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Volumn 64, Issue 3, 2007, Pages 227-231
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Cyclization of thiosemicarbazide derivatives of 5-arylidene-2,4- dioxothiazolidine-3-acetic acids to 1,3,4-thiadiazoles and their pharmacological properties
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Author keywords
1,3,4 thiadiazole; 5 arylidene 2,4 dioxothiazolidine 3 acetic acid; Cyclization; Pharmacological screening; Thiosemicarbazides
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Indexed keywords
(2,4 DIOXOTHIAZOLIDIN 3 YL) CHLORIDE DERIVATIVE;
1,3,4 THIADIAZOLE DERIVATIVE;
2,4 DIOXOTHIAZOLIDINE 3 ACETIC ACID DERIVATIVE;
4 PHENYLTHIOSEMICARBAZIDE DERIVATIVE;
5 (4 BROMOBENZYLIDENE) 2,4 DIOXO 3 [(5 PHENYLAMINE 1,3,4 THIADIAZOL 2 YL)METHYL]THIAZOLIDINE;
5 (4 METHOXYBENZYLIDENE) 2,4 DIOXO 3 [(5 PHENYLAMINE 1,3,4 THIADIAZOL 2 YL)METHYL]THIAZOLIDINE;
ACETIC ACID;
ACYLTHIOSEMICARBAZIDE DERIVATIVE;
HYDROCHLORIC ACID;
SULFURIC ACID;
THIOSEMICARBAZIDE DERIVATIVE;
UNCLASSIFIED DRUG;
ACETIC ACID DERIVATIVE;
ANALGESIC AGENT;
SEMICARBAZIDE DERIVATIVE;
THIADIAZOLE DERIVATIVE;
ANALGESIC ACTIVITY;
ANIMAL EXPERIMENT;
ARTICLE;
BEHAVIOR;
CARBON NUCLEAR MAGNETIC RESONANCE;
CENTRAL NERVOUS SYSTEM;
CHEMICAL REACTION;
CONTROLLED STUDY;
CYCLIZATION;
DRUG STRUCTURE;
DRUG SYNTHESIS;
INFRARED SPECTROMETRY;
LETHAL DOSE;
MASS SPECTROMETRY;
MOUSE;
NONHUMAN;
PROTON NUCLEAR MAGNETIC RESONANCE;
STATISTICAL ANALYSIS;
TRANQUILIZING ACTIVITY;
ANIMAL;
CHEMISTRY;
DOSE RESPONSE;
DRUG EFFECT;
FEMALE;
INTRAPERITONEAL DRUG ADMINISTRATION;
LD 50;
MALE;
PAIN;
PAIN ASSESSMENT;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
TOXICITY TESTING;
ACETIC ACIDS;
ACUTE TOXICITY TESTS;
ANALGESICS;
ANIMALS;
CENTRAL NERVOUS SYSTEM;
CYCLIZATION;
DOSE-RESPONSE RELATIONSHIP, DRUG;
FEMALE;
INJECTIONS, INTRAPERITONEAL;
LETHAL DOSE 50;
MALE;
MICE;
PAIN;
PAIN MEASUREMENT;
SEMICARBAZIDES;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIADIAZOLES;
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EID: 34548396780
PISSN: 00016837
EISSN: None
Source Type: Journal
DOI: None Document Type: Article |
Times cited : (8)
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References (36)
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