TP53 gene polymorphisms and colorectal cancer risk in Chinese population

National Medical Journal of China

Volumn 87, Issue 21, 2007, Pages 1448-1451

  Jia, Hang Ruo ^a   He, Xiang Lei ^b   Zhu, Zhong Zheng ^b   Jin, Xia Xiang ^b   Wang, Ai Zhong ^b   Huang, Hai Yan ^b   Zhu, Jiong ^b   Yu, Guo Bing ^b   Zhu, Guan Shan ^b  

^a No 113 Hospital of People's Liberation Army   (China)

^b NONE

Author keywords

Colorectal neoplasms; Gene, TP53; Genetic predisposition to disease

Indexed keywords

DNA; PROTEIN P53;

ADULT; AGE DISTRIBUTION; AGED; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; BLOOD SAMPLING; BODY MASS; CALCULATION; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CIGARETTE SMOKING; COLORECTAL CANCER; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA EXTRACTION; DOSE RESPONSE; FAMILY HISTORY; FEMALE; GENDER; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; LEUKOCYTE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COLORECTAL NEOPLASMS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMOKING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34548259372     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Gomez-Lazaro M, Fernandez-Gomez FJ, Jordan J. p53: twenty five years understanding the mechanism of genome protection. J Physiol Biochem, 2004, 60: 287-307.
2. Iacopetta B. TP53 mutation in colorectal cancer. Hum Mutat, 2003, 21: 271-276.
3. Baker SJ, Fearon ER, Nigro JM, et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science, 1989, 244: 217-221.
4. Soong R, Powell B, Elsaleh H, et al Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation. Eur J Cancer, 2000, 36: 2053-2060.
5. Almen DJ, Feigl P, Quan G, et al. Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: a Southwest Oncology Group study. Cancer Res, 1998, 58: 1149-1158.
6. Elsaleh H, Powell B, McCaul K, et al. p53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin Cancer Res, 2001, 7: 1343-1349.
7. Liang JT, Huang KC, Cheng YM, et al. P53 overexpression predicts poor chemosensitivity to high-dose 5-fluorouracil plus leueovorin chemotherapy for stage TV colorectal cancers after palliative bowel resection. Int J Cancer, 2002, 97: 451-457.
8. Chinese source.
9. Zhu ZZ, Cong WM, Liu SF, et al. A p53 polymorphism modifies the risk of hepatocellular carcinoma among non-carriers but not carriers of chronic hepatitis B virus infection. Cancer Lett, 2005, 229: 77-83.
10. Lee JM, Lee YC, Yang SY, et al. Genetic polymorphisms of p53 and GSTP1, but not NAT2, are associated with susceptibility to squamous-cell carcinoma of the esophagus. Int J Cancer, 2000, 89: 458-464.
11. Chinese source.
12. Chinese source.
13. Kawajiri K, Nakachi K, Imai K, et al. Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer. Carcinogenesis, 1993, 14: 1085-1089.
14. Gemignani F, Moreno V, Landi S, et al. A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA. Oncogene, 2004, 23: 1954-1956.
15. Perez LO, Abba MC, Dulout FN, et al. Evaluation of p53 codon 72 polymorphisin in adenocarcinomas of the colon and rectum in La Plata, Argentina. World J Gastroenterol, 2006, 12: 1426-1429.
16. Schneider-Stock R, Boltze C, Peters B, et al. Selective loss of codon 72 proline p53 and frequent mutational inactivation of the retained arginine allele in colorectal cancer. Neoplasia, 2004, 6: 529-535.
17. Boffetta P, Hashibe M. Alcohol and cancer. Lancet Oncol, 2006, 7: 149-156.
18. Hsieh LL, Huang TH, Chen IH, et al. p53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan. Br J Cancer, 2005, 92: 30-35.