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Vitiligo is a common skin depigmenting disease resulting from the loss of melanocytes in the cutaneous epidermis. The etiology of the disorder remains obscure and curative therapies are not currently available. Several immunosuppressive treatments including corticosteroids and photochemotherapy have been used to induce repigmentation in vitiligo patients but these have given mixed and usually unsustained responses. Surgical techniques including minigrafting, suction blister transplantation, and the transplantation of autologous melanocytes have also been applied to the treatment of vitiligo but not always with satisfactory results. In the article by Czajkowski and colleagues, various surgical modalities in conjunction with photochemotherapy have been compared for the treatment of vitiligo. Most successful appeared to be the use of suction blisters to transplant melanocytes to depigmented lesions plus concurrent treatment with psoralen and ultraviolet A radiation (PUVA).
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