Is the presence of antibodies in CSF sufficient to make a definitive diagnosis of Lyme disease?

Neurology

Volumn 69, Issue 10, 2007, Pages 949-950

  Roos, Karen L ^a,c   Berger, Joseph R ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTRIAXONE; DOXYCYCLINE;

BACTERIUM DETECTION; BORRELIA BURGDORFERI; CEREBROSPINAL FLUID; EDITORIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN BLOOD LEVEL; LYME DISEASE; MENINGITIS; PRIORITY JOURNAL; RADICULOPATHY; SEROLOGY; SYMPTOMATOLOGY; UNITED STATES; WESTERN BLOTTING;

ANTIBODIES, BACTERIAL; BORRELIA BURGDORFERI; HUMANS; LYME DISEASE;

EID: 34548397131     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000271901.94853.24     Document Type: Editorial

References (5)

1. Wormser GP, Dattwyler RJ, Shapiro ED, et al. The clinical assessment, treatment and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 2006;43:1089-1034.
2. Centers for Disease Control and Prevention. Case definitions for infectious conditions under public health surveillance: Lyme disease. Morb Mortal Wkly Rep 1997;46:1-64.
3. Blanc F, Jaulhac B, Fleury M, et al. Relevance of the antibody index to diagnose Lyme neuroborreliosis among seropositive patients. Neurology 2007;69:953-958
4. Wilske B, Schierz G, et al. Intrathecal production of specific antibodies against Borrelia burgdorferi in patients with lymphocytic meningoradiculitis (Bannwarth's syndrome). J Infect Dis 1986;153:304-314.
5. Karlsson M, Hammers-Berggren S, Lindquist L, Stiernstedt G, Svenungsson B. Comparison of intravenous penicillin G and oral doxycycline for treatment of Lyme neuroborreliosis. Neurology 1994;44:1203-1207.