Bacterial expression, NMR, and electrophysiology analysis of chimeric short/long-chain α-neurotoxins acting on neuronal nicotinic receptors

Journal of Biological Chemistry

Volumn 282, Issue 34, 2007, Pages 24784-24791

  Lyukmanova, Ekaterina N ^a   Shenkarev, Zakhar O ^a   Schulga, Alexey A ^a   Ermolyuk, Yaroslav S ^a   Mordvintsev, Dmitry Yu ^a   Utkin, Yurii N ^a   Shoulepko, Mikhail A ^b   Hogg, Ron C ^c   Bertrand, Daniel ^c   Dolgikh, Dmitry A ^a,b   Tsetlin, Victor I ^a   Kirpichnikov, Mikhail P ^a,b  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC TOXINS; DIMERIC ORGANIZATION; NEUROTOXINS; NICOTINIC ACETYLCHOLINE RECEPTORS;

BACTERIA; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; GENE EXPRESSION; MOLECULAR DYNAMICS; MUSCLE; NUCLEAR MAGNETIC RESONANCE;

NEUROLOGY;

ALPHA NEUROTOXIN; KAPPA NEUROTOXIN; NEUROTOXIN; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHIMERA; ELECTROPHYSIOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; GENE MUTATION; MOLECULAR DYNAMICS; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTON NUCLEAR MAGNETIC RESONANCE; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; ELECTROPHYSIOLOGY; ESCHERICHIA COLI; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; NEUROTOXINS; OOCYTES; RECEPTORS, NICOTINIC; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS;

BACTERIA (MICROORGANISMS); NAJA OXIANA;

EID: 34548355080     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611263200     Document Type: Article

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