First-trimester ultrasound assessment of the nasal bone to screen for aneuploidy

Obstetrics and Gynecology

Volumn 110, Issue 2 I, 2007, Pages 399-404

  Rosen, Todd ^a   D'Alton, Mary E ^a   Platt, Lawrence D ^a   Wapner, Ronald ^a  

^a PH 16 66 ^*

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; BONE DEVELOPMENT; DISEASE MARKER; DOWN SYNDROME; FIRST TRIMESTER PREGNANCY; HIGH RISK POPULATION; HIGH RISK PREGNANCY; HUMAN; MATERNAL SERUM; MEDICAL LITERATURE; MULTIPLE PREGNANCY; NASAL BONE; NUCHAL TRANSLUCENCY MEASUREMENT; PRIORITY JOURNAL; QUALITY CONTROL; REVIEW; RISK ASSESSMENT; SCREENING; TRISOMY 13; TRISOMY 18; TRISOMY 21; ULTRASOUND; UNITED STATES; CONGENITAL MALFORMATION; ECHOGRAPHY; FEMALE; METHODOLOGY; PREGNANCY;

BIOLOGICAL MARKER;

ANEUPLOIDY; BIOLOGICAL MARKERS; FEMALE; HUMANS; NASAL BONE; NUCHAL TRANSLUCENCY MEASUREMENT; PREGNANCY; PREGNANCY TRIMESTER, FIRST; ULTRASONOGRAPHY, PRENATAL;

EID: 34548381372     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.AOG.0000275281.19344.66     Document Type: Review

References (20)

1. Cleary-Goldman J, Morgan MA, Malone FD, Robinson JN, D'Alton ME, Schulkin J. Screening for Down syndrome: practice patterns and knowledge of obstetricians and gynecologists. Obstet Gynecol 2006;107:11-7.
2. Rosen T, D'Alton ME. Down syndrome screening in the first and second trimesters: what do the data show? Semin Perinatol 2005;29:367-75.
3. Cicero S, Curcio P, Papageorghiou A, Sonek J, Nicolaides K. Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: an observational study. Lancet 2001;358:1665-7.
4. Cicero S, Rembouskos G, Vandecruys H, Hogg M, Nicolaides KH. Likelihood ratio for trisomy 21 in fetuses with absent nasal bone at the 11-14-week scan. Ultrasound Obstet Gynecol 2004;23:218-23.
5. Stempfle N, Huten Y, Fredouille C, Brisse H, Nessmann C. Skeletal abnormalities in fetuses with Down's syndrome: a radiographic post-mortem study. Pediatr Radiol 1999;29:682-8.
6. Tuxen A, Keeling JW, Reintoft I, Fischer Hansen B, Nolting D, Kjaer I. A histological and radiological investigation of the nasal bone in fetuses with Down syndrome. Ultrasound Obstet Gynecol 2003;22:22-6.
7. Kelekci S, Yazicioglu HF, Oguz S, Inan I, Yilmaz B, Sonmez S. Nasal bone is it useful? Gynecol Obstet Invest 2004;58:91-5.
8. Malone FD, Ball RH, Nyberg DA, Comstock CH, Saade G, Berkowitz RL, et al. First-trimester nasal bone evaluation for aneuploidy in the general population. Obstet Gynecol 2004;104:1222-8.
9. Monni G, Zoppi MA, Ibba RM, Floris M, Manca F, Axiana C. Nuchal translucency and nasal bone for trisomy 21 screening: single center experience. Croat Med J 2005;46:786-91.
10. Orlandi F, Rossi C, Orlandi E, Jakil MC, Hallahan TW, Macri VJ, et al. First-trimester screening for trisomy-21 using a simplified method to assess the presence or absence of the fetal nasal bone. Am J Obstet Gynecol 2005;192:1107-11.
11. Viora E, Masturzo B, Errante G, Sciarrone A, Bastonero S, Campogrande M. Ultrasound evaluation of fetal nasal bone at 11 to 14 weeks in a consecutive series of 1906 fetuses. Prenat Diagn 2003;23:784-7.
12. Otano L, Aiello H, Igarzabal L, Matayoshi T, Gadow EC. Association between first trimester absence of fetal nasal bone on ultrasound and Down syndrome. Prenat Diagn 2002;22:930-2.
13. Wong SF, Choi H, Ho LC. Nasal bone hypoplasia: is it a common finding amongst chromosomally normal fetuses of southern Chinese women? Gynecol Obstet Invest 2003;56:99-101.
14. Senat MV, Bernard JP, Boulvain M, Ville Y. Intra- and interoperator variability in fetal nasal bone assessment at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 2003;22:138-41.
15. Cicero S, Longo D, Rembouskos G, Sacchini C, Nicolaides KH. Absent nasal bone at 11-14 weeks of gestation and chromosomal defects. Ultrasound Obstet Gynecol 2003;22:31-5.
16. Prefumo F, Sairam S, Bhide A, Penna L, Hollis B, Thilaganathan B. Maternal ethnic origin and fetal nasal bones at 11-14 weeks of gestation. BJOG 2004;111:109-12.
17. Cicero S, Avgidou K, Rembouskos G, Kagan KO, Nicolaides KH. Nasal bone in first-trimester screening for trisomy 21. Am J Obstet Gynecol 2006;195:109-14.
18. Prefumo F, Sairam S, Bhide A, Thilaganathan B. First-trimester nuchal translucency, nasal bones, and trisomy 21 in selected and unselected populations. Am J Obstet Gynecol 2006;194:828-33.
19. Cicero S, Dezerega V, Andrade E, Scheier M, Nicolaides KH. Learning curve for sonographic examination of the fetal nasal bone at 11-14 weeks. Ultrasound Obstet Gynecol 2003;22:135-7.
20. Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O. Multicenter study of first-trimester screening for trisomy 21 in 75,821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obstet Gynecol 2005;25:221-6.