Studies on culture age versus exometabolite production in batch cultures of the cyanobacterium Nostoc insulare

Journal of Applied Phycology

Volumn 19, Issue 5, 2007, Pages 491-495

  Volk, Rainer B ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

4,4 dihydroxybiphenyl; Antimicrobial activity; Fermenter batch cultivation; Microalgal culture medium extracts; N,N (4,5 dimethyl 1,2 phenylene)bis acetamide; Norharmane (9H pyrido(3,4 b)indole)

Indexed keywords

BACTERIA (MICROORGANISMS); NOSTOC; NOSTOC SP.;

EID: 34548400782     PISSN: 09218971     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10811-007-9161-z     Document Type: Article

References (30)

1. Armstrong JE, Janda KE, Alvarado B, Wright AE (1991) Cytotoxin production by the marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor. J Appl Phycol 3:277-282
2. Asthana RK, Srivastava A, Singh AP, Deepali, Singh SP, Nath G, Srivastava R, Srivastava BS (2006) Identification of an antimicrobial entity from the cyanobacterium Fisherella sp. Isolated from bark of Azadirachta indica (Neem) tree. J Appl Phycol 18:33-39
3. Becker EW (1994) Growth conditions. In: Becker EW (ed) Microalgae-biotechnology and microbiology, Chapter 8. Cambridge University Press, Cambridge, UK, pp 51-55
4. Blom JF, Brütsch T, Barbaras D, Bethuel Y, Locher, HH, Hubschwerlen C, Gademann K (2006) Potent algicides based on the cyanobacterial alkaloid nostocarboline. Org Lett 8:737-740
5. Bloor S, England RR (1989) Antibiotic production by the cyanobacterium Nostoc muscorum. J Appl Phycol 1:367-372
6. Borowitzka MA (1995) Microalgae as sources of pharmaceuticals and other biologically active compounds. J Appl Phycol 10:3-15
7. Burja AM, Banaigs B, Abou-Mansour E, Burgess JG, Wright PC (2001) Marine cyanobacteria-a prolific source of natural products. Tetrahedron 57:9347-9377
8. Chetsumon A, Maeda I, Umeda F, Yagi K, Miura Y, Mizoguchi T (1995) Continuous antibiotic production by an immobilized cyanobacterium in a seaweed-type bioreactor. J Appl Phycol 7:135-139
9. Falch BS, König GM, Wright AD, Sticher O, Angerhofer CK, Pezzuto JM, Bachmann H (1995) Biological activities of cyanobacteria: Evaluation of extracts and pure compounds. Planta Med 61:321-328
10. Flores E, Wolk CP (1986) Production, by filamentous, nitrogen-fixing cyanobacteria, of a bacteriocin and of other antibiotics that kill related strains. Arch Microbiol 145:215-219
11. Hirata K, Nakagami H, Takashina J, Muhmud T, Kobayashi M, In Y, Ishida T, Miyamoto K (1996) Novel Violet Pigment, Nostocine A, an Extracellular Metabolite from Cyanobacterium Nostoc spongiaeforme. Heterocycles 43:1513-1519
12. Hirata K, Yoshitomi S, Dwi S, Iwabe O, Mahakhant A, Polchai J, Miyamoto K (2003) Bioactivities of nostocine a produced by a freshwater cyanobacterium Nostoc spongiaeforme TISTR 8 169. J Biosci Bioeng 95:512-517
13. Jaki B, Orjala J, Heilmann J, Linden A, Vogler B, Sticher O (2000) Novel extracellular diterpenoids with biological activity from the cyanobacterium Nostoc commune. J Nat Prod 63:339-343
14. Jaki B, Orjala J, Sticher O (1999) A novel extracellular diterpenoid with antibacterial activity from the cyanobacterium Nostoc comune. J Nat Prod 62:502-503
15. Jaki B, Zerbe O, Heilmann J, Sticher O (2001) Two novel cyclic peptides with antifungal activity from the cyanobacterium Tolypothrix byssoidea (EAWAG 195). J Nat Prod 63:154-158
16. Ördog V, Stirk WA, Lenobel R, Bancířová M, Strnad M, van Staden J, Szigeti J, Németh L (2004) Screening microalgae for some potentially useful agricultural and pharmaceutical secondary metabolites. J Appl Phycol 16:309-314
17. Piccardi R, Frosini A, Tredici MR, Margheri MC (2000) Bioactivity in free-living and symbiotic cyanobacteria of the genus Nostoc. J Appl Phycol 12:543-547
18. Piorreck M, Baasch KH, Pohl P (1984) Biomass production, total protein, chlorophylls, lipids and fatty acids of freshwater green and blue-green algae under different nitrogen regimes. Phytochemistry 23:207-216
19. Piorreck M, Pohl P (1984) Formation of biomass, total protein, chlorophylls, lipids and fatty acids in green and blue-green algae during one growth phase. Phytochemistry 23:217-223
20. Pohl P, Kohlhase M, Krautwurst S, Baasch KH (1987) An inexpensive inorganic culture medium for the mass cultivation of freshwater microalgae. Phytochemistry 26:1657-1659
21. Pohl P, Kohlhase M, Martin M (1988) Photobioreactors for the axenic mass cultivation of microalgae. In: Stadler T, Mollion J, Verdus M-C, Karamanos Y, Morvan H, Christiaen D (eds.) Algal Biotechnology. Elsevier, London, pp 209-217
22. Schlegel I, Doan NT, de Chazal N, Smith GD (1998) Antibiotic activity of new cyanobacterial isolates from Australia and Asia against green algae and cyanobacteria. J Appl Phycol 10:471-479
23. Schlösser UG (1994) SAG-Sammlung von Algenkulturen at the University of Göttingen. Bot Acta 107:113-186
24. Schwartz RE, Hirsch CF, Sesin DF, Flor JE, Chartrain M, Fromtling RE, Harris GH, Salvatore MJ, Liesch JM, Yudin K (1990) Pharmaceuticals from cultured algae. J Ind Microbiol 5:113-124
25. Tjahjono AE, Hayama Y, Kakizono T, Terada Y, Nishio N, Nagai S (1994) Hyper-accumulation of astaxanthin in a green alga Haematococcus pluvialis at elevated temperatures. Biotechnol Lett 16:133-138
26. Volk R-B (2005) Screening of microalgal culture media for the presence of algicidal compounds and isolation and identification of two bioactive metabolites, excreted by the cyanobacteria Nostoc insulare and Nodularia harveyana, respectively. J Appl Phycol 17:339-347
27. Volk R-B, Furkert FH (2006) Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth. Microbiol Res 161:180-186
28. Volk R-B, Mundt S (2006) Cytotoxic and non-cytotoxic exometabolites of the cyanobacterium Nostoc insulare. J Appl Phycol, published online, doi: 10.1007/s10811-006-9110-2
29. Wada H, Murata N (1990) Temperature-induced changes in the fatty acid composition of the cyanobacterium, Synechocystis PCC68O3. Plant Physiol 92:1062-1069
30. Watanabe MF, Harada KI, Matsuura K, Watanabe M, Suzuki M (1989) Heptapeptide toxin production during the batch culture of two Microcystis species (Cyanobacteria). J Appl Phycol 1:161-165