Comparison of the effect of tromethamine and polyvinylpyrrolidone on dissolution properties and analgesic effect of nimesulide

AAPS PharmSciTech

Volumn 8, Issue 3, 2007, Pages

  Abdelkader, Hamdy ^a   Abdallah, Ossama Y ^b   Salem, Hesham S ^a  

^a Minia University   (Egypt)

^b Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Analgesic effect; Coprecipitation; Nimesulide; Polyvinylpyrrolidone; Tromethamine

Indexed keywords

ACETIC ACID; DRUG CARRIER; NIMESULIDE; POVIDONE; TROMETAMOL; ANALGESIC AGENT; EXCIPIENT; NONSTEROID ANTIINFLAMMATORY AGENT; SULFONAMIDE;

ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG DOSAGE FORM; DRUG DOSAGE FORM COMPARISON; DRUG SOLUBILITY; DRUG STRUCTURE; IN VIVO STUDY; INFRARED SPECTROSCOPY; MOUSE; NONHUMAN; PAIN; POLYMERIZATION; PRECIPITATION; SOLID STATE; STATISTICAL ANALYSIS; WRITHING TEST; X RAY DIFFRACTION; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; SOLUBILITY;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; MICE; POVIDONE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SULFONAMIDES; TROMETHAMINE;

EID: 34548212019     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt0803065     Document Type: Article

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