Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay

Journal of Animal Science

Volumn 85, Issue 9, 2007, Pages 2330-2336

  Klotz, J L ^a   Bush, L P ^c   Smith, D L ^b   Shafer, W D ^b   Smith, L L ^a   Arlington, B C ^c   Strickland, J R ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b EASTERN KENTUCKY UNIVERSITY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alkaloid; Bovine; Ergotamine; Ergovaline; Fescue; Vasoconstriction

Indexed keywords

ERGOTAMINE; ERGOTAMINE DERIVATIVE; ERGOVALINE; UNCLASSIFIED DRUG; VASOCONSTRICTOR AGENT;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOASSAY; CATTLE; DOSE RESPONSE; DRUG EFFECT; FEMALE; MALE; METHODOLOGY; SAPHENOUS VEIN; VASOCONSTRICTION;

ANIMALS; BIOLOGICAL ASSAY; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOTAMINE; ERGOTAMINES; FEMALE; MALE; SAPHENOUS VEIN; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

ANIMALIA; BOS; BOVINAE; FESTUCA ARUNDINACEA;

EID: 34548327220     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/jas.2006-803     Document Type: Article

References (19)

1. Abney, L. K., J. W. Oliver, and C. R. Reinemeyer. 1993. Vasoconstrictive effects of tall fescue alkaloids on equine vasculature. J. Equine. Vet. Sci. 13:334-340.
2. Berde, B., and E. Strmer. 1978. Introduction to the pharmacology of ergot alkaloids and related compounds as a basis of their therapeutic application. Page 1 in Ergot Alkaloids and Related Compounds. B. Berde and H. O. Schild, ed. Springer-Verlag, Berlin, Germany.
3. Dyer, D. C. 1993. Evidence that ergovaline acts on serotonin receptors. Life Sci. 53:223-228.
4. Hill, N. S., F. N. Thompson, J. A. Stuedemann, G. W. Rottinghaus, H. J. Ju, D. L. Dawe, and E. E. Hiatt III. 2001. Ergot alkaloid transport across ruminant gastric tissues. J. Anim. Sci. 79:542-549.
5. Klotz, J. L., L. P. Bush, D. L. Smith, W. D. Shafer, L. L. Smith, A. C. Vevoda, A. M. Craig, B. C. Arrington, and J. R. Strickland. 2006. Assessment of vasoconstrictive potential of D-lysergic acid using an isolated bovine lateral saphenous vein bioassay. J. Anim. Sci. 84:3167-3175.
6. Lehner, A. F., M. Craig, N. Fannin, L. Bush, and T. Tobin. 2004. Fragmentation patterns of selected ergot alkaloids by electrospray ionization tandem quadrupole mass spectrometry. J. Mass Spectrom. 39:1275-1286.
7. Lyons, P. C., R. D. Plattner, and C. W. Bacon. 1986. Occurrence of peptide and clavinet ergot alkaloids in tall fescue grass. Science 232:487-489.
8. McLeay, L. M., and B. L. Smith. 2006. Effects of ergotamine and ergovaline on the electromyographic activity of smooth muscle of the reticulum and rumen of sheep. Am. J. Vet. Res. 67:707-714.
9. McLeay, L. M., B. L. Smith, and G. W. Reynolds. 2002. Cardiovascular, respiratory, and body temperature responses of sheep to the ergopeptides ergotamine and ergovaline. Am. J. Vet. Res. 63:387-393.
10. Moubarak, A. S., E. L. Piper, C. P. West, and Z. B. Johnson. 1993. Interaction of purified ergovaline from endophyte-infected tall fescue with synaptosomal ATPase enzyme system. J. Agric. Food Chem. 41:407-409.
11. Schöning, C., M. Flieger, and H. H. Pertz. 2001. Complex interaction of ergovaline with 5-HT2A, 5-HT1B/1D, and alphal receptors in isolated arteries of rat and guinea pig. J. Anim. Sci. 79:2202-2209.
12. Schultz, C. L., S. L. Lodge-Ivey, L. P. Bush, A. M. Craig, and J. R. Strickland. 2006. Effects of initial and extended exposure to an endophyte-infected tall fescue seed diet on faecal and urinary excretion of ergovaline and lysergic acid in mature geldings. N. Z. J. Vet. J. 54:178-184.
13. Shappell, N. W. 2003. Ergovaline toxicity on Caco-2 cells as assessed by MTT, alamarBlue, and DNA assays. In Vitro Cell. Dev. Biol. Anim. 39:329-335.
14. Shappell, N. W., and D. J. Smith. 2005. Ergovaline movement across Caco-2 cells. In Vitro Cell. Dev. Biol. Anim. 41:245-251.
15. Smith, D. J., and N. W. Shappell. 2002. Technical note: Epimerization of ergopeptine alkaloids in organic and aqueous solvents. J. Anim. Sci. 80:1616-1622.
16. Solomons, R. N., J. W. Oliver, and R. D. Linnabary. 1989. Reactivity of the dorsal pedal vein of cattle to selected alkaloids associated with Acremonium coenophialum-iniected fescue grass. Am. J. Vet. Res. 50:235-238.
17. Soreng, R. J., E. E. Terrell, J. Wiersema, and S. J. Darbyshire. 2001. Proposal to conserve the name Schedonorus arundinaceus (Schreb.) Dumort. against Schedonorus arundinaceus Roem. & Schult. (Poaceae: Poeae). Taxon 50:915-917.
18. Strickland, J. R., E. M. Bailey, L. K. Abney, and J. W. Oliver. 1996. Assessment of the mitogenic potential of the alkaloids produced by endophyte (Acremonium coenophialum)-infected tall fescue (Festuca arundinacea) on bovine vascular smooth muscle in vitro. J. Anim. Sci. 74:1664-1671.
19. Yates, S. G., R. D. Plattner, and G. B. Garner. 1985. Detection of ergopeptine alkaloids in endophyte-infected, toxic KY-31 tall fescue by mass spectrometry/mass spectrometry. J. Agric. Food Chem. 33:719-722.