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Volumn 20, Issue 5, 2007, Pages 535-548

Overexpression of non-functional LAT1/4F2hc in renal proximal tubular epithelial cells from the spontaneous hypertensive rat

Author keywords

4F2hc; Hypertension; L leucine; LAT1; Sodium

Indexed keywords

2 AMINOBICYCLO(2,2,1) HEPTANE 2 CARBOXYLIC ACID; 4F2HC PROTEIN; ALANYLALANYLTHREONYLALANYLTHREONYLCYSTEINYLALANYLCYSTEINYLAL ANYLCYSTEINYLTHREONYLGLYCYLALANYLTHREONYLCYSTEINYLALANYLALANYLTHREONYL GLYCYLGLYCYLTHREONYLCYSTEINE; AMINO ACID TRANSPORTER; AMINO ACID TRANSPORTER TYPE 1; CARBOXYLIC ACID DERIVATIVE; GLYCOPROTEIN; LEUCINE C 14; RADIOISOTOPE; SMALL INTERFERING RNA; SODIUM; UNCLASSIFIED DRUG;

EID: 34548369605     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000107537     Document Type: Article
Times cited : (3)

References (31)
  • 1
    • 0141962631 scopus 로고    scopus 로고
    • Organ-specific overexpression of renal LAT2 and enhanced tubular L-DOPA uptake precede the onset of hypertension
    • Pinho MJ, Gomes P, Serrao MP, Bonifacio MJ, Soares-da-Silva P: Organ-specific overexpression of renal LAT2 and enhanced tubular L-DOPA uptake precede the onset of hypertension. Hypertension 2003;42:613-618.
    • (2003) Hypertension , vol.42 , pp. 613-618
    • Pinho, M.J.1    Gomes, P.2    Serrao, M.P.3    Bonifacio, M.J.4    Soares-da-Silva, P.5
  • 2
    • 0033861511 scopus 로고    scopus 로고
    • Salt intake and sensitivity of intestinal and renal Na+-K+ atpase to inhibition by dopamine in spontaneous hypertensive and Wistar-Kyoto rats
    • Lucas-Teixeira VA, Vieira-Coelho MA, Serrao P, Pestana M, Soares-da-Silva P: Salt intake and sensitivity of intestinal and renal Na+-K+ atpase to inhibition by dopamine in spontaneous hypertensive and Wistar-Kyoto rats. Clin Exp Hypertens 2000;22:455-469.
    • (2000) Clin Exp Hypertens , vol.22 , pp. 455-469
    • Lucas-Teixeira, V.A.1    Vieira-Coelho, M.A.2    Serrao, P.3    Pestana, M.4    Soares-da-Silva, P.5
  • 3
    • 0037087461 scopus 로고    scopus 로고
    • 0,+ , exchange L-DOPA with neutral and basic amino acids in two clonal renal cell lines
    • 0,+ , exchange L-DOPA with neutral and basic amino acids in two clonal renal cell lines. J Membr Biol 2002;186:63-80.
    • (2002) J Membr Biol , vol.186 , pp. 63-80
    • Gomes, P.1    Soares-da-Silva, P.2
  • 5
    • 2942670727 scopus 로고    scopus 로고
    • The dopamine precursor L-dihydroxyphenylalanine is transported by the amino acid transporters rBAT and LAT2 in renal cortex
    • Quinones H, Collazo R, Moe OW: The dopamine precursor L-dihydroxyphenylalanine is transported by the amino acid transporters rBAT and LAT2 in renal cortex. Am J Physiol Renal Physiol 2004;287:F74-F80.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Quinones, H.1    Collazo, R.2    Moe, O.W.3
  • 7
    • 3042844036 scopus 로고    scopus 로고
    • Overexpression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells
    • Pinho MJ, Serrao MP, Gomes P, Hopfer U, Jose PA, Soares-da-Silva P: Overexpression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells. Kidney Int 2004;66:216-226.
    • (2004) Kidney Int , vol.66 , pp. 216-226
    • Pinho, M.J.1    Serrao, M.P.2    Gomes, P.3    Hopfer, U.4    Jose, P.A.5    Soares-da-Silva, P.6
  • 8
    • 0031751209 scopus 로고    scopus 로고
    • Molecular biology of mammalian plasma membrane amino acid transporters
    • Palacin M, Estevez R, Bertran J, Zorzano A: Molecular biology of mammalian plasma membrane amino acid transporters. Physiol Rev 1998;78:969-1054.
    • (1998) Physiol Rev , vol.78 , pp. 969-1054
    • Palacin, M.1    Estevez, R.2    Bertran, J.3    Zorzano, A.4
  • 9
    • 0035210660 scopus 로고    scopus 로고
    • Heterodimeric amino acid transporters: Molecular biology and pathological and pharmacological relevance
    • Kanai Y, Endou H: Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. Curr Drug Metab 2001;2:339-354.
    • (2001) Curr Drug Metab , vol.2 , pp. 339-354
    • Kanai, Y.1    Endou, H.2
  • 12
    • 0034796442 scopus 로고    scopus 로고
    • Function and structure of heterodimeric amino acid transporters
    • Wagner CA, Lang F, Broer S: Function and structure of heterodimeric amino acid transporters. Am J Physiol Cell Physiol 2001;281:C1077-C1093.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Wagner, C.A.1    Lang, F.2    Broer, S.3
  • 14
    • 8944246321 scopus 로고    scopus 로고
    • Studies on the pharmacology of the inward transport of L-DOPA in rat renal tubules
    • Pinto-do-Ó PC, Soares-da-Silva P: Studies on the pharmacology of the inward transport of L-DOPA in rat renal tubules. Br J Pharmacol 1996;118:741-747.
    • (1996) Br J Pharmacol , vol.118 , pp. 741-747
    • Pinto-do-Ó, P.C.1    Soares-da-Silva, P.2
  • 15
    • 4444378493 scopus 로고    scopus 로고
    • Dopamine D3 receptor-mediated inhibition of Na+/H+ exchanger activity in normotensive and spontaneously hypertensive rat proximal tubular epithelial cells
    • Pedrosa R, Gomes P, Zeng C, Hopfer U, Jose PA, Soares-da-Silva P: Dopamine D3 receptor-mediated inhibition of Na+/H+ exchanger activity in normotensive and spontaneously hypertensive rat proximal tubular epithelial cells. Br J Pharmacol 2004;142:1343-1353.
    • (2004) Br J Pharmacol , vol.142 , pp. 1343-1353
    • Pedrosa, R.1    Gomes, P.2    Zeng, C.3    Hopfer, U.4    Jose, P.A.5    Soares-da-Silva, P.6
  • 16
    • 0029830096 scopus 로고    scopus 로고
    • Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats
    • Woost PG, Orosz DE, Jin W, Frisa PS, Jacobberger JW, Douglas JG, Hopfer U: Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats. Kidney Int 1996;50:125-134.
    • (1996) Kidney Int , vol.50 , pp. 125-134
    • Woost, P.G.1    Orosz, D.E.2    Jin, W.3    Frisa, P.S.4    Jacobberger, J.W.5    Douglas, J.G.6    Hopfer, U.7
  • 18
    • 0024332759 scopus 로고
    • Calculating receptor number from binding experiments using same compound as radioligand and competitor
    • DeBlasi A, O'Reilly K, Motulsky HJ: Calculating receptor number from binding experiments using same compound as radioligand and competitor. Trends Pharmacol Sci 1989;10:227-229.
    • (1989) Trends Pharmacol Sci , vol.10 , pp. 227-229
    • DeBlasi, A.1    O'Reilly, K.2    Motulsky, H.J.3
  • 19
    • 34548335388 scopus 로고    scopus 로고
    • Motulsky HJ: Analyzing Data with GraphPad Prism, Version 3.0 ed. GraphPad Prism Software, Inc, San Diego, CA 1999
    • Motulsky HJ: Analyzing Data with GraphPad Prism, Version 3.0 ed. GraphPad Prism Software, Inc., San Diego, CA 1999.
  • 20
    • 2642564455 scopus 로고    scopus 로고
    • Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder
    • Broer A, Klingel K, Kowalczuk S, Rasko JE, Cavanaugh J, Broer S: Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder. J Biol Chem 2004;279:24467-24476.
    • (2004) J Biol Chem , vol.279 , pp. 24467-24476
    • Broer, A.1    Klingel, K.2    Kowalczuk, S.3    Rasko, J.E.4    Cavanaugh, J.5    Broer, S.6
  • 22
    • 0033521614 scopus 로고    scopus 로고
    • + L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family
    • + L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family. Embo J 1999;18:49-57.
    • (1999) Embo J , vol.18 , pp. 49-57
    • Pfeiffer, R.1    Rossier, G.2    Spindler, B.3    Meier, C.4    Kuhn, L.5    Verrey, F.6
  • 24
    • 0032508585 scopus 로고    scopus 로고
    • Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)
    • Kanai Y, Segawa H, Miyamoto K, Uchino H, Takeda E, Endou H: Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). J Biol Chem 1998;273:23629-23632.
    • (1998) J Biol Chem , vol.273 , pp. 23629-23632
    • Kanai, Y.1    Segawa, H.2    Miyamoto, K.3    Uchino, H.4    Takeda, E.5    Endou, H.6
  • 25
    • 0037291723 scopus 로고    scopus 로고
    • System L: Heteromeric exchangers of large, neutral amino acids involved in directional transport
    • Verrey F: System L: heteromeric exchangers of large, neutral amino acids involved in directional transport. Pflugers Arch 2003;445:529-533.
    • (2003) Pflugers Arch , vol.445 , pp. 529-533
    • Verrey, F.1
  • 26
    • 8844263040 scopus 로고    scopus 로고
    • RNA interference-induced reduction in CD98 expression suppresses cell fusion during syncytialization of human placental BeWo cells
    • Kudo Y, Boyd CA: RNA interference-induced reduction in CD98 expression suppresses cell fusion during syncytialization of human placental BeWo cells. FEBS Lett 2004;577:473-477.
    • (2004) FEBS Lett , vol.577 , pp. 473-477
    • Kudo, Y.1    Boyd, C.A.2
  • 27
    • 13044258426 scopus 로고    scopus 로고
    • Selective expression of the large neutral amino acid transporter at the blood-brain barrier
    • Boado RJ, Li JY, Nagaya M, Zhang C, Pardridge WM: Selective expression of the large neutral amino acid transporter at the blood-brain barrier. Proc Natl Acad Sci U S A 1999;96:12079-12084.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12079-12084
    • Boado, R.J.1    Li, J.Y.2    Nagaya, M.3    Zhang, C.4    Pardridge, W.M.5
  • 29
    • 0022369542 scopus 로고
    • Peripheral dopamine synthesis and metabolism in spontaneously hypertensive rats
    • Racz K, Kuchel O, Buu NT, Tenneson S: Peripheral dopamine synthesis and metabolism in spontaneously hypertensive rats. Circ Res 1985;57:889-897.
    • (1985) Circ Res , vol.57 , pp. 889-897
    • Racz, K.1    Kuchel, O.2    Buu, N.T.3    Tenneson, S.4
  • 30
    • 0029083276 scopus 로고
    • Gene expression of aromatic L-amino acid decarboxylase mRNA in the kidney of normotensive and hypertensive rats
    • Sanada H, Watanabe H, Shigetomi S, Fukuchi S: Gene expression of aromatic L-amino acid decarboxylase mRNA in the kidney of normotensive and hypertensive rats. Hypertens Res 1995;18 Suppl 1:S179-181.
    • (1995) Hypertens Res , vol.18 , Issue.SUPPL. 1
    • Sanada, H.1    Watanabe, H.2    Shigetomi, S.3    Fukuchi, S.4
  • 31
    • 0026022773 scopus 로고
    • Role of dopaminergic mechanisms in the kidney for the pathogenesis of hypertension
    • Yoshimura M, Ikegaki I, Nishimura M, Takahashi H: Role of dopaminergic mechanisms in the kidney for the pathogenesis of hypertension. J Auton Pharmacol 1990;10 Suppl 1:s67-72.
    • (1990) J Auton Pharmacol , vol.10 , Issue.SUPPL. 1
    • Yoshimura, M.1    Ikegaki, I.2    Nishimura, M.3    Takahashi, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.