Novel cyanoketene N,S-acetals and pyrazole derivatives using potassium 2-cyanoethylene-1-thiolates

Synthetic Communications

Volumn 37, Issue 17, 2007, Pages 2827-2834

  Elgemeie, Galal H ^a   Elghandour, Ahmed H ^b   Elaziz, Ghada W Abd ^b  

^a Helwan University   (Egypt)

^b BENI SUEF UNIVERSITY   (Egypt)

Author keywords

Activated nitriles; Cyano ketene N,S acetals; Cyanoacetamide; Cyanothioacetamide; Phenylisothiocyanate; Pyrazoles

Indexed keywords

CYANOKETENE N, ACETAL; KETENE DERIVATIVE; METHYL IODIDE; PHENYL ISOTHIOCYANATE; POTASSIUM HYDROXIDE; PYRAZOLE DERIVATIVE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE;

EID: 34548414138     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910701473317     Document Type: Article

References (3)

1. Elgemeie, G. H.; Elghandour, A. H.; Elzanate, A. M.; Ahmed, S. A. Novel synthesis of thioguanine and sulfanylpurine analogues: Reaction of heterocyclic ketene dithioacetals with nucleophiles. J. Chem. Res., Synop. 1998, 162-163.
2. Elgemeie, G. H.; El-Ezbawy, S. R.; El-Aziz, H. A. The design and synthesis of structurally related mercaptopurine analogues: Reaction of dimethyl N-cyanodithioiminocarbonate with 5-aminopyrazoles. Synth. Commun. 2001, 31, 3453-3458.
3. Elgemeie, G. H.; Elghandour, A. H.; Elzanate, A. M.; Ahmed, S. A. Synthesis of some novel α-cyanoketene S,S-acetals and their use in heterocyclic synthesis. J. Chem. Soc., Perkin Trans. 1997, 1, 3285-3289.