A degradation product of halobetasol propionate-Characterization and structure

Steroids

Volumn 72, Issue 11-12, 2007, Pages 787-791

  Cravotto, Giancarlo ^a   Giovenzana, Giovanni B ^b   Masciocchi, Norberto ^c   Palmisano, Giovanni ^c   Volante, Paolo ^d  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c Dip Scienze Chimiche e Ambientali   (Italy)

^d Poli Industria Chimica SpA   (Italy)

Author keywords

Degradation; Halobetasol propionate; Structure delucidation; Topical corticosteroid

Indexed keywords

CORTICOSTEROID DERIVATIVE; HABETASOL PROPIONATE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

CATALYSIS; CLOBETASOL; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; VASOCONSTRICTOR AGENTS;

EID: 34548297582     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.06.003     Document Type: Article

References (5)

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2. In the treatment of psoriasis, caution must be used when mixing the two agents, as some topical corticosteroids will result in the degradation of the vitamin D analogue.
3. Column: symmetry (4.6 mm × 250 mm, 5 μ); eluant: acetonitrile-water 50/50.
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