Involvement of the Snk-SPAR pathway in glutamate-induced excitotoxicity in cultured hippocampal neurons

Brain Research

Volumn 1168, Issue 1, 2007, Pages 38-45

  Wu, Lan Xiang ^a   Sun, Chang Kai ^a   Zhang, Yu Mei ^a   Fan, Ming ^b   Xu, Jing ^a   Ma, Hui ^a   Zhang, Jian ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Dendritic spine; Glutamate; MK801; Serum induced kinase; Spine associated Rap GTPase activating protein

Indexed keywords

DIZOCILPINE; GLUTAMIC ACID; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POLO LIKE KINASE 2; SPINE ASSOCIATED RAP GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LOSS; CONTROLLED STUDY; DENDRITIC SPINE; ENZYME ACTIVATION; EXCITOTOXICITY; HIPPOCAMPUS; NERVE CELL STIMULATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SYNAPSE;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; DENDRITIC SPINES; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GLUTAMIC ACID; GTPASE-ACTIVATING PROTEINS; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; L-LACTATE DEHYDROGENASE; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; NEURONS; PROTEIN KINASES; RATS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 34548277955     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.06.082     Document Type: Article

References (26)

1. Allison D.W., Chervin A.S., Gelfand V.I., and Craig A.M. Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: maintenance of core components independent of actin filaments and microtubules. J. Neurosci. 20 (2000) 4545-4554
2. Carlisle H.J., and Kennedy M.B. Spine architecture and synaptic plasticity. Trends Neurosci. 28 (2005) 182-187
3. Charych E.I., Akum B.F., Goldberg J.S., Jörnsten R.J., Rongo C., Zheng J.Q., and Firestein B.L. Activity-independent regulation of dendrite patterning by postsynaptic density protein PSD-95. J. Neurosci. 26 (2006) 10164-10176
4. Ehlers M.D. Molecular morphogens for dendritic spines. Trends Neurosci. 25 (2002) 64-67
5. Fiala J.C., Feinberg M., Popov V., and Harris K.M. Synaptogenesis via dendritic filopodia in developing hippocampal area CA1. J. Neurosci. 18 (1998) 8900-8911
6. Fiala J.C., Spacek J., and Harris K.M. Dendritic spine pathology: cause or consequence of neurological disorders?. Brain Res. Brain Res. Rev. 39 (2002) 29-54
7. Fischer M., Kaech S., Wagner U., Brinkhaus H., and Matus A. Glutamate receptors regulate actin-based plasticity in dendritic spines. Nat. Neurosci. 3 (2000) 887-894
8. Grossman A.W., Aldridge G.M., Weiler I.J., and Greenough W.T. Local protein synthesis and spine morphogenesis: fragile X syndrome and beyond. J. Neurosci. 26 (2006) 7151-7155
9. Halpain S., Hipolito A., and Saffer L. Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J. Neurosci. 18 (1998) 9835-9844
10. Harris K.M., and Kater S.B. Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function. Annu. Rev. Neurosci. 17 (1994) 341-371
11. Huang Z.H., Wu H.J., Yeh C.C., Chou Y.C., and Chang Y.C. Dendritic spines of developing rat cortical neurons in culture. Chin. J. Physiol. 49 (2006) 39-45
12. 2+- and integrin-binding protein and are regulated dynamically with synaptic plasticity. EMBO J. 18 (1999) 5528-5539
13. Marin-Padilla M. Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study. Brain Res. 44 (1972) 625-629
14. Matus A. Actin-based plasticity in dendritic spines. Science 290 (2000) 754-758
15. Matus A., Brinkhaus H., and Wagner U. Actin dynamics in dendritic spines: a form of regulated plasticity at excitatory synapses. Hippocampus 10 (2000) 555-560
16. Meyer G., and Brose N. Neuroscience. SPARring with spines. Science 302 (2003) 1341-1344
17. Pak D.T., and Sheng M. Targeted protein degradation and synapse remodeling by an inducible protein kinase. Science 302 (2003) 1368-1373
18. Pak D.T., Yang S., Rudolph-Correia S., Kim E., and Sheng M. Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP. Neuron 31 (2001) 289-303
19. Parnass Z., Tashiro A., and Yuste R. Analysis of spine morphological plasticity in developing hippocampal pyramidal neurons. Hippocampus 10 (2000) 561-568
20. Purpura D.P. Dendritic spine "dysgenesis" and mental retardation. Science 186 (1974) 1126-1128
21. Schubert V., and Dotti C.G. Transmitting on actin: synaptic control of dendritic architecture. J. Cell Sci. 120 (2007) 205-212
22. Seeburg D.P., Pak D., and Sheng M. Polo-like kinases in the nervous system. Oncogene 24 (2005) 292-298
23. Segal M. New building blocks for the dendritic spine. Neuron 31 (2001) 169-171
24. 2+/calmodulin-dependent protein kinase II-mediated actin reorganization. J. Neurosci. 26 (2006) 1813-1822
25. Spires T.L., Molnar Z., Kind P.C., Cordery P.M., Upton A.L., Blakemore C., and Hannan A.J. Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-(1 signalling). Cereb. Cortex 15 (2005) 385-393
26. Wang B.L., and Larsson L.I. Simultaneous demonstration of multiple antigens by indirect immunofluorescence or immunogold staining. Novel light and electron microscopical double and triple staining method employing primary antibodies from the same species. Histochemistry 83 (1985) 47-56