Mid-pregnancy maternal plasma levels of interleukin 2, 6, and 12, tumor necrosis factor-alpha, interferon-gamma, and granulocyte-macrophage colony-stimulating factor and spontaneous preterm delivery

Acta Obstetricia et Gynecologica Scandinavica

Volumn 86, Issue 9, 2007, Pages 1103-1110

  Curry, Allison E ^a,b   Vogel, Ida ^b,c   Drews, Carolyn ^a   Schendel, Diana ^d   Skogstrand, Kristin ^b,e   Flanders, W Dana ^a   Hougaard, David ^e   Olsen, Jørn ^b   Thorsen, Poul ^b  

^a EMORY UNIVERSITY   (United States)

^b AARHUS UNIVERSITY   (Denmark)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^e STATENS SERUM INSTITUT   (Denmark)

Author keywords

Biomarkers; Inflammation; Prediction; Premature; Preterm birth

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; AUTHOR; BODY MASS; CASE CONTROL STUDY; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONFOUNDING VARIABLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GESTATIONAL AGE; HUMAN; MATERNAL AGE; PREDICTION; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK;

ADULT; BIOLOGICAL MARKERS; BODY MASS INDEX; CASE-CONTROL STUDIES; COHORT STUDIES; CONFIDENCE INTERVALS; DENMARK; FEMALE; FLOW CYTOMETRY; GESTATIONAL AGE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-2; INTERLEUKIN-6; OBSTETRIC LABOR, PREMATURE; ODDS RATIO; PARITY; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548317277     PISSN: 00016349     EISSN: 16000412     Source Type: Journal    
DOI: 10.1080/00016340701515423     Document Type: Article

References (23)

1. Goldenberg RL, Andrews WW, Hauth JC. Choriodecidual infection and preterm birth. Nutr Rev. 2002;60:S19-25.
2. Greig PC, Murtha AP, Jimmerson CJ, Herbert WN, Roitman-Johnson B, Allen J. Maternal serum interleukin-6 during pregnancy and during term and preterm labor. Obstet Gynecol. 1997;90:465-9.
3. Hillier SL, Witkin SS, Krohn MA, Watts DH, Kiviat NB, Eschenbach DA. The relationship of amniotic fluid cytokines and preterm delivery, amniotic fluid infection, histologic chorioamnionitis, and chorioamnion infection. Obstet Gynecol. 1993;81:941-8.
4. Jun JK, Yoon BH, Romero R, Kim M, Moon JB, Ki SH, et al. Interleukin 6 determinations in cervical fluid have diagnostic and prognostic value in preterm premature rupture of membranes. Am J Obstet Gynecol. 2000;183:868-73.
5. Bahar AM, Ghalib HW, Moosa RA, Zaki ZM, Thomas C, Nabri OA. Maternal serum interleukin-6, interleukin-8, tumor necrosis factor-alpha and interferon-gamma in preterm labor. Acta Obstet Gynecol Scand. 2003;82:543-9.
6. Romero R, Gomez R, Chaiworapongsa T, Conoscenti G, Kim JC, Kim YM. The role of infection in preterm labour and delivery. Paediatr Perinat Epidemiol. 2001;15(Suppl 2):41-56.
7. Wenstrom KD, Andrews WW, Hauth JC, Goldenberg RL, DuBard MB, Cliver SP. Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery. Am J Obstet Gynecol. 1998;178:546-50.
8. Ghidini A, Jenkins CB, Spong CY, Pezzullo JC, Salafia CM, Eglinton GS. Elevated amniotic fluid interleukin-6 levels during the early second trimester are associated with greater risk of subsequent preterm delivery. Am J Reprod Immunol. 1997;37:227-31.
9. Goepfert AR, Goldenberg RL, Andrews WW, Hauth JC, Mercer B, Iams J, et al. The Preterm Prediction Study: association between cervical interleukin 6 concentration and spontaneous preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol. 2001;184:483-8.
10. Goldenberg RL, Iams JD, Mercer BM, Meis PJ, Moawad A, Das A, et al. The Preterm Prediction Study: toward a multiple-marker test for spontaneous preterm birth. Am J Obstet Gynecol. 2001;185:643-51.
11. Olsen J, Melbye M, Olsen SF, Sorensen TI, Aaby P, Andersen AM, et al. The Danish National Birth Cohort - its background, structure and aim. Scand J Public Health. 2001;29:300-7.
12. Thorsen P, Schendel DE, Deshpande AD, Vogel I, Dudley DJ, Olsen J. Identification of biological/biochemical marker(s) for preterm delivery. Paediatr Perinat Epidemiol. 2001;15(Suppl 2):90-103.
13. Skogstrand K, Thorsen P, Norgaard-Pedersen B, Schendel DE, Sorensen LC, Hougaard DM. Simultaneous measurement of 25 inflammatory markers and neurotrophins in neonatal dried blood spots by immunoassay with xMAP technology. Clin Chem. 2005;51:1854-66.
14. National Heart, Lung, and Blood Institute. Clinical guidelines of the identification, evaluation, and treatment of overweight and obesity in adults. NIH Publication No. 98-4083. Department of Health and Human Services, National Institutes of Health, 1998.
15. Flower L, Ahuja RH, Humphries SE, Mohamed-Ali V. Effects of sample handling on the stability of interleukin 6, tumour necrosis factor-alpha and leptin. Cytokine. 2000;12:1712-6.
16. Thavasu PW, Longhurst S, Joel SP, Slevin ML, Balkwill FR. Measuring cytokine levels in blood. Importance of anticoagulants, processing, and storage conditions. J Immunol Methods. 1992;153:115-24.
17. Kenis G, Teunissen C, De Jongh R, Bosmans E, Steinbusch H, Maes M. Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and CC16 in human serum. Cytokine. 2002;19:228-35.
18. Andrews WW, Hauth JC, Cliver SP, Conners M, Goldenberg RL. Endometrial microbial colonization and plasma cell endometritis are common three months postpartum [abstract]. Am J Obstet Gynecol. 2000;182:S53.
19. Korn AP, Bolan G, Padian N, Ohm-Smith M, Schachter J, Landers DV. Plasma cell endometritis in women with symptomatic bacterial vaginosis. Obstet Gynecol. 1995;85:387-90.
20. Cassell GH, Davis RO, Waites KB, Brown MB, Marriott PA, Stagno S, et al. Isolation of Mycoplasma hominis and Ureaplasma urealyticum from amniotic fluid at 16-20 weeks of gestation: potential effect on outcome of pregnancy. Sex Transm Dis. 1983;10:294-302.
21. Horowitz S, Mazor M, Romero R, Horowitz J, Glezerman M. Infection of the amniotic cavity with Ureaplasma urealyticum in the midtrimester of pregnancy. J Reprod Med. 1995;40:375-9.
22. Meis PJ. 17 hydroxyprogesterone for the prevention of preterm delivery. Obstet Gynecol. 2005;105:1128-35.
23. Goldenberg RL, Rouse DJ. Prevention of premature birth. N Engl J Med. 1998;339:313-20.