106
25. th Edn, McGraw-Hill, OH, pp 42-68
26. Roman, J. S., Madruga, E. L. (1989) Polymers with pharmacologically activities: synthesis and free radical polymerization of p- methacryloyloxyacetanilide. Polymer 30: 949-954
27. Roman, J. S., Levenfeld, B. (1990) Polymers with pharmacological activity. 3. Stereochemical configuration of acrylic polymers bearing paracetamol and phenacetin side groups. Macromolecules 23:423-427
28. th international symposium on controlled release of bioactive materials. 3.18-3.28. University of Akron Press
29. Seeman, P. (1972) The membrane actions of anesthetics and tranquilizers. Pharmacol. Rev. 24: 583-655
30. Sharkawi, T., Leyni-Barbaz, D., Chikh, N., McMullen, J. N. (2005) Evaluation of the in vitro drug release from resorbable biocompatible coatings for vascular stents. J. Bio Active Compatible Polymers 20: 153-168
31. Skold, O. (2000) Sulfonamide resistance: mechanism and trends. Drug Resistance Updates 3: 155-160
32. Skold, O. (2001) Resistance to trimethoprim and sulfonamides. Vet. Res. 32: 261-273
33. Thamizharasi, S., Vasantha, J., Reddy, B. S. R. (2002) Synthesis, characterization and pharmacologically active sulphamethoxazole polymers. Euro. Polym. J. 38: 551-559
34. Vogl, O., Tirrell, D. (1979) Functional polymers with biologically active group. J. Macromol. Sci. Chem. A13: 415-439