Hypoxia in Head and Neck Cancer: Studies With Hypoxic Positron Emission Tomography Imaging and Hypoxic Cytotoxins

International Journal of Radiation Oncology Biology Physics

Volumn 69, Issue 2 SUPPL., 2007, Pages

  Rischin, Danny ^a,b,c   Fisher, Richard ^a,b,c   Peters, Lester ^a,b,c   Corry, June ^a,b,c   Hicks, Rodney ^a,c  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Trans Tasman Radiation Oncology Group   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; 2 NITROIMIDAZOLE DERIVATIVE; AZOMYCIN ARABINOSIDE F 18; CISPLATIN; FLUORINE 18; TIRAPAZAMINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RISK; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CORRELATION ANALYSIS; DIAGNOSTIC IMAGING; HEAD AND NECK CARCINOMA; HUMAN; HYPOXIA; INTERMETHOD COMPARISON; LYMPH NODE; METASTASIS; MONOTHERAPY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; TREATMENT FAILURE;

CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CISPLATIN; CLINICAL TRIALS AS TOPIC; HEAD AND NECK NEOPLASMS; HUMANS; POSITRON-EMISSION TOMOGRAPHY; PROGNOSIS; RADIATION-SENSITIZING AGENTS; TRIAZINES;

EID: 34548431352     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.05.043     Document Type: Article

References (7)

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2. Brown J.M. SR 4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours. Br J Cancer 67 (1993) 1163-1170
3. Lee D.J., Trotti A., Spencer S., et al. Concurrent tirapazamine and radiotherapy for advanced head and neck carcinomas: A phase II study. Int J Radiat Oncol Biol Phys 42 (1998) 811-815
4. Rischin D., Peters L., Hicks R.J., et al. Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer. J Clin Oncol 19 (2001) 535-542
5. Rischin D., Peters L., Fisher R., et al. Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: A randomized phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02). J Clin Oncol 23 (2005) 79-87
6. Koh W.J., Bergman K.S., Rasey J.S., et al. Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography. Int J Radiat Oncol Biol Phys 33 (1995) 391-398
7. Rischin D., Hicks R.J., Fisher R., et al. Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group Study 98.02. J Clin Oncol 24 (2006) 2098-2104