An in vivo confocal Raman study of the delivery of trans-retinol to the skin

Applied Spectroscopy

Volumn 61, Issue 8, 2007, Pages 804-811

  Pudney, Paul D A ^a   Mélot, Mickaël ^a   Caspers, Peter J ^b   Van Der Pol, Andre ^b   Puppels, Gerwin J ^b  

^a UNILEVER RESEARCH   (United Kingdom)

^b River Diagnostics BV   (Netherlands)

Author keywords

In vivo; Raman microspectroscopy; Retinol; Stratum corneum; Transdermal delivery

Indexed keywords

CARBOXYLIC ACIDS; CONFOCAL MICROSCOPY; ETHANOL; PROPYLENE; RAMAN SPECTROSCOPY; SKIN;

BIOLOGICAL PROCESSES; PROPYLENE GLYCOL; STRATUM CORNEUM; TRANS-RETINOL; TRANSDERMAL DELIVERY;

DRUG DELIVERY;

DRUG CARRIER; RETINOL; VITAMIN;

ADULT; CONFERENCE PAPER; DRUG INTERACTION; FOREARM; HUMAN; INSTRUMENTATION; INTRADERMAL DRUG ADMINISTRATION; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; RAMAN SPECTROMETRY; SKIN; SKIN ABSORPTION;

ADMINISTRATION, CUTANEOUS; ADULT; DRUG CARRIERS; DRUG INTERACTIONS; FOREARM; HUMANS; MALE; MIDDLE AGED; SKIN; SKIN ABSORPTION; SPECTRUM ANALYSIS, RAMAN; VITAMIN A; VITAMINS;

EID: 34548157005     PISSN: 00037028     EISSN: None     Source Type: Journal    
DOI: 10.1366/000370207781540042     Document Type: Conference Paper

References (29)

1. J. Lademann, H. Weigmann, C. Rickmeyer, H. Barthelmes, H. Schaefer, G. Mueller, and W. Sterry, Skin Pharmacol. Appl. Skin Physiol. 12, 247 (1999).
2. H. Weigmann, J. Lademann, H. Meffert, H. Schaefer, and W. Sterry, Skin Pharmacol. Appl. Skin Physiol. 12, 34 (1999).
3. A. Watkinson, R. S. Lee, A. E. Moore, P. D. A. Pudney, S. E. Paterson, and A. V. Rawlings, Int. J. Cosm. Sci. 24, 151 (2002).
4. J. C. Tsai, Y. L. Lo, C. Y. Lin, H. M. Sheu, and J. C. Lin, Spectroscopy 18, 423 (2004).
5. G. S. Pilgram, A. M. Van Pelt, F. Spies, J. A. Bouwstra, and H. K. Koerten, J. Microsc. 189, 71 (1998).
6. H. M. Sheu, J. Y. Y. Lee, K. W. Kuo, and J. C. Tsai, J. Dermatol. 25, 281 (1998).
7. P. W. Wertz and D. T. Downing, J. Invest. Dermatol. 94, 159 (1990).
8. P. J. Caspers, G. W. Lucassen, E. A. Carter, H. A. Bruining, and G. J. Puppels, J. Invest. Dermatol. 116, 434 (2001).
9. P. J. Caspers, G. W. Lucassen, R. Wolthuis, H. A. Bruining, and G. J. Puppels, Biospectroscopy 4, S31 (1998).
10. P. J. Caspers, G. W. Lucassen, H. A. Bruining, and G. J. Puppels, J. Raman Spectrosc. 31, 813 (2000).
11. P. J. Caspers, A. C. Williams, E. A. Carter, H. G. M. Edwards, H. A. Bruining, and G. J. Puppels, Pharmaceut. Res. 19, 1577 (2002).
12. P. M. Elias, J. Invest. Dermatol. 80, 44s (1983).
13. A. S. Michaels, S. K. Chandrasekaran, and J. E. Shaw, J. Am. Inst. Chem. Eng. 21, 985 (1975).
14. L. Landmann, Anat. Embryol. 178, 1 (1988).
15. I. H. Blank and R. J. Scheuplein, Br. J. Dermatol. 81, 4 (1969).
16. R. J. Scheuplein, J. Invest. Dermatol. 76, 31 (1976).
17. C. R. Behl, M. Barett, G. L. Flynn, T. Kurihara, K. Walters, O. Gatmaitan, N. Harper, W. Higuchi, N. F. Ho, and C. Pierson, J. Pharm. Sci. 71, 229 (1982).
18. G. J. Fisher and J. J. Voorhees, FASEB J. 10, 1002 (1996).
19. T. Shigematsu and T. Shingo, J. Dermatol. Sci. 9, 142 (1995).
20. J. Varani, J. R. L. Warner, M. Gharaee-Kermani, S. H. Phan, S. Kang, J. Chung, Z. Wang, S. C. Datta, G. J. Fisher, and J. J. Voorhees, J. Invest. Dermatol. 114, 480 (2000).
21. B. W. Barry, J. Controlled Release 15, 237 (1991).
22. G. J. Puppels and H. J. C. M. Sterenborg, (2005) "Laser safety aspects of the use of the Model 3510 Skin Composition Analyzer (SCA) in in vivo studies of human subjects", available on request from River Diagnostics.
23. B. W. Barry, H. G. M. Edwards, and A. C. Williams, J. Raman Spectrosc. 23, 641 (1992).
24. P. J. Caspers, A. van der Pol, and J. de Sterke, "Quantitative in vivo monitoring of topical caffeine by Raman spectroscopy", submitted to the 25th Conference of the International Federation of Societies of Cosmetic Chemists (Amsterdam, The Netherlands, 2007).
25. R. R. Warner, M. C. Myers, and D. A. Taylor, J. Invest. Dermatol. 90, 218 (1988).
26. T. Von Zglinicki, M. Lindberg, G. M. Roomans, and B. Forslind, Acta Derm. Venereol. 73, 340 (1993).
27. G. P. Lian, L. Chen, and L. Han, "An Evaluation of Mathematical Models for Predicting Skin Permeability", J. Pharmaceut. Sci., paper in press (2007).
28. A. C. Williams and B. W. Barry, Adv. Drug Delivery Rev. 56, 603 (2004).
29. P. D. A. Pudney, M. E. Melot, P. J. Caspers, A. Van Der Pol, and G. J. Puppels, "In-Vivo study of the effect of penetration enhancers on the delivery of retinol to skin by confocal Raman spectroscopy", Biophys. J., paper submitted (2007).