Analysis and optimization of enantioselective extraction in a multi-product environment with a multistage equilibrium model

Chemical Engineering and Processing: Process Intensification

Volumn 46, Issue 10, 2007, Pages 996-1005

  Steensma, Maartje ^a   Kuipers, Norbert J M ^a   de Haan, André B ^a   Kwant, Gerard ^b  

^a UNIVERSITY OF TWENTE   (Netherlands)

^b DSM RESEARCH   (Netherlands)

Author keywords

Enantiomer; Fractional extraction; Multistage modelling

Indexed keywords

ENANTIOMERS; ENANTIOSELECTIVITY; EXTRACTION; MATHEMATICAL MODELS; OPTIMIZATION; PH EFFECTS;

AMINO ALCOHOLS; EXTRACTION FACTORS; FRACTIONAL EXTRACTION; MULTISTAGE EQUILIBRIUM;

AMINO ACIDS;

AMINO ACIDS; ENANTIOMERS; ENANTIOSELECTIVITY; EXTRACTION; MATHEMATICAL MODELS; OPTIMIZATION; PH EFFECTS;

EID: 34548425130     PISSN: 02552701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cep.2007.05.008     Document Type: Article

References (20)

1. Lo T.C., Baird M.H.I., and Hanson C. Handbook of Solvent Extraction (1983), Wiley-Interscience, New York
2. Takeuchi T., Horikawa R., and Tanimura T. Enantioselective solvent extraction of neutral dl amino acids in two-phase systems containing N-n-alkyl-l-proline derivatives and copper(II) ion. Anal. Chem. 56 (1984) 1152-1155
3. Ding H.B., Carr P.W., and Cussler E.W. Racemic leucine separation by hollow-fiber extraction. A.I.Ch.E.J. 38 (1992) 1493-1498
4. Yokouchi Y., Ohno Y., Nakagomi K., Tanimura T., and Kabasawa Y. A device for countercurrent fractional extraction and its application to continuous resolution of d,l-isoleucine. Chromatography 19 (1998) 374-375 In Japanese
5. Tsukube H., Uenishi J., Kanatani T., Itoh H., and Yonemitsu O. Enantioselective binding and extraction of zwitterionic amino acids by chiral lanthanide complexes. Chem. Comm. 4 (1996) 477-478
6. Pietrasckiewicz M., Kozbial M., and Pietraszkiewicz O. Chiral discrimination of amino acids and their potassium or sodium salts by optically active crown ether derived from d-mannose. J. Membr. Sci. 138 (1998) 109-113
7. Pickering P.J., and Chaudhuri J.B. Equilibrium and kinetic studies of the enantioselective complexation of (d/l)-phenylalanine with copper(II) N-decyl (l) hydroxyproline. Chem. Eng. Sci. 52 (1997) 377-386
8. Abe Y., Shoji T., Kobayashi M., Qing W., Asai N., and Nishizawa H. Enantioselective distribution of amino-alcohols in a liquid-liquid two-phase system containing dialkyl l-tartrate and boric acid. Chem. Pharm. Bull. 43 (1995) 262-265
9. Abe Y., Shoji T., Fukui S., Sasamoto M., and Nishizawa H. Enantioseparation by dual-flow countercurrent extraction: its application to the enantioseparation of (±)propanolol. Chem. Pharm. Bull. 44 (1996) 1521-1524
10. Prelog V., Stojanac Z., and Kovacevic K. Über die Enantiomerentrennung durch Verteilung zwischen flüssigen Phasen. Helv. Chim. Acta 65 (1982) 377-384
11. Prelog V., Mutak S., and Kovacevic K. Über die Enantiomerentrennung durch Verteilung zwischen flüssigen Phasen, 3. Mitteilung, Selektivität der lipophilen Weinsaüreester für chirale Ammonium-Salze verschiedener Konstitution und Konfiguration. Helv. Chim. Acta 66 (1983) 2279-2284
12. Prelog V., Kovacevic M., and Egli M. Lipophilic tartaric acid esters as enantioselective ionophores. Angew. Chem. Int. Ed. 28 (1989) 1147-1152
13. Steensma M., Kuipers N.J.M., de Haan A.B., and Kwant G. Identification of enantioselective extractants for chiral separation of amines and aminoalcohols. Chirality 18 (2006) 314-328
14. Steensma M., Kuipers N.J.M., de Haan A.B., and Kwant G. Influence of process parameters on extraction equilibria for the chiral separation of amines and amino-alcohols with a chiral crown ether. J. Chem. Technol. Biotechnol. 81 (2006) 588-597
15. Steensma M., Kuipers N.J.M., de Haan A.B., and Kwant G. Modelling and experimental evaluation of reaction kinetics in reactive extraction for chiral separation of amines, amino acids and amino-alcohols. Chem. Eng. Sci. 62 (2007) 1395-1407
16. Sheldon R.A. Chirotechnology, industrial synthesis of optically active compounds (1993), Marcel Dekker Inc.
17. Perry R.H., Green D.W., and Maloney J.O. Perry's Chemical Engineers' Handbook. seventh ed. (1997), McGraw-Hill, New York
18. Robbins L.A. Liquid-liquid extraction. In: Schweitzer P.A. (Ed). Handbook of Separation Technology for Chemical Engineers. 3rd ed. (1997), McGraw-Hill, New York 419-447
19. Takeuchi T., Horikawa R., Tanimura T., and Kabasawa Y. Resolution of dl-valine by countercurrent solvent extraction with continuous sample feeding. Sep. Sci. Tech. 25 (1990) 941-951
20. Nishizawa H., Tahara K., Hayashida A., and Abe Y. Continuous separation method with liquid particle extractor: enantioseparation of (±)-mandelic acid. Anal. Sci. 9 (1993) 611-615