No evidence for plasminogen activator inhibitor 1 4G/4G genotype as risk factor for cerebral venous thrombosis [5]

Journal of Neurology

Volumn 254, Issue 8, 2007, Pages 1124-1125

  Lichy, Christoph ^a   Kloss, Manja ^a   Reismann, Peter ^a   Genius, Just ^b   Grau, Armin ^c   Reuner, Karl ^d  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c Dept of Neurology   (Germany)

^d STÄDTISCHES KLINIKUM KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1;

ADULT; BRAIN ISCHEMIA; CONTROLLED STUDY; DEMOGRAPHY; DNA POLYMORPHISM; FEMALE; FIBRINOLYSIS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; RISK FACTOR; VASCULAR DISEASE; VEIN THROMBOSIS;

ADULT; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM, GENETIC; RISK FACTORS; SINUS THROMBOSIS, INTRACRANIAL;

EID: 34548397673     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-006-0417-3     Document Type: Letter

References (6)

1. Sartori MT, Wiman B, Vettore S, Dazzi F, Girolami A, Patrassi GM (1998) 4g/5g polymorphism of pai-1 gene promoter and fibrinolytic capacity in patients with deep vein thrombosis. Thromb Haemost 80:956-960
2. Wiklund PG, Nilsson L, Ardnor SN, Eriksson P, Johansson L, Stegmayr B, Hamsten A, Holmberg D, Asplund K (2005) Plasminogen activator inhibitor-1 4g/5g polymorphism and risk of stroke: Replicated findings in two nested casecontrol studies based on independent cohorts. Stroke 36:1661-1665
3. Junker R, Nabavi DG, Wolff E, Ludemann P, Nowak-Gottl U, Kase M, Baumer R, Ringelstein EB, Assmann G (1998) Plasminogen activator inhibitor-1 4g/4g-genotype is associated with cerebral sinus thrombosis in factor v leiden carriers. Thromb Haemost 80:706-707
4. Lichy Ch, Dong-Si T, Reuner K, Genius J, Rickmann H, Hampe T, Dolan T, Stoll F, Grau A (2006) Risk of cerebral venous thrombosis and novel gene polymorphisms of the coagulation and fibrinolytic systems. J Neurol 253:316-320
5. Margaglione M, Grandone E, Cappucci G, Colaizzo D, Giuliani N, Vecchione G, d'Addedda M, Di Minno G (1997) An alternative method for pai-1 promoter polymorphism (4g/5g) typing. Thromb Haemost 77:605-606
6. Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Miletich JP (1997) Arterial and venous thrombosis is not associated with the 4g/5g polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of us men. Circulation 95:59-62