Effect of lymph node micrometastases on prognosis of gastric carcinoma

World Journal of Gastroenterology

Volumn 13, Issue 30, 2007, Pages 4122-4125

  Wu, Ze Yu ^a   Li, Jing Hua ^b   Zhan, Wen Hua ^c   He, Yu Long ^c   Wan, Jin ^a  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Gastric carcinoma; Lymph node micrometastases; Prognosis; Stage

Indexed keywords

CYTOKERATIN 20;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; DIAGNOSTIC VALUE; DISEASE SEVERITY; FEMALE; FOLLOW UP; GASTRECTOMY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KAPLAN MEIER METHOD; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MALE; MICROMETASTASIS; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; STAINING; STATISTICAL SIGNIFICANCE; STOMACH CARCINOMA; SURVIVAL RATE; SURVIVAL TIME; TUMOR CLASSIFICATION;

EID: 34548249033     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v13.i30.4122     Document Type: Article

References (28)

1. Saito H, Fukumoto Y, Osaki T, Fukuda K, Tatebe S, Tsujitani S, Ikeguchi M. Prognostic significance of level and number of lymph node metastases; in patients with gastric cancer. Ann Surg Oncol 2007; 14: 1688-1693
2. Barbour AP, Rizk NP, Gonen M, Tang L, Bains MS, Rusch VW, Coit DG, Brennan MF. Lymphadenectomy for adenocarcinoma of the gastroesophageal junction (GEJ): impact of adequate staging on outcome. Ann Surg Oncol 2007; 14:306-316
3. Al-Moundhri MS, Al-Bahrani B, Burney IA, Nirmala V, Al-Madhani A, Al-Mawaly K, Al-Nabhani M, Thomas V, Ganguly SS, Grant CS. The prognostic determinants of gastric cancer treatment outcome in Omani Arab patients. Oncology 2006; 70: 90-96
4. Otsuji E, Kuriu Y, Ichikawa D, Okamoto K, Hagiwara A, Yamagishi H. Tumor recurrence and its timing following curative resection of early gastric carcinoma. Anticancer Res 2003; 23: 3499-3503
5. Hoksch B, Muller JM. Surgical management of locoregional recurrence of gastric carcinoma. Zentralbl Chir 1999; 124: 1087-1090
6. Ohgaki M, Toshio T, Akeo H, Yamasaki J, Togawa T. Effect of extensive lymph node dissection on the survival of early gastric cancer. Hepatogastroenterology 1999; 46: 2096-2099
7. Harrison LE, Choe JK, Goldstein M, Meridian A, Kim SH, Clarke K. Prognostic significance of immunohistochemical micrometastases in node negative gastric cancer patients. J Surg Oncol 2000; 73: 153-157
8. Lee E, Chae Y, Kim I, Choi J, Yeom B, Leong AS. Prognostic relevance of immunohistochemically detected lymph node micrometastasis in patients with gastric carcinoma. Cancer 2002; 94: 2867-2873
9. Yasuda K, Adachi Y, Shiraishi N, Inomata M, Takeuchi H, Kitano S. Prognostic effect of lymph node micrometastasis in patients with histologically node-negative gastric cancer. Ann Surg Oncol 2002; 9: 771-774
10. Ajisaka H, Miwa K. Micrometastases in sentinel nodes of gastric cancer. Br J Cancer 2003; 89: 676-680
11. Higashi H, Natsugoe S, Ishigami S, Uenosono Y, Matsumoto M, Nakajo A, Miyazono F, Hokita S, Takao S, Aikou T. Distribution of lymph node metastasis including micrometastasis in gastric cancer with submucosal invasion. World J Surg 2003; 27: 455-459
12. Karube T, Ochiai T, Shimada H, Nikaidou T, Hayashi H. Detection of sentinel lymph nodes in gastric cancers based on immunohistochemidcal analysis of micrometastases. J Surg Oncol 2004; 87:32-38
13. Okada Y, Fujiwara Y, Yamamoto H, Sugita Y, Yasuda T, Doki Y, Tamura S, Yano M, Shiozaki H, Matsuura N, Monden M. Genetic detection of lymph node micrometastases in patients with gastric carcinoma by multiple-marker reverse transcriptase-polymerase chain reaction assay. Cancer 2001; 92: 2056-2064
14. Wu ZY, Li JH, Zhan WH, He YL. Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma. World J Gastroenterol 2066; 12: 2941-2944
15. Orsenigo E, Tomajer V, Palo SD, Carlucci M, Vignali A, Tamburini A, Staudacher C. Impact of age on postoperative outcomes in 1118 gastric cancer patients undergoing surgical treatment. Gastric Cancer 2007; 10: 39-44
16. Toneri M, Mitsumoto Y, Shimabukuro M, Sunagawa T, Itagaki T, Iida S, Kondo T, Matsuura K, Okeda J, Dhar DK. Prognosis of patients with gastric carcinoma treated in remote island hospitals in Japan: a multivariable analysis. Anticancer Res 2006; 26: 3621-3625
17. Vasilescu C, Herlea V, Tidor S, Ivanov B, Stanciulea. O, Manuc M, Gheorghe C, Ionescu M, Diculescu M, Popescu 1. D2 lymph node dissection in gastric cancer surgery: long term results-analysis of an experience with 227 patients. Chirurgia (Bucur) 2006; 101: 375-384
18. Kim DY, Seo KW, Joo JK, Park YK, Ryu SY, Kim HR, Kim YJ, Kim SK. Prognostic factors in patients with node-negative gastric carcinoma: a comparison with node-positive gastric carcinoma. World J Gastroenterol 2006; 12: 1182-1186
19. Kunisaki C, Akiyama H, Nomura M, Matsuda G, Otsuka Y, Ono HA, Nagahori Y, Takahashi M, Kito F, Shimada H. Surgical outcomes in patients with T4 gastric carcinoma. J Am Coll Surg 2006; 202: 223-230
20. Hundahl SA, Phillips JL, Menck HR. The National Cancer Data Base Report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer staging, proximal disease, and the "different disease" hypothesis. Cancer 2000; 88: 921-932
21. Kodera Y, Yamamura Y, Shimizu Y, Torii A, Hirai T, Yasui K, Morimoto T, Kato T, Kito T. The number of metastatic lymph nodes: a promising prognostic determinant for gastric carcinoma in the latest edition of the TNM classification. J Am Coll Surg 1998; 187: 597-603
22. Matsumoto M, Natsugoe S, Ishigami S, Nakashima S, Nakajo A, Miyazono F, Hokita S, Takao S, Eizuru Y, Aikou T. Lymph node micrometastasis and lymphatic mapping determined by reverse transcriptase-polymerase chain reaction in pNO gastric carcinoma. Surgery 2002; 131: 630-635
23. Ishida K, Katsuyama T, Sugiyama A, Kawasaki S. Immunohistochemical evaluation of lymph node micrometastases from gastric carcinomas. Cancer 1997; 79: 1069-1076
24. Cai J, Ikeguchi M, Maeta M, Kaibara N, Sakatani T. Clinicopathological value of inummohistochemical detection of occult involvement in pT3NO gastric cancer. Gastric Cancer 1999; 2: 95-100
25. Cai J, Ikeguchi M, Tsujitani S, Maeta M, Kaibara N. Micrometastasis in lymph nodes of mucosal gastric cancer. Gastric Cancer 2000; 3: 91-96
26. Ikeguchi M, Cai J, Oka S, Gomyou Y, Tsujitani S, Maeta M, Kaibara N. Nuclear profiles of cancer cells reveal the metastatic potential of gastric cancer. J Pathol 2000; 192: 19-25
27. Okada Y, Fujiwara Y, Yamamoto H, Sugita Y, Yasuda T, Doki Y, Tamura S, Yano M, Shiozaki H, Matsuura N, Monden M. Genetic detection of lymph node micrometastases in patients with gastric carcinoma by multiple-marker reverse transcriptase-polymerase chain reaction assay. Cancer 2001; 92: 2056-2064
28. Fukagawa T, Sasako M, Mann GB, Sano T, Katai H, Maruyama K, Nakanishi Y, Shimoda T. Immunohistochemically detected micrometastases of the lymph nodes in patients with gastric carcinoma. Cancer 2001; 92: 753-760