Sustaining the engine of U.S. biomedical discovery

New England Journal of Medicine

Volumn 357, Issue 10, 2007, Pages 1042-1047

  Heinig, Stephen J ^a   Krakower, Jack Y ^a   Dickler, Howard B ^a   Korn, David ^a  

^a ASSOCIATION OF AMERICAN MEDICAL COLLEGES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; BUDGET; COST EFFECTIVENESS ANALYSIS; ECONOMIC ASPECT; FUNDING; HEALTH CARE FACILITY; HEALTH SURVEY; HUMAN; MEDICAL INSTRUMENTATION; MEDICAL RESEARCH; MEDICAL SCHOOL; MEDICAL SERVICE; PRIORITY JOURNAL; REVIEW; UNITED STATES;

EID: 34548385771     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMsb071774     Document Type: Editorial

References (30)

1. Summary of the FY 2008 President's budget. Bethesda, MD: National Institutes of Health, February 5, 2007. (Accessed August 16, 2007, at http://www.nih.gov/about/director/budgetrequest/pressinfofy2008.pdf.)
2. The NIH almanac - appropriations. Bethesda, MD: National Institutes of Health. (Accessed August 16, 2007, at http://www.nih.gov/about/almanac/ appropriations/part2.htm.)
3. NIH Office of Budget. Biomedical research and development price index (BRDPI). Bethesda, MD: National Institutes of Health, February 5, 2007. (Accessed August 16, 2007, at http://officeofbudget.od.nih.gov/UI/ GDP_FromGenBudget.htm.)
4. Zerhouni EA. Research funding: NIH in the post doubling era: realities and strategies. Science 2006;314:1088-90.
5. Bishop JM, Varmus H. Re-aim blame for NIH's hard times. Science 2006;312:499.
6. Nathan DG, Schechter AN. NIH support for basic clinical research: biomedical researcher angst in 2006. JAMA 2006;295:2656-8.
7. NIH new investigators program. Bethesda. MD: National Institutes of Health. (Accessed August 16, 2007, at http://grants.nih.gov/grants/ new_investigators/index.htm.)
8. NIH awards to medical schools by rank, FY 2005. Bethesda, MD: National Institutes of Health. (Accessed August 16, 2007, at http://grants1.nih.gov/ grants/award/rank/medttl05.htm.)
9. The Medical School Profile System (MSPS). Washington, DC: Association of American Medical Colleges. (Accessed August 16, 2007, at http://www.aamc.org/ data/msps/start.htm.)
10. NIH at the crossroads: myths, realities, and strategies for the future. Presentation by Elias Zerhouni, M.D., to the NIH Advisory Committee to the Director, 2006. (Accessed August 16, 2007, at http://grants1.nih.gov/grants/ award/NIH_at_the_Crossroads.ppt.)
11. Korn D, Rich RR, Garrison HH, et al. Science policy: the NIH budget in the "postdoubling" era. Science 2002;296:1401-2.
12. Garrison HH, Palazzo RE. What's happening to the new investigators? FASEB J 2006;20:1288-9.
13. Dickler HB, Korn D, Gabbe SG. Promoting translational and clinical science: the critical role of medical schools and teaching hospitals. PLoS Med 2006;3(9):e378.
14. National Research Council. Bridges to independence: fostering the independence of new investigators in biomedical research. Washington, DC: National Academies Press, 2005.
15. Wyngaarden JB. The clinical investigator as an endangered species. N Engl J Med 1979;301:1254-9.
16. Sung NS, Crowley WF, Genel M, et al. Central challenges facing the national clinical research enterprise. JAMA 2003;289:1278-87.
17. AAMC Task Force II on Clinical Research. Promoting translational and clinical science: the critical role of medical schools and teaching hospitals. Washington, DC: Association of American Medical Colleges, 2006. (Accessed August 16, 2007, at http://www.aamc.org/promotingclinicalscience.)
18. Korn D. Academic medicine in an era of resource constraints. In: Snyderman R, Saito VY, eds. The academic health center in the 21st Century: 1995 Duke Private Sector Conference. Durham, NC: Duke University Medical Center and Health System, 1995.
19. CBO's baseline budget projections (2008). Washington, DC: Congressional Budget Office. (Accessed August 16, 2007, at http://www.cbo.gov/budget/budproj. pdf.)
20. Normile D. Biomedical research: an Asian tiger's bold experiment. Science 2007;316:38-41.
21. Federal funding for biomedical and related life sciences research, FY 2008. Bethesda, MD: Federation of American Societies for Experimental Biology, 2007. (Accessed August 16, 2007, at http://opa.faseb.org/pdf/ final_funding_fy2008.pdf.)
22. National Institutes of Health Reform Act of 2006. P.L. 109-482.
23. Billingsley ML, Washko M. Maximizing state and federal spending while minimizing conflicts. Nat Biotechnol 2006;24:1473-4.
24. Bok D. Universities in the marketplace: the commercialization of higher education. Princeton, NJ: Princeton University Press, 2004.
25. Protecting subjects, preserving trust, promoting progress: policy and guidelines for the oversight of individual financial interests in human subjects research. Washington, DC: Association of American Medical Colleges, 2001. (Accessed August 16, 2007, at http://www.aamc.org/research/coi/firstreport.pdf.)
26. Protecting subjects, preserving trust, promoting progress II: principles and recommendations for oversight of an institution's financial interests in human subjects research. Washington, DC: Association of American Medical Colleges, 2002. (Accessed August 16, 2007, at http://www.aamc.org/research/coi/ 2002coireport.pdf.)
27. Murphy KM, Topel RH, eds. Measuring the gains from medical research. Chicago: University of Chicago Press, 2003.
28. McMillan GS, Narin F, Deeds DL. An analysis of the critical role of public science in innovation: the case of biotechnology. Res Policy 2000;29:1-8.
29. Woolley M, Propst SM. Public attitudes and perceptions about health-related research. JAMA 2005;294:1380-4.
30. Loscalzo J. The NIH budget and the future of biomedical research. N Engl J Med 2006;354:1665-7.