Herpes virus inhibitory substances from Hypericum connatum Lam., a plant used in southern Brazil to treat oral lesions

Journal of Ethnopharmacology

Volumn 113, Issue 3, 2007, Pages 517-520

  Fritz, Daniela ^a   Venturi, Caroline Rita ^a   Cargnin, Simone ^a   Schripsema, Jan ^b   Roehe, Paulo Michel ^c   Montanha, Jarbas Alves ^a   von Poser, Gilsane Lino ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

^c Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

Author keywords

Antiherpetic activity; Guttiferae; Herpes simplex viruses; Hypericum connatum; Luteoforol; Quercetin derivatives

Indexed keywords

AMENTOFLAVONE; DICHLOROMETHANE; FLAVONOID; GUAIJAVERINE; HEXANE; HYPERBRASILOL B; HYPERICUM CONNATUM EXTRACT; HYPERIN; LUTEOFOROL; METHANOL; PHLOROGLUCINOL DERIVATIVE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BRAZIL; CHEMICAL ANALYSIS; CONTROLLED STUDY; HERPES SIMPLEX VIRUS; MOUTH LESION; NONHUMAN; VIRUS STRAIN;

ANIMALS; ANTIVIRAL AGENTS; BRAZIL; CERCOPITHECUS AETHIOPS; FLAVONOIDS; HYPERICUM; MEDICINE, TRADITIONAL; MOUTH DISEASES; PHLOROGLUCINOL; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; SIMPLEXVIRUS; VERO CELLS;

CLUSIACEAE; HERPESVIRIDAE; HUMAN HERPESVIRUS 1; HYPERICUM CONNATUM; SIMPLEXVIRUS;

EID: 34548430430     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.07.013     Document Type: Article

References (19)

1. Amaral A.C.F., Kuster R.M., Gonçalves J.L.S., and Wigg M.D. Antiviral investigation on the flavonoids of Chamaesyce thymifolia. Fitoterapia 70 (1999) 293-295
2. Arisawa M., Fujita A., Hayashi T., Hayashi K., Ochiai H., and Morit N. Cytotoxic and antiherpetic activity of phloroglucinol derivatives from Mallotus japonicus (Euphorbiaceae). Chemical Pharmaceutical Bulletin 38 (1990) 1624-1626
3. Correa M.P. Dicionário das Plantas Úteis do Brasil e das Exóticas Cultivadas (1984), Instituto Brasileiro de Desenvolvimento Florestal, Rio de Janeiro
4. Fritz, D., 2006. Análise química e avaliação da atividade antiviral de Hypericum connatum Lam. MS Thesis, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, p. 123.
5. Hook E.W., Cannon R.O., Nahmias A.J., Lee F.F., Campbell Jr. C.H., Glasser D., and Quinn T.C. Herpes simplex virus infection as a risk factor for human immunodeficiency virus infection in heterosexuals. The Journal of Infectious Diseases 165 (1992) 251-255
6. Lin Y.M., Flavin M.T., Schure R., Chen F.C., Sidwell R., Barnard D.L., Huffman J.H., and Kern E.R. Antiviral activities of biflavonoids. Planta Medica 65 (1999) 120-125
7. Mentz L.A., Lutzemberger L.C., and Schenkel E.P. Da flora medicinal do Rio Grande do Sul: notas sobre a obra de D'Avila (1910). Cadernos de Farmácia 15 (1997) 25-47
8. Montanha J.A., Moellerke P., Bordignon S.A.L.J., Schenkel E.P., and Roehe P.M. Antiviral activity of Brazilian plant extracts. Acta Farmacéutica Bonaerense 23 (2004) 183-186
9. Nör C., Albring D., Ferraz A.B.F., Schripsema J., Pires V., Sonnet P., Guillaume D., and Von Poser G.L. Phloroglucinol derivatives from four Hypericum species belonging to the Trigynobrathys section. Biochemical Systematics and Ecology 32 (2004) 517-519
10. In: Payment P., and Trudel M. (Eds). Manuel de techniques virologiques (1989), Presses de l'Université du Québec, Québec
11. Rocha L., Marston A., Potterat O., Kaplan M.A.C., and Hostettmann K. More phloroglucinols from Hypericum brasiliense. Phytochemistry 42 (1996) 185-188
12. Schmitt A.C., Ravazzolo A.P., and von Poser G.L. Investigation of some Hypericum species native to southern of Brazil for antiviral activity. Journal of Ethnopharmacology 77 (2001) 239-245
13. Serkedjieva J., and Ivancheva S. Antiherpes virus activity of extracts from the medicinal plant Geranium sanguineum L. Journal of Ethnopharmacology 64 (1999) 59-68
14. Sidwell R.W., and Huffman J.H. Use of disposable micro tissue culture plates for antiviral and interferon induction studies. Applied Microbiology 22 (1971) 797-801
15. Spinelli F., Speakman J.-B., Rademacher W., Halbwirth H., Stich K., and Costa G. Luteoforol, a flavan 4-ol, is induced in pome fruits by prohexadione-calcium and shows phytoalexin-like properties against Erwinia amylovora and other plant pathogens. European Journal of Plant Pathology 112 (2005) 133-142
16. Timbury M. Notes on Medical Virology. 11 ed. (1997), Churchill Livingstone, New York Cap. 11. pp. 593-609
17. Vanden Berghe D.A., Vlietinck A.J., and Van Hoof L. Plant products as potential antiviral agents. Bulletin Institute Pasteur 84 (1986) 101-147
18. Vlietinck A.J., De Bruyne T., Apers S., and Pieters L.A. Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection. Planta Medica 64 (1998) 97-109
19. Xu Z., Hollingshead M.G., Borgel S., Elder C., Khilevich A., and Flavin A.T. In vivo anti-HIV activity of (+)-calanolide a in the hollow fiber mouse model. Bioorganic and Medicinal Chemistry Letters 9 (1999) 133-138