Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms

Journal of Medicinal Chemistry

Volumn 50, Issue 17, 2007, Pages 4195-4204

  Villain Guillot, Philippe ^a   Gualtieri, Maxime ^a   Bastide, Lionel ^b   Roquet, Françoise ^a   Martinez, Jean ^c   Amblard, Muriel ^c   Pugniere, Martine ^a   Leonetti, Jean Paul ^a  

^a University of Montpellier I and II   (France)

^b Selectbiotics   (France)

^c UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 [5 (3 ALLYL 4 OXO 2 THIOXOTHIAZOLIDINYLIDENEMETHYL)FURAN 2 YL]PHENYL]PROPIONIC ACID; 4 [5 (3 ALLYL 4 OXO 2 THIOXOTHIAZOLIDINYLIDENEMETHYL)FURAN 2 YL]BENZENESULFONIC ACID; BENZENE DERIVATIVE; FURAN DERIVATIVE; RHODANINE; RNA POLYMERASE; SERUM ALBUMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BIOFILM; CLOSTRIDIUM DIFFICILE; CONCENTRATION RESPONSE; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; HOSPITAL INFECTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROKARYOTE; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CHO CELLS; CRICETINAE; CRICETULUS; DNA-DIRECTED RNA POLYMERASES; FURANS; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; RHODANINE; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34548131106     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0703183     Document Type: Article

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