Unprecedented one-pot stereoselective synthesis of knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents

Synthesis

Volumn , Issue 16, 2007, Pages 2495-2502

  Ranise, Angelo ^a   Cesarini, Sara ^a   Spallarossa, Andrea ^a   Sancassan, Fernando ^a   Bondavalli, Francesco ^a   Bruno, Olga ^a   Schenone, Silvia ^a   Menozzi, Giulia ^a   Fossa, Paola ^a   Mosti, Luisa ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Active methylene reagents; Knoevenagel reaction; Stereoselective synthesis; Ternary iminium salts

Indexed keywords

ACTIVE METHYLENE REAGENTS; KNOEVENAGEL REACTIONS; STEREOSELECTIVE SYNTHESIS; TERNARY IMINIUM SALTS;

AMIDES; BYPRODUCTS; CONDENSATION; HYDROLYSIS; STEREOSELECTIVITY; SYNTHESIS (CHEMICAL);

UREA;

2 IMIDAZOLIDINETHIONE; BENZENECARBONYL CHLORIDE; BENZOIC ACID; CARBENE; CHLORIDE; IMIDAZOLE DERIVATIVE; IMIDAZOLIDINONE; N METHYL N [(2 OXOIMIDAZOLIDIN 1 YL)METHYLENE]METHANAMINIUM CHLORIDE; N METHYL N [(2 THIOXOIMIDAZOLIDIN 1 YL)METHYLENE]METHANAMINIUM CHLORIDE; N,N DIMETHYLFORMAMIDE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; HYDROLYSIS; INFRARED RADIATION; KNOEVENAGEL CONDENSATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 34548349200     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-983811     Document Type: Article

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