Gilbert syndrome presenting in a young boy, confirmed by the rifampin test

Israel Medical Association Journal

Volumn 9, Issue 8, 2007, Pages 626-627

  Keren, Gershon ^a,b   Mazilis, Alex ^a,b  

^a HILLEL YAFFE MEDICAL CENTER   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Autosomal recessive disorder; Gilbert syndrome; Hyperbilirubinemia; Rifampin test; Uridine diphosphate glucuronyltransferase

Indexed keywords

BILIRUBIN; BILIRUBIN GLUCURONIDE; RIFAMPICIN;

ABDOMINAL PAIN; ARTICLE; BILIRUBIN BLOOD LEVEL; CASE REPORT; FLUID RESUSCITATION; GILBERT DISEASE; HUMAN; LIVER FUNCTION TEST; MALE; NORMAL VALUE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; VOMITING;

BILIRUBIN; CHILD; DIAGNOSIS, DIFFERENTIAL; ENZYME INHIBITORS; GILBERT DISEASE; HUMANS; MALE; RIFAMPIN;

EID: 34548208588     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Gilbert A, Lereboullet P. La cholemie simple familiale. Semaine Med 1901;21: 241-3.
2. Arias IM. Chronic unconjugated hyperbilirubinemia without overt signs of hemolysis in adolescents and adults. J Clin Invest 1962; 41:2233-45.
3. Bosma PJ, Chowdhury JR, Bakker C, et al. The genetic basis of the reduced expression of bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995;333:1171-5.
4. Murthy GD, Byron D, Shoemaker D, Visweswaraiah H, Pasquale D. The utility of rifampin in diagnosing Gilbert's syndrome. Am J Gastroenterol 2001:96:1150-4.
5. Gorski JC, Vannaprasaht S, Hamman MA, et al. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity. Clin Pharmacol Ther 2003;74:275-87.