Uptake and metabolism of novel biodegradable poly (glycerol-adipate) nanoparticles in DAOY monolayer

Journal of Controlled Release

Volumn 116, Issue 3, 2006, Pages 314-321

  Meng, W ^a   Parker, T L ^a   Kallinteri, P ^a   Walker, D A ^b   Higgins, S ^c   Hutcheon, G A ^c   Garnett, M C ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b QUEEN S MEDICAL CENTRE   (United Kingdom)

^c LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Biodegradable polymer; Nanoparticle degradation; Nanoparticle uptake; Parenteral delivery; Poly (glycerol adipate)

Indexed keywords

CELLS; METABOLISM; NANOSTRUCTURED MATERIALS; ORGANIC POLYMERS; TUMORS;

NANOPARTICLE DEGRADATION; NANOPARTICLE UPTAKE; PARENTERAL DELIVERY; POLY (GLYCEROL-ADIPATE);

CONTROLLED DRUG DELIVERY;

BIOMATERIAL; FLUORESCENT DYE; POLYGLYCEROL ADIPATE; POLYMER; RHODAMINE B;

ARTICLE; BIODEGRADABILITY; BIODEGRADATION; CELL LINE; CELL TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG METABOLISM; DRUG UPTAKE; ENDOSOME; FRACTIONATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LYSOSOME; MEDULLOBLASTOMA; MONOLAYER CULTURE; NANOPARTICLE; PRIORITY JOURNAL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; DRUG CARRIERS; ENDOSOMES; FLOW CYTOMETRY; HUMANS; LYSOSOMES; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PARTICLE SIZE; POLYESTERS; SOLUBILITY; SURFACE PROPERTIES;

EID: 34548418880     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.09.014     Document Type: Article

References (22)

1. Leger J.M., Ries L.A., Smith M.A., Warren J.L., Heineman E.F., Kaplan R.S., and Linet M.S. Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality. J. Natl. Cancer Inst. 91 (1999) 1382-1390
2. Rorke L. The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors. J. Neuropathol. Exp. Neurol. 42 (1983) 1-15
3. Castello M.A., Clerico A., Deb G., Dominici C., Fidani P., and Donfrancesco A. High-dose carboplatin in combination with etoposide (JET regimen) for childhood brain tumors. Am. J. Pediatr. Hematol./Oncol. 12 (1990) 297-300
4. Schuler D., Somlo P., Koos R., Kalmanchey R., and Paraicz E. Treatment of malignant scala posterior brain tumors in children: the chemotherapy of relapsed medulloblastoma with a dibromdulcitol containing drug regime and pharmacokinetic studies of dibromdulcitol in children. Med. Pediatr. Oncol. 20 (1992) 312-314
5. Borsi J.D., Csaki C., Ferencz T., and Oster W. Administration of Ethyol (amifostine) to a child with medulloblastoma to ameliorate hematological toxicity of high dose carboplatin. Anticancer Drugs 7 (1996) 121-126
6. Maeda H., Wu J., Swawa T., Matsumura Y., and Hori K. Tumor vascular permeability and EPR effect in macromolecular therapeutics: a review. J. Control. Release 65 (2000) 271-284
7. Duncan R., and Sat Y.-N. Tumor targeting by enhanced permeability and retention (EPR) effect. Ann. Oncol. 9 (1998) 39-50
8. Monsky W.L., Fukumura D., Gohongi T., Ancukiewcz M., Weich H.A., Torchilin V.P., Yuan R.M.F., and Jain R.K. Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res. 59 (1999) 4129-4135
9. Leo E., Brina B., Forni F., and Angela M. In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form. Int. J. Pharm. 278 (2004) 133-141
10. Govender T., Stolnik S., Garnett M.C., Illum L., and Davis S.S. PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J. Control. Release 57 (1999) 171-185
11. Cascone M.G., Pot P.M., Lazzeri L., and Zhu Z. Release of dexamethasone from PLGA nanoparticles entrapped into dextran/poly(vinylalcohol) hydrogels. J. Mater. Sci., Mater. Med. 13 (2002) 265-269
12. Redhead H.M., Davis S.S., and Illum L. Drug delivery in poly(lactide-co-glycolide) nanoparticles surface modified with poloxamer 407 and poloxamine 908: in vitro characterisation and in vivo evaluation. J. Control. Release 70 (2001) 353-363
13. Avgoustakis K., Beletsi A., Panagi Z., Klepetsanis P., Karydas A.G., and Ithakissios D.S. PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticles degradation, in vitro drug release and in vivo residence in blood properties. J. Control. Release 79 (2002) 123-135
14. Barichello J.M., Morishita M., Takayama K., and Nagai T. Absorption of insulin from pluronic F-127 gels following subcutaneous administration in rats. Int. J. Pharm. 184 (1999) 189-198
15. Kallinteri P., Higgins S., Hutcheon G.A., and St Pourçain C.B. Novel functionalized biodegradable polymers for nanoparticle drug delivery systems. Biomacromolecules 6 (2005) 1885-1894
16. Panyam J., Sahoo S.K., Prabha S., Bargar T., and Labhasetwar V. Fluorescence and electron microscopy probes for cellular and tissue uptake of poly (d, l-lactide-co-glycolide) nanoparticles. Int. J. Pharm. 262 (2003) 1-11
17. Panyam J., and Labhasetwar V. Dynamics of endocytosis and exocytosis of poly (d, l-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells. Pharm. Res. 20 (2003) 210-218
18. Garnett M.C., and Baldwin R.W. Endocytosis of a monoclonal antibody recognising a cell surface glycoprotein antigen visualised using fluorescent conjugates. Eur. J. Cell Biol. 41 (1986) 214-221
19. Fessi H., Puisieux F., Devissaguet J.P., Ammoury N., and Benita S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int. J. Pharm. 55 (1989) R1-R4
20. Van Deurs B., Petersen O.W., Olsnes S., and Sandvig K. The ways of endocytosis. Int. Rev. Cytol. 17 (1989) 131-177
21. Gibbs E.M., and Lienhard G.E. Fluid-phase endocytosis by isolated rat adipocytes. J. Cell. Physiol. 121 (1984) 569-575
22. Steinman R.M., Brodie S.E., and Cohn Z.A. Membrane flow during pinocytosis. A stereologic analysis. J. Cell Biol. 68 (1976) 665-687