Sensitivity and specificity of a commercial C6 peptide enzyme immuno assay in diagnosis of acute Lyme neuroborreliosis

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 26, Issue 9, 2007, Pages 675-677

  Skarpaas, T ^a   Ljostad U ^a   Sobye M ^a   Mygland, A ^a,b,c  

^a SØRLANDET HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

C6 PEPTIDE; DIAGNOSTIC AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC TEST; DISEASE CLASSIFICATION; ENDEMIC DISEASE; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; LYME DISEASE; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; PRIORITY JOURNAL; SCREENING; SENSITIVITY AND SPECIFICITY;

ANTIBODIES, BACTERIAL; HUMANS; IMMUNOENZYME TECHNIQUES; LYME NEUROBORRELIOSIS; SENSITIVITY AND SPECIFICITY;

EID: 34548136606     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-007-0336-y     Document Type: Article

References (10)

1. Stanek G, O'Connell S, Cimmino M, Aberer E, Kristoferitsch W, Granstrom M, Guy E, Gray J (1996) European Union Concerted Action on Risk Assessment in Lyme Borreliosis: clinical case definitions for Lyme borreliosis. Wien Klein Wochenschr 13:741-747
2. Wilske B (2003) Diagnosis of Lyme Borreliosis in Europe. Vector Borne Zoonotic Dis 3:215-27
3. Hansen K, Lebech AM (1991) Lyme neuroborreliosis: a new sensitive diagnostic assay for intrathecal synthesis of Borrelia burgdorferi-specific immunoglobulin G, A, and M. Ann Neurol 30:197-205
4. Ljostad U, Mygland A, Skarpaas T (2003) [Neuroborreliosis in Vest-Agder]. Tidsskr Nor Laegeforen 6:610-613
5. Liang FT, Steere AC, Marques AR, Johnson BJ, Miller JN, Philipp MT (1999) Sensitive and specific serodiagnosis of Lyme disease by enzyme-linked immunosorbent assay with a peptide based on an immunodominant conserved region of Borrelia burgdorferi VlsE. J Clin Microbiol 37:3990-3996
6. Panelius J, Lahdenne P, Saxen H, Carlsson SA, Heikkila T, Peltomaa M, Lauhio A, Seppala I (2003) Diagnosis of Lyme neuroborreliosis with antibodies to recombinant proteins DbpA, BBK32, and OspC, and VlsE IR6 peptide. J Neurol 250:1318-1327
7. Aguero-Rosenfeld ME, Wang G, Schwartz I, Wormser GP (2005) Diagnosis of Lyme borreliosis. Clin Microbiol Rev 18:484-509
8. Bacon RM, Biggerstaff BJ, Schriefer ME, Gilmore RD, Jr, Philipp MT, Steere AC, Wormser GP, Marques AR, Johnson BJ (2003) Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosorbent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell lysates. J Infect Dis 15:1187-1199
9. Magnarelli LA, Lawrenz M, Norris SJ, Fikrig E (2002) Comparative reactivity of human sera to recombinant VlsE and other Borrelia burgdorferi antigens in class-specific enzyme-linked immunosorbent assays for Lyme borreliosis. J Med Microbiol 51:649-655
10. Marques AR, Martin DS, Philipp MT (2002) Evaluation of the C6 peptide enzyme-linked immunosorbent assay for individuals vaccinated with the recombinanat OspA Vaccine. J Clin Microbiol 40:2591-2593