-
1
-
-
0022001402
-
Strategies in the design of solution-stable, water-soluble prodrugs II: Properties of micellar prodrugs of methylprednisolone
-
Anderson, B. D., Conradi, R. A., Knuth, K. E., & Nail, S. L. (1985). Strategies in the design of solution-stable, water-soluble prodrugs II: Properties of micellar prodrugs of methylprednisolone. J. Pharm. Sci., 74(4), 375-381.
-
(1985)
J. Pharm. Sci
, vol.74
, Issue.4
, pp. 375-381
-
-
Anderson, B.D.1
Conradi, R.A.2
Knuth, K.E.3
Nail, S.L.4
-
2
-
-
0019475132
-
Initial rate studies of hydrolysis and acyl migration in methylprednisolone 21-hemisuccinate and 17-hemisuccinate
-
Anderson, B. D., & Taphouse, V. (1981). Initial rate studies of hydrolysis and acyl migration in methylprednisolone 21-hemisuccinate and 17-hemisuccinate. J. Pharm. Sci., 70(2), 181-186.
-
(1981)
J. Pharm. Sci
, vol.70
, Issue.2
, pp. 181-186
-
-
Anderson, B.D.1
Taphouse, V.2
-
3
-
-
33748293143
-
Etiopathogenesis of inflammatory bowel diseases
-
Danese, S., & Fiocchi C. (2006). Etiopathogenesis of inflammatory bowel diseases. World J. Gastroenterol., 12(30), 4807-4812.
-
(2006)
World J. Gastroenterol
, vol.12
, Issue.30
, pp. 4807-4812
-
-
Danese, S.1
Fiocchi, C.2
-
4
-
-
0036764375
-
Inflammatory bowel disease. Current concepts of pathogenesis and implications for therapy
-
Fiocchi, C. (2002). Inflammatory bowel disease. Current concepts of pathogenesis and implications for therapy. Minerva Gastroenterol. E Dietol., 48(3), 215-226.
-
(2002)
Minerva Gastroenterol. E Dietol
, vol.48
, Issue.3
, pp. 215-226
-
-
Fiocchi, C.1
-
5
-
-
0142156581
-
Standard treatment of ulcerative colitis
-
Gionchetti, P., Rizzello, F., Habal, F., Morselli, C., Amadini, C., Romagnoli, R., & Campieri, M. (2003). Standard treatment of ulcerative colitis. Dig. Dis., 21(3), 157-167.
-
(2003)
Dig. Dis
, vol.21
, Issue.3
, pp. 157-167
-
-
Gionchetti, P.1
Rizzello, F.2
Habal, F.3
Morselli, C.4
Amadini, C.5
Romagnoli, R.6
Campieri, M.7
-
6
-
-
18544408493
-
Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: A new therapeutic strategy
-
Kawanami, C., Oshima, C., Ikada, Y., & Chiba, T. (2000). Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: a new therapeutic strategy. J. Pharmacol. Exp. Ther., 292(1), 15-21.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.292
, Issue.1
, pp. 15-21
-
-
Kawanami, C.1
Oshima, C.2
Ikada, Y.3
Chiba, T.4
-
7
-
-
0021806456
-
Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid
-
Klotz, U. (1985). Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid. Clin. Pharmacokinet., 10(4), 285-302.
-
(1985)
Clin. Pharmacokinet
, vol.10
, Issue.4
, pp. 285-302
-
-
Klotz, U.1
-
8
-
-
25144467678
-
Microparticle targeting to the inflamed colonic mucosa for the treatment of inflammatory bowel disease: In vivo results from rat
-
Abstract 1930
-
Lamprecht, A., Schafer, U., & Lehr, C. M. (2000). Microparticle targeting to the inflamed colonic mucosa for the treatment of inflammatory bowel disease: in vivo results from rat. AAPS Pham. Sci., 2(S1), Abstract 1930.
-
(2000)
AAPS Pham. Sci
, vol.2
, Issue.S1
-
-
Lamprecht, A.1
Schafer, U.2
Lehr, C.M.3
-
9
-
-
0034872426
-
Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa
-
Lamprecht, A., Schafer, U., & Lehr, C. M. (2001c). Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res., 18(6), 788-793.
-
(2001)
Pharm Res
, vol.18
, Issue.6
, pp. 788-793
-
-
Lamprecht, A.1
Schafer, U.2
Lehr, C.M.3
-
10
-
-
0035962390
-
Design of rolipram-loaded nanoparticles: Comparison of two preparation methods
-
Lamprecht, A., Ubrich, N., Yamamoto, H., Schafer, U., Takeuchi, H., Lehr, C. M., Maincent, P., & Kawashima, Y. (2001b). Design of rolipram-loaded nanoparticles: comparison of two preparation methods. J. Control. Release, 71, 297-306.
-
(2001)
J. Control. Release
, vol.71
, pp. 297-306
-
-
Lamprecht, A.1
Ubrich, N.2
Yamamoto, H.3
Schafer, U.4
Takeuchi, H.5
Lehr, C.M.6
Maincent, P.7
Kawashima, Y.8
-
11
-
-
0034756945
-
Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
-
Lamprecht, A., Ubrich, N., Yamamoto, H., Schafer, U., Takeuchi, H., Maincent, P., Kawashima, Y., & Lehr, C. M. (2001a). Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J. Pharmacol. Exp. Ther., 299(2), 775-781.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.299
, Issue.2
, pp. 775-781
-
-
Lamprecht, A.1
Ubrich, N.2
Yamamoto, H.3
Schafer, U.4
Takeuchi, H.5
Maincent, P.6
Kawashima, Y.7
Lehr, C.M.8
-
12
-
-
0029002573
-
Release of 5-ASA from Pentasa in patients with Crohn's disease of the small intestine
-
Larouche, J., Morais, J., Picard, M., Lambert, C., Spenard, J., Landriault, H., Kennedy, G., & Poitras, P. (1995). Release of 5-ASA from Pentasa in patients with Crohn's disease of the small intestine. Aliment. Pharmacol. Ther., 9(3), 315-320.
-
(1995)
Aliment. Pharmacol. Ther
, vol.9
, Issue.3
, pp. 315-320
-
-
Larouche, J.1
Morais, J.2
Picard, M.3
Lambert, C.4
Spenard, J.5
Landriault, H.6
Kennedy, G.7
Poitras, P.8
-
13
-
-
0027231706
-
Synthesis and chemical stability of glucocorticoid-dextran esters: Potential prodrugs for colon-specific delivery
-
McLeod, A. D., Friend, D. R., & Tozer, T. N. (1993). Synthesis and chemical stability of glucocorticoid-dextran esters: Potential prodrugs for colon-specific delivery. Int. J. Pharm., 92, 105-114.
-
(1993)
Int. J. Pharm
, vol.92
, pp. 105-114
-
-
McLeod, A.D.1
Friend, D.R.2
Tozer, T.N.3
-
14
-
-
0034738844
-
Kinetics of hydrolysis of dextran-methylprednisolone succinate, a macromolecular prodrug of methylprednisolone, in rat blood and liver lysosomes
-
Mehvar, R., Dann, R. O., & Hoganson, D. A. (2000) Kinetics of hydrolysis of dextran-methylprednisolone succinate, a macromolecular prodrug of methylprednisolone, in rat blood and liver lysosomes. J. Control. Release., 68(1), 53-61.
-
(2000)
J. Control. Release
, vol.68
, Issue.1
, pp. 53-61
-
-
Mehvar, R.1
Dann, R.O.2
Hoganson, D.A.3
-
15
-
-
0037133114
-
Colon-specific delivery of prednisolone-appended alpha-cyclodextrin conjugate: Alleviation of systemic side effect after oral administration
-
Nakase, H., Okazaki, K., Tabata, Y., Uose, S., Ohana, M., Uchida, K., Matsushima, Y., Yano, H., Hirayama, F., Kamada, M., Arima, H., & Uekama, K. (2002). Colon-specific delivery of prednisolone-appended alpha-cyclodextrin conjugate: Alleviation of systemic side effect after oral administration. J. Control. Release, 79, 103-112.
-
(2002)
J. Control. Release
, vol.79
, pp. 103-112
-
-
Nakase, H.1
Okazaki, K.2
Tabata, Y.3
Uose, S.4
Ohana, M.5
Uchida, K.6
Matsushima, Y.7
Yano, H.8
Hirayama, F.9
Kamada, M.10
Arima, H.11
Uekama, K.12
-
16
-
-
25144499987
-
Preparation and in vitro evaluation of chitosan microspheres containing prednisolone: Comparison of simple and conjugate microspheres
-
Onishi, H., Oosegi, T., Machida, Y., & McGinity J. W. (2005). Preparation and in vitro evaluation of chitosan microspheres containing prednisolone: comparison of simple and conjugate microspheres. Drug Dev. Ind. Pharm., 31(7), 597-605.
-
(2005)
Drug Dev. Ind. Pharm
, vol.31
, Issue.7
, pp. 597-605
-
-
Onishi, H.1
Oosegi, T.2
Machida, Y.3
McGinity, J.W.4
-
17
-
-
0032969652
-
Mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract
-
Sakuma, S., Sudo, R., Suzuki, N., Kikuchi, H., Akashi, M., & Hayashi, M. (1999). Mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract. Int. J. Pharm., 177, 161-172.
-
(1999)
Int. J. Pharm
, vol.177
, pp. 161-172
-
-
Sakuma, S.1
Sudo, R.2
Suzuki, N.3
Kikuchi, H.4
Akashi, M.5
Hayashi, M.6
-
18
-
-
0034862390
-
Bioadhesive characteristics of chitosan microspheres to the mucosa of rat small intestine
-
Shimoda, J., Onishi, H., & Machida, Y. (2001). Bioadhesive characteristics of chitosan microspheres to the mucosa of rat small intestine. Drug Dev. Ind. Pharm., 27(6), 567-576.
-
(2001)
Drug Dev. Ind. Pharm
, vol.27
, Issue.6
, pp. 567-576
-
-
Shimoda, J.1
Onishi, H.2
Machida, Y.3
-
19
-
-
0030470545
-
Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres
-
Tabata, Y., Inoue, Y., & Ikada, Y. (1996). Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres. Vaccine, 14, 1677-1685.
-
(1996)
Vaccine
, vol.14
, pp. 1677-1685
-
-
Tabata, Y.1
Inoue, Y.2
Ikada, Y.3
-
20
-
-
0032937730
-
Colon-specific delivery of budesonide with azopolymer-coated pellets: Therapeutic effects of budesonide with a novel dosage form against 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats
-
Tozaki, H., Fujita, T., Komoike, J., Kim, S. I., Terashima, H., Muranishi, S., Okabe, S., & Yamamoto, A. (1999a). Colon-specific delivery of budesonide with azopolymer-coated pellets: Therapeutic effects of budesonide with a novel dosage form against 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats. J. Pharm. Pharmacol., 51(3), 257-261.
-
(1999)
J. Pharm. Pharmacol
, vol.51
, Issue.3
, pp. 257-261
-
-
Tozaki, H.1
Fujita, T.2
Komoike, J.3
Kim, S.I.4
Terashima, H.5
Muranishi, S.6
Okabe, S.7
Yamamoto, A.8
-
21
-
-
0032710037
-
Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acidi-nduced colitis in rats
-
Tozaki, H., Fujita, T., Odoriba, T., Terabe, A., Okabe, S., Muranishi, S., & Yamamoto, A. (1999b). Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acidi-nduced colitis in rats. J. Pharm. Pharmacol., 51(10), 1107-1112.
-
(1999)
J. Pharm. Pharmacol
, vol.51
, Issue.10
, pp. 1107-1112
-
-
Tozaki, H.1
Fujita, T.2
Odoriba, T.3
Terabe, A.4
Okabe, S.5
Muranishi, S.6
Yamamoto, A.7
-
22
-
-
0030612306
-
Chitosan capsules for colon-specific drug delivery: Improvement of insulin absorption from the rat colon
-
Tozaki, H., Komoike, J., Tada, C., Maruyama, T., Terabe, A., Suzuki, T., Yamamoto, A., & Muranishi, S. (1997). Chitosan capsules for colon-specific drug delivery: improvement of insulin absorption from the rat colon. J. Pharm. Sci., 86(9), 1016-1021.
-
(1997)
J. Pharm. Sci
, vol.86
, Issue.9
, pp. 1016-1021
-
-
Tozaki, H.1
Komoike, J.2
Tada, C.3
Maruyama, T.4
Terabe, A.5
Suzuki, T.6
Yamamoto, A.7
Muranishi, S.8
-
23
-
-
0037130218
-
Chitosan capsules for colon-specific drug deliver: Enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats
-
Tozaki, H., Odoriba, T., Okada, N., Fujita, T., Terabe, A., Suzuki, T., Okabe, S., Muranishi, S., & Yamamoto, A. (2002). Chitosan capsules for colon-specific drug deliver: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats. J. Control. Release, 82, 51-61.
-
(2002)
J. Control. Release
, vol.82
, pp. 51-61
-
-
Tozaki, H.1
Odoriba, T.2
Okada, N.3
Fujita, T.4
Terabe, A.5
Suzuki, T.6
Okabe, S.7
Muranishi, S.8
Yamamoto, A.9
-
24
-
-
0034994175
-
In vivo uptake of chitosan microparticles by murine Peyer's patches: Visualization studies using confocal laser scanning microscopy and immunohistochemistry
-
Van Der Lubben, I. M., Konings, F. A., Borchard, G., Verhoef, J. C., & Junginger, H. E. (2001). In vivo uptake of chitosan microparticles by murine Peyer's patches: visualization studies using confocal laser scanning microscopy and immunohistochemistry. J. Drug Target, 9(1), 39-47.
-
(2001)
J. Drug Target
, vol.9
, Issue.1
, pp. 39-47
-
-
Van Der Lubben, I.M.1
Konings, F.A.2
Borchard, G.3
Verhoef, J.C.4
Junginger, H.E.5
-
25
-
-
0026499175
-
The transit rate of different sized model dosage forms through the human colon and the effects of a lactulose-induced catharsis
-
Watts, P. J., Barrow, L., Steed, K. P., Wilson, C. G., Spiller, R. C., Melia, C. D., & Davies, M. C. (1992). The transit rate of different sized model dosage forms through the human colon and the effects of a lactulose-induced catharsis. Int. J. Pharm., 87, 215-221.
-
(1992)
Int. J. Pharm
, vol.87
, pp. 215-221
-
-
Watts, P.J.1
Barrow, L.2
Steed, K.P.3
Wilson, C.G.4
Spiller, R.C.5
Melia, C.D.6
Davies, M.C.7
|