New pregnane glycosides from the roots of Cynanchum otophyllum

Steroids

Volumn 72, Issue 11-12, 2007, Pages 778-786

  Ma, Xiao Xia ^a,b   Jiang, Fang Ting ^c   Yang, Qing Xiong ^a   Liu, Xiu Hua ^c   Zhang, Ying Jun ^a   Yang, Chong Ren ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c HENAN UNIVERSITY   (China)

Author keywords

Asclepiadaceae; Cynanchum otophyllum; Otophyllosides H M; Pregnane glycosides

Indexed keywords

CAUDATIN 3 O BETA D GLUCOPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D OLEANDROPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D CYMAROPYRANOSIDE; CAUDATIN 3 O BETA D GLUCOPYRANOSYL (1-4) BETA D GLUCOPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D OLEANDROPYRANOSYL (1-4) BETA D CYMAROPYRANOSIDE; CYNANCHUM OTOPHYLLUM EXTRACT; GLYCOSIDE; PLANT EXTRACT; PREGNANE DERIVATIVE; QINGYANGSHENGENIN 3 O BETA D GLUCOPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D OLEANDROPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D DIGITOXOPYRANOSIDE; QINGYANGSHENGENIN 3 O BETA D GLUCOPYRANOSYL (1-4) BETA D GLUCOPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D OLEANDROPYRANOSYL (1-4) BETA D DIGITOXOPYRANOSIDE; QINGYANGSHENGENIN 3 O BETA D GLUCOPYRANOSYL (1-4) BETA D OLEANDROPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D DIGITOXOPYRANOSIDE; QINGYANGSHENGENIN 3 O BETA D GLUCOPYRANOSYL (1-4) BETA D THEVETOPYRANOSYL (1-4) BETA D CYMAROPYRANOSYL (1-4) BETA D DIGITOXOPYRANOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CYNANCHUM; CYNANCHUM OTOPHYLLUM; MEDICINAL PLANT; NONHUMAN; SPECTROSCOPY;

CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CARBON ISOTOPES; CYNANCHUM; GLYCOSIDES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; PLANT ROOTS; STEROIDS, HETEROCYCLIC;

APOCYNACEAE; CYNANCHUM;

EID: 34548204384     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.06.001     Document Type: Article

References (22)

1. Mu Q.Z., and Zhou Q.L. The constituents of qingyangshen (Cynanchum otophyllum scheind.). Acta Pharm Sinica 18 5 (1983) 356-362
2. Mu Q.Z., Lu J.R., and Zhou Q.L. Two new antiepilepsy compounds-otophyllosides A and B. Sci Sin Ser B (Engl Ed) 29 3 (1986) 295-301
3. Kuang P.G., Wu Y.X., Meng F.J., Kuang P.Z., Shao D.S., and Mu Q.Z. Treatment of grand mal seizures with "qingyangshen" (root of Cynanchum otophyllum) and observations on experimental animals. J Tradit Chin Med 1 1 (1981) 19-24
4. Hu Y.M., Zhang M.Q., Kuang P.G., Lang S.Y., Zhong Y.L., Wang C.L., et al. Studies of qingyangshen (root of Cynanchum otophyllum). I. Effect of qingyangshen on copper and zinc metabolism. J Tradit Chin Med 5 2 (1985) 95-98
5. Kuang P.G., Lang S.Y., Zhang F.Y., and Yang Z.L. Studies on qingyangshen (root of Cynanchum otophyllum). II. Effect of qingyangshen on metabolism of central monoamines. J Tradit Chin Med 5 3 (1985) 191-194
6. Kuang P.G., Lang S.Y., Dai F.L., Zhang D.M., Zhang F.Y., Pu C.Q., et al. Studies of qingyangshen (root of Cynanchum otophyllum). III. Effect of qingyangshen on acetylcholine concentration in mouse brain. J Tradit Chin Med 5 4 (1985) 267-270
7. Mu QZ, Shen YM, Zhou QL, inventors.. An anti-epilepsy drug, CN 1060676C. Kunming Institute of Botany, Chinese Academy of Sciences; January 17, 2001.
8. Mu QZ, Shen YM, Zhou QL, Hao XJ, inventors;. The pharmaceutical application of otophyllosides A and B, CN 1064235C. Kunming Institute of Botany, Chinese Academy of Sciences; April 11, 2001.
9. Mu QZ, Shen YM, Zhou QL, Hao XJ, inventors.. The preparation and application of otophyllosides C-G, CN 1064048C. Kunming Institute of Botany, Chinese Academy of Sciences; April 4, 2001.
10. Zhang Z.X., and Zhou J. The chemical components of Cynanchum wallichii. Acta Bot Yunnan 4 4 (1982) 413-418
11. Yamagishi T., and Mitsuhashi H. The structure of caudatin. Chem Pharm Bull 20 3 (1972) 625-626
12. Zhang Z.X., and Zhou J. The structure of wallicoside. Acta Chim Sin 41 11 (1983) 1059-1064
13. 21-steroidal glycosides isolated from Cynanchum stauntoi. Phytochemistry 52 7 (1999) 1351-1355
14. Hamed A.I., Sheded M.G., Shaheen A.E.S.M., Hamada F.A., Pizza C., and Piacente S. Polyhydroxypregnane glycosides from Oxystelma esculentum var. alpini. Phytochemistry 65 7 (2004) 975-980
15. Li X.Y., Sun H.X., Ye Y.P., Chen F.Y., and Pan Y.J. C-21 steroidal glycosides from the roots of Cynanchum chekiangense and their immunosuppressive activities. Steroids 71 1 (2006) 61-66
16. Yoshikawa K., Matsuchika K., Takahashi K., Tanaka M., Arihara S., Chang H.C., et al. Pregnane glycosides, gymnepregosides G-Q from the roots of Gymnema alternifolium. Chem Pharm Bull 47 6 (1999) 798-804
17. Yoshikawa K., Okada N., Kann Y., and Arihara S. Steroidal glycosides from the fresh stem of Stephanotis lutchuensis var. japonica (Asclepiadaceae). Chemical structures of stephanosides A-J. Chem Pharm Bull 44 10 (1996) 1790-1796
18. Warashina T., and Noro T. Steroidal glycosides from the root of Cynanchum caudatum M. Chem Pharm Bull 43 6 (1995) 977-982
19. Warashina T., and Noro T. Steroidal glycosides from roots of Cynanchum caudatum M, II. Chem Pharm Bull 43 10 (1995) 1734-1737
20. Warashina T., and Noro T. Steroidal glycosides from roots of Cynanchum caudatum M, III. Chem Pharm Bull 44 2 (1996) 358-363
21. Warashina T., and Noro T. Steroidal glycosides from roots of Cynanchum caudatum. Phytochemistry 44 5 (1997) 917-923
22. 21 steroid glycoside as antidepressants, CN 1634097A. Yunnan YunYao Laboratory Co. Ltd. July 6, 2005.