Thermodynamic analysis of additivity between the heavy and light chains in affinity maturation of an antibody

Molecular Immunology

Volumn 45, Issue 1, 2008, Pages 304-305

  Kang, Jonghoon ^a   Warren, Andrew S ^a  

^a VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

Author keywords

Additivity; Affinity maturation; Antigen antibody interaction; Cooperativity; Enthalpy entropy compensation; Thermodynamics

Indexed keywords

ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY REACTION; CALORIMETRY; CELL MATURATION; ENTHALPY; ENTROPY; HEAVY CHAIN; HUMAN; LETTER; LIGHT CHAIN; POINT MUTATION; PRIORITY JOURNAL; THERMODYNAMICS;

ANTIBODY AFFINITY; ANTIGEN-ANTIBODY REACTIONS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; THERMODYNAMICS;

EID: 34548270519     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.07.007     Document Type: Letter

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