Differentiation of adrenal adenoma and nonadenoma in unenhanced CT: New optimal threshold value and the usefulness of size criteria for differentiation

Korean Journal of Radiology

Volumn 8, Issue 4, 2007, Pages 328-335

  Sung, Hee Park ^a   Kim, Myeong Jin ^a,b   Joo, Hee Kim ^a   Joon, Seok Lim ^a   Ki, Whang Kim ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Adrenal gland; CT adrenal gland; Neoplasms

Indexed keywords

ADENOMA; ADOLESCENT; ADRENAL TUMOR; ADRENALECTOMY; ADULT; AGED; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; LYMPHOMA; MALE; MIDDLE AGED; PHEOCHROMOCYTOMA; PREDICTION AND FORECASTING; RADIOGRAPHY; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

ADENOMA; ADOLESCENT; ADRENAL GLAND NEOPLASMS; ADRENALECTOMY; ADULT; AGED; FEMALE; HUMANS; LYMPHOMA; MALE; MIDDLE AGED; PHEOCHROMOCYTOMA; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 34548247637     PISSN: 12296929     EISSN: None     Source Type: Journal    
DOI: 10.3348/kjr.2007.8.4.328     Document Type: Article

References (36)

1. Kloos RT, Gross MD, Francis IR, Korobkin M, Shapiro B. Incidentally discovered adrenal masses. Endocr Rev 1995;16:460-484
2. Caplan RH, Strutt PJ, Wickus GG. Subclinical hormone secretion by incidentally discovered adrenal masses. Arch Surg 1994;129:291-296
3. Herrera MF, Grant CS, van Heerden JA, Sheedy PF, Ilstrup DM. Incidentally discovered adrenal tumors: an institutional perspective. Surgery 1991;110:1014-1021
4. Kokko JP, Brown TC, Berman MM. Adrenal adenoma and hypertension. Lancet 1967;1:468-470
5. Dobbie JW. Adrenocortical nodular hyperplasia: the ageing adrenal. J Pathol 1969;99:1-18
6. Abecassis M, McLoughlin MJ, Langer B, Kudlow JE. Serendipitous adrenal masses: prevalence, significance, and management. Am J Surg 1985;149:783-788
7. Oliver TW, Bernardino ME, Miller JI, Mansour K, Greene D, Davis WA. Isolated adrenal masses in nonsmall-cell bronchogenic carcinoma. Radiology 1984;153:217-218
8. Welch TJ, Sheedy PF, 2nd, Stephens DH, Johnson CM, Swensen SJ. Percutaneous adrenal biopsy: review of a 10-year experience. Radiology 1994;193:341-344
9. Heaston DK, Handel DB, Ashton PR, Korobkin M. Narrow gauge needle aspiration of solid adrenal masses. AJR Am J Roentgenol 1982;138:1143-1148
10. Tang CK, Gray GF. Adrenocortical neoplasms. Prognosis and morphology. Urology 1975;5:691-695
11. Bernardino ME, Walther MM, Phillips VM, Graham SD Jr, Sewell CW, Gedgaudas-McClees K, et al. CT-guided adrenal biopsy: accuracy, safety, and indications. AJR Am J Roentgenol 1985;144:67-69
12. Korobkin M, Brodeur FJ, Yutzy GG, Francis IR, Quint LE, Dunnick NR, et al. Differentiation of adrenal adenomas from nonadenomas using CT attenuation values. AJR Am J Roentgenol 1996;166:531-536
13. Glazer HS, Weyman PJ, Sagel SS, Levitt RG, McClennan BL. Nonfunctioning adrenal masses: incidental discovery on computed tomography. AJR Am J Roentgenol 1982;139:81-85
14. Miyake H, Maeda H, Tashiro M, Suzuki K, Nagatomo H, Aikawa H, et al. CT of adrenal tumors: frequency and clinical significance of low-attenuation lesions. AJR Am J Roentgenol 1989;152:1005-1007
15. Lee MJ, Hahn PF, Papanicolaou N, Egglin TK, Saini S, Mueller PR, et al. Benign and malignant adrenal masses: CT distinction with attenuation coefficients, size, and observer analysis. Radiology 1991;179:415-418
16. van Erkel AR, van Gils AP, Lequin M, Kruitwagen C, Bloem JL, Falke TH. CT and MR distinction of adenomas and nonadenomas of the adrenal gland. J Comput Assist Tomogr 1994;18:432-438
17. Singer AA, Obuchowski NA, Einstein DM, Paushter DM. Metastasis or adenoma? Computed tomographic evaluation of the adrenal mass. Cleve Clin J Med 1994;61:200-205
18. Korobkin M, Giordano TJ, Brodeur FJ, Francis IR, Siegelman ES, Quint LE, et al. Adrenal adenomas: relationship between histologic lipid and CT and MR findings. Radiology 1996;200:743-747
19. Miyake H, Takaki H, Matsumoto S, Yoshida S, Maeda T, Mori H. Adrenal nonhyperfunctioning adenoma and nonadenoma: CT attenuation value as discriminative index. Abdom Imaging 1995;20:559-562
20. McNicholas MM, Lee MJ, Mayo-Smith WW, Hahn PF, Boland GW, Mueller PR. An imaging algorithm for the differential diagnosis of adrenal adenomas and metastases. AJR Am J Roentgenol 1995;165:1453-1459
21. Boland GW, Lee MJ, Gazelle GS, Halpern EF, McNicholas MM, Mueller PR. Characterization of adrenal masses using unenhanced CT: an analysis of the CT literature. AJR Am J Roentgenol 1998;171:201-204
22. Korobkin M, Brodeur FJ, Francis IR, Quint LE, Dunnick NR, Londy F. CT time-attenuation washout curves of adrenal adenomas and nonadenomas. AJR Am J Roentgenol 1998;170:747-752
23. Bertherat J, Mosnier-Pudar H, Bertagna X. Adrenal incidentalomas. Curr Opin Oncol 2002;14:58-63
24. Grumbach MM, Biller BM, Braunstein GD, Campbell KK, Carney JA, Godley PA, et al. Management of the clinically inapparent adrenal mass ("incidentaloma"). Ann Intern Med 2003;138:424-429
25. Nwariaku FE, Champine J, Kim LT, Burkey S, O'Keefe G, Snyder WH. Radiologic characterization of adrenal masses: the role of computed tomography-derived attenuation values. Surgery 2001;130:1068-1071
26. Leroy-Willig A, Roucayrol JC, Luton JP, Courtieu J, Niesenbaum N, Louvel A. In vitro adrenal cortex lesions characterization by NMR spectroscopy. Magn Reson Imaging 1987;5:339-344
27. Leroy-Willig A, Bittoun J, Luton JP, Louvel A, Lefevre JE, Bonnin A, et al. In vivo MR spectroscopic imaging of the adrenal glands: distinction between adenomas and carcinomas larger than 15 mm based on lipid content. AJR Am J Roentgenol 1989;153:771-773
28. Paívänsalo M, Lähde S, Merikanto J, Kallionen M. Computed tomography in primary and secondary adrenal tumours. Acta Radiol 1988;29:519-522
29. Szolar DH, Kammerhuber FH. Adrenal adenomas and nonadenomas: assessment of washout at delayed contrast-enhanced CT. Radiology 1998;207:369-375
30. Caoili EM, Korobkin M, Francis IR, Cohan RH, Platt JF, Dunnick NR, et al. Adrenal masses: characterization with combined unenhanced and delayed enhanced CT. Radiology 2002;222:629-633
31. Mayo-Smith WW, Boland GW, Noto RB, Lee MJ. State-of-theart adrenal imaging. Radiographics 2001;21:995-1012.
32. Hussain S, Belldegrun A, Seltzer SE, Richie JP, Gittes RF, Abrams HL. Differentiation of malignant from benign adrenal masses: predictive indices on computed tomography. AJR Am J Roentgenol 1985;144:61-65
33. Copeland PM. The incidentally discovered adrenal mass. Ann Intern Med 1983;98:940-945
34. Korobkin M, Francis IR, Kloos RT, Dunnick NR. The incidental adrenal mass. Radiol Clin North Am 1996;34:1037-1054
35. Mitnick JS, Bosniak MA, Megibow AJ, Naidich DP. Non-functioning adrenal adenomas discovered incidentally on computed tomography. Radiology 1983;148:495-499
36. Hamrahian AH, Ioachimescu AG, Remer EM, Motta-Ramirez G, Bogabathina H, Levin HS, et al. Clinical utility of noncontrast computed tomography attenuation value (hounsfield units) to differentiate adrenal adenomas/hyperplasias from nonadenomas: Cleveland Clinic experience. J Clin Endocrinol Metab 2005;90:871-877