Sulfated polysaccharide purified from Ecklonia cava accelerates antithrombin III-mediated plasma proteinase inhibition

Journal of Applied Phycology

Volumn 19, Issue 5, 2007, Pages 425-430

  Jung, Won Kyo ^a,f   Athukorala, Yasantha ^b   Lee, Young Jae ^b   Cha, Seon Heui ^b   Lee, Chi Ho ^c   Vasanthan, Thava ^d   Choi, Kwang Sik ^b   Yoo, Sang Ho ^e   Kim, Se Kwon ^a   Jeon, You Jin ^b  

^a Pukyong National University   (South Korea)

^b Jeju National University   (South Korea)

^c Konkuk University   (South Korea)

^d UNIVERSITY OF ALBERTA   (Canada)

^e Sejong University   (South Korea)

^f LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Binding affinity; E. cava; Kinetic assay; Sulfated polysaccharide; Surface plasmon resonance

Indexed keywords

ECKLONIA CAVA; PHAEOPHYCEAE;

EID: 34548397216     PISSN: 09218971     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10811-006-9149-0     Document Type: Article

References (18)

1. Athukorala Y, Jung WK, Vasanthan T, Jeon YJ (2006a) An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava. Carbohydr Polym 66:184-191
2. Athukorala Y, Kim KN, Jeon YJ (2006b) Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food Chem Toxicol 44:1065-1074
3. Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB (1987) Evaluation of a tetrazolium-based semiautomatic colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47:936-942
4. Davie EW, Fujikawa K, Kisiel W (1991) The coagulation cascade: initiation, maintenance, and regulation. Biochemistry 30:10363-10370
5. Desai UR (2004) New antithrombin-based anticoagulants. Med Res Rev 24:151-181
6. Griffith MJ (1986) In: Zwaal RFP, Hemker HC (eds) Blood coagulation, Elsevier, Amsterdam, pp 259-283
7. Jordan RE, Oosta GM, Gardner WT, Rosenberg RD (1980) The kinetics of hemostatic enzyme-antithrombin interactions in the presence of low molecular weight heparin. J Biol Chem 255:10081-10090
8. Lawson JH, Butenas S, Ribarik N, Mann KG (1993) Complex-dependent inhibition of factor VIIa by antithrombin III and heparin. J Biol Chem 268:767-770
9. Lundblad RL, Kingdon HS, Mann KG (1976) Thrombin. Methods Enzymol 45:156
10. Matsubara K, Matsuura Y, Bacic A, Liao ML, Hori K, Miyazawa K (2001) Antiangiogenic properties of a sulfated galactan isolated from a marine green alga, Codium cylindricum. J Appl Phycol 126:3715-3723
11. Mossman T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
12. Nishino T, Aizu Y, Nagumo T (1991) Antithrombin activity of a fucan sulfate from the brown seaweed Ecklonia kurome. Thromb Res 62:765-773
13. Okai Y, Higashi-Okai K (1994) Identification of antimutagenic activities in the extracts of an edible brown alga, Hijikia fusiforme (Hijiki) by umu gene expression system in Salmonella typhimurium (TA 1535/pSK 1002). J Sci Food Agric 66:103-109
14. Okai Y, Higashi-Okai K, Nakamura S (1993) Identification of heterogeneous antimutagenic activities in the extract of edible brown seaweeds, Laminaria japonica (Makonbu) and Undaria pinnatifda (Wakame) by umu gene expression system in Salmonella typhimurium (TA 1535/pSK 1002). Mutat Res 302:63-70
15. Olson ST, Bjork I, Shore JD (1993) Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin. Methods Enzymol 222:525-559
16. Rosenberg RD, Rosenberg JS (1984) Natural anticoagulant mechanisms. J Clin Invest 74:1-6
17. Shanmugam S, Mody KH (2000) Heparonid active sulfated polysaccharides from marine algae as potential blood coagulant agents. Curr Sci 79:1672-1683
18. Shobe J, Dickinson CD, Edgington TS, Ruf W (1999) Macromolecular substrate affinity for the tissue factor-factor VIIa complex is independent of scissile bond docking. J Biol Chem 274:24171-24175