Persistent delayed-type hypersensitivity reaction to injectable non-animal-stabilized hyaluronic acid

Journal of Cosmetic Dermatology

Volumn 6, Issue 3, 2007, Pages 167-171

  Arron, Sarah Tuttleton ^a   Neuhaus, Isaac M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Dermatology ^*  (United States)

Author keywords

Filler; Hyaluronic acid; Hypersensitivity

Indexed keywords

AZATHIOPRINE; GLYCOSAMINOGLYCAN; HYALURONIC ACID; HYALURONIDASE; MATRIGEL; METHYLPREDNISOLONE;

ADD ON THERAPY; ADULT; ARTICLE; CASE REPORT; DELAYED HYPERSENSITIVITY; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; EUROPE; FACE EDEMA; FEMALE; FOOD AND DRUG ADMINISTRATION; HUMAN; INJECTION SITE PAIN; INJECTION SITE SWELLING; LOADING DRUG DOSE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SOFT TISSUE DEFECT; STEROID THERAPY; UNITED STATES;

BIOCOMPATIBLE MATERIALS; COSMETIC TECHNIQUES; EDEMA; FACIAL DERMATOSES; FEMALE; HUMANS; HYALURONIC ACID; HYPERSENSITIVITY, DELAYED; INJECTIONS; MIDDLE AGED; SKIN; SKIN AGING;

EID: 34548297052     PISSN: 14732130     EISSN: 14732165     Source Type: Journal    
DOI: 10.1111/j.1473-2165.2007.00331.x     Document Type: Article

References (11)

1. Leonhardt JM, Lawrence N, Narins RS. Angioedema acute hypersensitivity reaction to injectable hyaluronic acid. Dermatol Surg 2005; 31: 577-9.
2. Matarasso SL, Herwick R. Hypersensitivity reaction to nonanimal stabilized hyaluronic acid. J Am Acad Dermatol 2006; 55: 128-31.
3. Duffy DM. Complications of fillers: Overview. Dermatol Surg 2005; 31: 1626-33.
4. Friedman PM, Mafong EA, Kauvar AN, Geronemus RG. Safety data of injectable nonanimal stabilized hyaluronic acid gel for soft tissue augmentation. Dermatol Surg 2002; 28: 491-4.
5. Q-Medical Sweden. Company Report. Protein content in Q-medical aesthetic products (Restylane, Restylane Fine Lines, Perlane); 2001.
6. Andre P. Evaluation of the safety of a non-animal stabilized hyaluronic acid (NASHA-Q-Medical, Sweden) in European countries: A retrospective study from 1997 to 2001. J Eur Acad Dermatol Venereol 2004; 18: 422-5.
7. Lowe NJ, Maxwell CA, Lowe P, Duick MG, Shah K. Hyaluronic acid skin fillers: Adverse reactions and skin testing. J Am Acad Dermatol 2001; 45: 930-3.
8. Andre P, Lowe NJ, Parc A, Clerici TH, Zimmermann U. Adverse reactions to dermal fillers: A review of European experiences. J Cosmet Laser Ther 2005; 7: 171-6.
9. Lupton JR, Alster TS. Cutaneous hypersensitivity reaction to injectable hyaluronic acid gel. Dermatol Surg 2000; 26: 135-7.
10. Micheels P. Human anti-hyaluronic acid antibodies: Is it possible? Dermatol Surg 2001; 27: 185-91.
11. Wohlrab J, Lueftl M, Marsch WC. Persistent erythema and edema of the midthird and upper aspect of the face (morbus morbihan): Evidence of hidden immunologic contact urticaria and impaired lymphatic drainage. J Am Acad Dermatol 2005; 52: 595-602.