Vascular Endothelial Growth Factor Immunostaining Correlates with Postoperative Relapse and Survival in Non-Small Cell Lung Cancer

Archives of Medical Research

Volumn 38, Issue 7, 2007, Pages 764-768

  Yilmaz, Aydin ^a   Ernam, Dilek ^a   Unsal, Ebru ^a   Demirag, Funda ^b   Atikcan, Şükran ^a   Taştepe, Irfan ^a  

^a Research Hospital   (Turkey)

^b Zekai Tahir Burak Women's Health Education   (Turkey)

Author keywords

NSCLC; Postoperative relapse; Prognosis; Survival; VEGF

Indexed keywords

ANTINEOPLASTIC AGENT; VASCULOTROPIN;

ADULT; AGE; AGED; ARTICLE; CANCER PATIENT; CANCER RELAPSE; CANCER STAGING; CANCER SURVIVAL; CANCER TISSUE; CLINICAL ARTICLE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG NON SMALL CELL CANCER; MALE; POSTOPERATIVE PERIOD; PROGNOSIS;

ADULT; AGED; CARCINOMA, NON-SMALL-CELL LUNG; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; SURVIVAL RATE; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34548434337     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2007.04.005     Document Type: Article

References (24)

1. Bremnes R.M., Camps C., and Sirera R. Angiogenesis in non-small cell lung cancer: the prognostic impact of neoangiogenesis and the cytokines VEGF and bFGF in tumours and blood. Lung Cancer 51 (2006) 143-158
2. Ferrara N. Vascular endothelial growth factor. Eur J Cancer 32 (1996) 2413-2422
3. Yuan A., Yu C.J., Kuo S.H., Chen W.J., Lin F.Y., Luh K.T., et al. Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer. J Clin Oncol 19 (2001) 432-441
4. Takahashi Y., Kitadai Y., Bucana C.D., Cleary K.R., and Ellis L.M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 55 (1995) 3964-3968
5. Brown L.F., Berse B., Jackman R.W., Tognazzi K., Guidi A.J., Dvorak H.F., et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 26 (1995) 86-91
6. Plate K.H., Breier G., Millauer B., Ullrich A., and Risau W. Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res 53 (1993) 5822-5827
7. Suzuki K., Hayashi N., Miyamoto Y., Yamamoto M., Ohkawa K., Ito Y., et al. Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. Cancer Res 56 (1996) 3004-3009
8. Demirag F., Unsal E., Yilmaz A., and Caglar A. Prognostic significance of vascular endothelial growth factor, tumor necrosis and mitotic activity index in malignant pleural mesothelioma. Chest 128 (2005) 3382-3387
9. Mountain C.F. Revisions in the International System for Staging Lung Cancer. Chest 111 (1997) 1710-1717
10. Scagliotti G. Consensus development conference on the medical treatment of non-small cell lung cancer: treatment of the early stages. Lung Cancer 38 (2002) S23-S29
11. Franklin W.A. Diagnosis of lung cancer: pathology of neoplasia and preinvasive neoplasia. Chest 117 Suppl (2000) 80-89 (Travis WD, Colby TV, Corrin B. Histological typing of tumors of lung and pleura. In Sobin LH, ed. WHO International Classification of Tumours, 3rd ed. Berlin: Springer; 1999)
12. Ito H., Oshita F., Kameda Y., Suzuki R., Ikehara M., Arai H., et al. Expression of vascular endothelial growth factor and basic fibroblast growth factor in small adenocarcinomas. Oncol Rep 9 (2002) 119-123
13. O'Byrne K.J., Koukourakis M.I., Giatromanolaki A., Cox G., Turley H., Steward W.P., et al. Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. Br J Cancer 82 (2000) 1427-1432
14. Shijubo N., Uede T., Kon S., Maeda M., Segawa T., Imada A., et al. Vascular endothelial growth factor and osteopontin in stage I lung adenocarcinoma. Am J Respir Crit Care Med 160 (1999) 1269-1273
15. Macchiarini P., Fontanini G., Hardin M.J., Squartini F., and Angeletti G.A. Relation of neovascularization to metastasis of non small cell lung cancer. Lancet 340 (1992) 145-146
16. Kim K.J., Li B., Winer J., Armanini M., Gillett N., Phillips H.S., et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362 (1993) 841-844
17. Kondo S., Asano M., and Suzuki H. Significance of vascular endothelial growth factor/vascular permeability factor for solid tumor growth, and its inhibition by the antibody. Biochem Biophys Res Commun 194 (1993) 1234-1241
18. Yano T., Tanikawa S., Fujie T., Masutani M., and Horie T. Vascular endothelial growth factor expression and neovascularisation in non-small cell lung cancer. Eur J Cancer 36 (2000) 601-609
19. Matsuyama K., Chiba Y., Sasaki M., Tanaka H., Muraoka R., Tanigawa N., et al. Tumor angiogenesis as a prognostic marker in operable non-small cell lung cancer. Ann Thorac Surg 65 (1998) 1405-1409
20. Han H., Silverman J.F., Santucci T.S., Macherey R.S., D'Amato T.A., Tung M.Y., et al. Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis. Ann Surg Oncol 8 (2001) 72-79
21. Seto T., Higashiyama M., Funai H., Imamura F., Uematsu K., Seki N., et al. Prognostic value of expression of vascular endothelial growth factor and its flt-1 and KDR receptors in stage I non-small-cell lung cancer. Lung Cancer 53 (2006) 91-96
22. Niki T., Iba S., Tokunou M., Yamada T., Matsuno Y., and Hirohashi S. Expression of vascular endothelial growth factors A,B,C and D and their relationships to lymph node status in lung adenocarcinoma. Clin Cancer Res 6 (2000) 2431-2439
23. Nakashima T., Huang C.L., Liu D., Kameyama K., Masuya D., Ueno M., et al. Expression of vascular endothelial growth factor-A and vascular endothelial growth factor-C as prognostic factors for non small cell lung cancer. Med Sci Monit 10 (2004) 157-165
24. Sandler A.B. Targeting angiogenesis in lung cancer. Semin Oncol 32 (2005) S16-S22