Effect of pantoprazole in older patients with erosive esophagitis

Diseases of the Esophagus

Volumn 20, Issue 5, 2007, Pages 411-415

  DeVault, Kenneth R ^a   Morgenstern, D M ^b   Lynn, R B ^b   Metz, D C ^c  

^a MAYO CLINIC   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Elderly; Esophagus; Gastroesophageal reflux; Pantoprazole; Proton pump

Indexed keywords

NIZATIDINE; PANTOPRAZOLE; PLACEBO;

ABDOMINAL PAIN; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; ESOPHAGOSCOPY; FEMALE; GASTROESOPHAGEAL REFLUX; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MEDICAL RECORD; NAUSEA; OUTCOME ASSESSMENT; POST HOC ANALYSIS; PRIORITY JOURNAL; REFLUX ESOPHAGITIS; SYMPTOM; TIME; TREATMENT OUTCOME; WOUND HEALING;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; AGED; ANTI-ULCER AGENTS; DOUBLE-BLIND METHOD; ESOPHAGITIS, PEPTIC; FEMALE; HUMANS; MALE; MIDDLE AGED; NIZATIDINE; TIME FACTORS; TREATMENT OUTCOME; WOUND HEALING;

EID: 34548255404     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2007.00642.x     Document Type: Article

References (24)

1. Heading R C. Epidemiology of esophageal reflux disease. Scand J Gastroenterol Suppl 1989; 168: 33-7.
2. Johnson D A. Gastroesophageal reflux disease in the elderly - a prevalent and severe disease. Rev Gastroenterol Disord 2004; 4: S16-24.
3. Raiha I J, Impivaara O, Seppala M, Sourander L B. Prevalence and characteristics of symptomatic gastroesophageal reflux disease in the elderly. J Am Geriatr Soc 1992; 40: 1209-11.
4. Talley N J, O'Keefe E A, Zinsmeister A R, Melton L J III. Prevalence of gastrointestinal symptoms in the elderly: A population-based study. Gastroenterology 1992; 102: 895-901.
5. Achem S R, DeVault K R. Esophageal disease in older patients. In: The Esophagus. Philadelphia: Lippincott Williams & Wilkins, 2005; 668-93.
6. Locke G R III, Talley N J, Fett S L, Zinsmeister A R, Melton L J III. Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota. Gastroenterol 1997; 112: 1448-56.
7. Collen M J, Abdulian J D, Chen Y K. Gastroesophageal reflux disease in the elderly: More severe disease that requires aggressive therapy. Am J Gastroenterol 1995; 90: 1053-7.
8. Voutilainen M, Sipponen P, Mecklin J P, Juhola M, Farkkila M. Gastroesophageal reflux disease: Prevalence, clinical, endoscopic and histopathological findings in 1128 consecutive patients referred for endoscopy due to dyspeptic and reflux symptoms. Digestion 2000; 61: 6-13.
9. Katz P O. Gastroesophageal reflux disease. J Am Geriatr Soc 1998; 46: 1558-65.
10. Achem A C, Achem S R, Stark M E, DeVault K R. Failure of esophageal peristalsis in older patients: Association with esophageal acid exposure. Am J Gastroenterol 2003; 98: 35-9.
11. Hollis J B, Castell D O. Esophageal function in elderly man. A new look at 'presbyesophagus'. Ann Intern Med 1974; 80: 371-4.
12. Grande L, Lacima G, Ros E et al. Deterioration of esophageal motility with age: A manometric study of 79 healthy subjects. Am J Gastroenterol 1999; 94: 1795-801.
13. Ferriolli E, Oliveira R B, Matsuda N M, Braga F J, Dantas R O. Aging, esophageal motility, and gastroesophageal reflux. J Am Geriatr Soc 1998; 46: 1534-7.
14. Richter J E, Bochenek W. Oral pantoprazole for erosive esophagitis: A placebo-controlled, randomized clinical trial. Pantoprazole US GERD Study Group. Am J Gastroenterol 2000; 95: 3071-80.
15. Kovacs T O, Wilcox C M, DeVault K, Miska D, Bochenek W. Comparison of the efficacy of pantoprazole vs. nizatidine in the treatment of erosive esophagitis: A randomized, active-controlled, double-blind study. Aliment Pharmacol Ther 2002; 16: 2043-52.
16. Pilotto A, Leandro G, Franceschi M. Short- and long-term therapy for reflux esophagitis in the elderly: A multi-centre, placebo-controlled study with pantoprazole. Aliment Pharmacol Ther 2003; 17: 1399-406.
17. Gillessen A, Beil W, Modlin I M, Gatz G, Hole U. 40 mg pantoprazole and 40 mg esomeprazole are equivalent in the healing of esophageal lesions and relief from gastroesophageal reflux disease-related symptoms. J Clin Gastroenterol 2004; 38: 332-40.
18. Hetzel D J, Dent J, Reed W D et al. Healing and relapse of severe peptic esophagitis after treatment with omeprazole. Gastroenterology 1988; 95: 903-12.
19. Triadafilopoulos G, Sharma R. Features of symptomatic gastroesophageal reflux disease in elderly patients. Am J Gastroenterol 1997; 92: 2007-11.
20. El-Serag H B, Sonnenberg A. Associations between different forms of gastro-esophageal reflux disease. Gut 1997; 41: 594-9.
21. Garnett W R, Garabedian-Ruffalo S M. Identification, diagnosis, and treatment of acid-related diseases in the elderly: Implications for long-term care. Pharmacotherapy 1997; 17: 938-58.
22. Skoutakis V A, Joe R H, Hara D S. Comparative role of omeprazole in the treatment of gastroesophageal reflux disease. Ann Pharmacother 1995; 29: 1252-62.
23. James O F, Parry-Billings K S. Comparison of omeprazole and histamine H2-receptor antagonists in the treatment of elderly and young patients with reflux oesophagitis. Age Ageing 1994; 23: 121-6.
24. McTavish D, Buckley M M, Heel R C. Omeprazole. An updated review of its pharmacology and therapeutic use in acid-related disorders. Drugs 1991; 42: 138-170.