Novel multi-parameter flow cytometry sensitively detects phenotypically distinct plasma cell subsets in plasma cell proliferative disorders [1]

Leukemia

Volumn 21, Issue 9, 2007, Pages 2043-2046

  Morice, W G ^a   Hanson, C A ^a   Kumar, S ^a   Frederick, L A ^a   Lesnick, C E ^a   Greipp, P R ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD38 ANTIGEN; CD45 ANTIGEN; IMMUNOGLOBULIN LIGHT CHAIN; SYNDECAN 1;

ANTIGEN EXPRESSION; BONE MARROW BIOPSY; CELL COUNT; CELL POPULATION; CELL PROLIFERATION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INTERMETHOD COMPARISON; LETTER; MAJOR CLINICAL STUDY; PHENOTYPIC VARIATION; PLASMA CELL; PLASMA CELL DYSCRASIA; PRIORITY JOURNAL; PROGNOSIS; SENSITIVITY ANALYSIS;

EID: 34548125333     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404712     Document Type: Letter

References (8)

1. San Miguel JF, Almeida J, Mateo G, Bladé J, Lopez-Berges C, Caballero D et al. Immunophenotypic evaluation of the plasma cell compartment in multiple myeloma: A tool for comparing the efficacy of different treatment strategies and predicting outcome. Blood 2002; 99: 1853-1856.
2. Sarasquete ME, Garcia-Sanz R, Gonzalez D, Martinez J, Mateo G, Martinez P et al. Minimal residual disease monitoring in multiple myeloma: a comparison between allelic-specific oligonucleotide real-time quantitative polymerase chain reaction and flow cytometry. Haematologica 2005; 90: 1365-1372.
3. Greipp PR, Kumar S. Plasma cell labeling index. Methods Mol Med 2005; 113: 25-35.
4. Lin P, Owens R, Tricot G, Wilson CS. Flow cytometric immunophenotypic analysis of 306 cases of multiple myeloma. Am J Clin Pathol 2004; 121: 482-488.
5. Lin P, Hao S, Handy BC, Bueso-Ramos CE, Medeiros LJ, Lymphoid neoplasms associated with IgM paraprotein: A study of 382 patients. Am J Clin Pathol 2005; 123: 200-205.
6. Bataille R, Robillard N, Pellat-Deceunynck C, Amiot M. A cellular model for myeloma cell growth and maturation based on an intraclonal CD45 hierarchy. Immunol Rev 2003; 194: 105-111.
7. Kumar S, Rajkumar SV, Kimlinger T, Greipp PR, Witzig TE. Cd45 expression by bone marrow plasma cells in multiple myeloma: Clinical and biological correlations. Leukemia 2005; 19: 1466-1470.
8. Rawstron AC, Barrans SL, Blythe D, English A, Richards SJ, Fenton JA et al. In multiple myeloma, only a single stage of neoplastic plasma cell differentiation can be identified by vla-5 and CD45 expression. Br J Haematol 2001; 113: 794-802.