Pharmacokinetics of HZ08 in rats by liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 856, Issue 1-2, 2007, Pages 29-34

  Weng, Jing yan ^a   Song, Min ^a   Hang, Tai jun ^a   Huang, Wen long ^a   Du, Yun ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

HZ08; LC tandem MS; Pharmacokinetics; Rat plasma

Indexed keywords

RAT PLASMA; TANDEM MASS DETECTION;

ELECTROSPRAY IONIZATION; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS;

POLYAMIDES;

ANTINEOPLASTIC AGENT; ARGON; DROTAVERINE; HZ 08; LIPOSOME; N CYANO 1 [(3,4 DIMETHOXYPHENYL)METHYL] 3,4 DIHYDRO 6,7 DIMETHOXY N' OCTYL 2(1H)ISOQUINOLINE CARBOXIMIDAMIDE; TERT BUTYL METHYL ETHER; UNCLASSIFIED DRUG;

ACCURACY; ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CANCER RESISTANCE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG HALF LIFE; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FEMALE; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PLASMA CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION PROCESS;

ANIMALS; AREA UNDER CURVE; FEMALE; HYDROGEN-ION CONCENTRATION; ISOQUINOLINES; MALE; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 34548137306     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.05.013     Document Type: Article

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