Systematic decoupled identification of pseudo-stoichiometry, degradation rates and kinetics

Computers and Chemical Engineering

Volumn 31, Issue 11, 2007, Pages 1449-1455

  Grosfils, A ^a   Wouwer, A Vande ^b   Bogaerts, Ph ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF MONS   (Belgium)

Author keywords

Biotechnology; Degradation rates; Identifiability; Mathematical models; Maximum likelihood estimators

Indexed keywords

BACTERIA; BIOTECHNOLOGY; CONCENTRATION (PROCESS); DEGRADATION; ENZYMES; MATHEMATICAL MODELS; PARAMETER ESTIMATION; REACTION KINETICS; SENSORS; SIMULATORS;

CONCENTRATION MEASUREMENTS; IDENTIFIABILITY; MASS BALANCES; MAXIMUM LIKELIHOOD ESTIMATORS;

STOICHIOMETRY;

BACTERIA; BIOTECHNOLOGY; CONCENTRATION (PROCESS); DEGRADATION; ENZYMES; MATHEMATICAL MODELS; PARAMETER ESTIMATION; REACTION KINETICS; SENSORS; SIMULATORS; STOICHIOMETRY;

EID: 34548130718     PISSN: 00981354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compchemeng.2006.12.007     Document Type: Article

References (14)

1. Bai F.W., Chen L.J., Zhang Z., Anderson W.A., and Moo-Young M. Continuous ethanol production and evaluation of yeast cell lysis and viability loss under very high gravity medium conditions. Journal of Biotechnology 110 (2004) 287-293
2. Bastin G., and Dochain D. On-line estimation and adaptative control of bioreactor (1990), Elsevier, Amsterdam
3. Birol G., Dorucker P., Kirdar B., Önsan Z.I., and Ülgen K. Mathematical description of ethanol fermentation by immobilised Saccharomyces cerevisiae. Process Biochemistry 33 7 (1998) 763-771
4. Bogaerts Ph., Delcoux J.-L., and Hanus R. Maximum likelihood estimation of pseudo-stoichiometry in macroscopic biological reaction schemes. Chemical Engineering Science 58 (2003) 1545-1563
5. Bogaerts, Ph., & Hanus, R. (2000). Macroscopic modelling of bioprocesses with a view to engineering applications. In Focus on Biotechnology (Ph. Thonart and M. Hofman, Ed.), Vol. IV (Engineering and Manufacturing for biotechnology).
6. Chen L., and Bastin G. Structural identifiability of the yield coefficients in bioprocess models when the reaction rates are unknown. Mathematical Biosciences 132 (1996) 35-67
7. De Assis A.J., and Filho R.M. Soft sensors development for on-line bioreactor state estimation. Computers and Chemical Engineering 24 (2000) 1099-1103
8. Glassey J., Ignova M., Ward A.C., Montague G.A., and Morris A.J. Bioprocess supervision: neural networks and knowledge based systems. Journal of Biotechnology 52 (1997) 201-205
9. Haag J.E., Vande Wouwer A., and Bogaerts Ph. Dynamic modelling of complex biological systems: A link between metabolic and macroscopic description. Mathematical Biosciences 193 (2005) 283-291
10. Hulhoven X., Vande Wouwer A., and Bogaerts Ph. On a systematic procedure for the predetermination of macroscopic reaction schemes. Bioprocess and Biosystems Engineering 27 (2005) 283-291
11. Provost A., and Bastin G. Dynamic metabolic modelling under the balanced growth condition. Journal of Process Control 14 (2004) 717-728
12. Schubert J., Simutis R., Dors M., Havlik I., and Lübbert A. Bioprocess optimization and control: Application of hybrid modelling. Journal of Biotechnology 35 (1994) 51-68
13. Sonnleitner B., and Käppeli O. Growth of Saccharomyces cerevisiae is controlled by its respiratory capacity: Formulation and verification of a hypothesis. Biotechnology and Bioengineering 28 (1986) 927-937
14. Van Impe J.F., and Bastin G. Optimal adaptive control of fed-batch fermentation processes. Controlled Engineering Practice 3 7 (1995) 939-954