Programmed affinity extraction of molecules on a microfluidic platform

Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

Volumn , Issue , 2007, Pages 997-1002

  Nguyen, ThaiHuu ^a   Renjun, Pei ^b   Stojanovic, Milan ^b   Qiao, Lin ^a  

^a Department of Earth and Environmental Sciences   (United States)

^b Columbia University ^*  (United States)

Author keywords

Affinity sensor; Aptamer; Controlled release; Microchip; Purification; Solid phase extraction (SPE)

Indexed keywords

EXTRACTION; FLUORESCENCE MICROSCOPY; MEMS; MICROFLUIDICS; REACTION KINETICS; RNA;

AUXILIARY CHANNELS; BIOTIN; MONOPHOSPHATE COUPLING; PROGRAMMED AFFINITY EXTRACTION;

MOLECULAR STRUCTURE;

EID: 34548143312     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NEMS.2007.352186     Document Type: Conference Paper

References (16)

1. I. Karube and Y. Nomura. "Enzyme sensors for environmental analysis," J. Mol. Catal. B: Enzym., vol. 10, pp. 177-181, Sep. 2004.
2. R. Oleschuk, L. Shultz-Lockyear, Y. Ning, and D. Harrison. "Trapping of bead-based reagents within microfluidic systems: on-chip solid-phase extraction and electrochromatography," Anal. Chem., vol. 72. pp. 585-590. Feb. 2000.
3. J. Ramsey and D. Collins. "Integrated microfluidic device for solid-sphase extraction coupled to micellar electrokinetic chromatography separation," Anal. Chem., vol. 77, pp. 6664-6670, Oct. 2005.
4. C.Yu, M. Davey, F. Svec, and J. Frechet. "Monolithic porous polymer for on-chip solid-phase extraction and preconcentration prepared by photoinitiated in situ polymerization within a microfluidic device," Anal. Chem., vol. 73, pp. 5088-5096, Nov. 2001.
5. V. Meyer, Practical High-Performance Liquid Chromatography. Chichester, West Sussex, England: John Wiley & Sons, 1994. pp. 211-216.
6. S. Tombelli, M. Minunni, and M. Mascini. "Analytical applications of aptarners," Biosens. Bioelectron., vol. 20, pp. 2424-2434. June 2005.
7. J. Collett, E. Cho, and A. Ellington. "Production and processing of aptamer microarrays," Methods, vol. 37. pp. 4 - 15, Sep. 2005.
8. C Tuerk and L. Gold. "Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase," Science, vol. 249. pp. 505-510. Aug. 1990.
9. P. Langer, A. Waldrop, and D. Ward. "Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes," in Proc. Natl. Acad. Sci., vol. 78, pp. 6633-6637 Nov. 1981.
10. S. Jayasena. "Aptamers: an emerging class of molecules that rival antibodies in diagnostics," Clin. Chem., vol. 45, pp. 1628-1650, Sep. 1999.
11. S. Cho et al. "Microbead-based affinity chromatography chip using RNA aptamer modified with photocleavable linker," Electrophoresis, vol. 25, pp. 3730-3739, Nov. 2004.
12. Y. Tang, J. Yeom. J. Han, B. Bae. R. Masel, and M. Shannon. "A micro-post preconcentrator for a microscale gas chromatography system," presented at the 2005 Conf. on Miniaturized Systems for Chemistry and Life Sciences (μ-TAS), Boston, MA.
13. P.C. Wang, J. Gao, and C. Lee. "High-resolution chiral separation using microfluidics-based membrane chromatography," J. Chromatogr. A, vol. 942, pp. 115-122, Jan. 2002.
14. D. Schluter, and J. Rabe. "Dendronized polymers: synthesis, characterization, assembly at interfaces, and manipulation," Angew. Chem. Int. Ed., vol. 39, pp. 864-883, 2000.
15. M. Sassanfar and J. Szostak. "An RNA motif that binds ATP," Nature, vol. 364, pp. 550-553, Aug. 1993.
16. A. Holmberg et al. "The biotin-streptavidin interaction can be reversibly broken using water at elevated temperatures," Electrophoresis, vol. 26, pp. 501-510, Feb. 2005.